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Autor:
Megan A Palmer, Khalidah Ibraheem, Myria Ioannou, Andrew Collett, Michael Peake, Christopher Dunnill, Nikolaos T. Georgopoulos, Adrian Smith
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
Chemotherapy-induced alopecia (CIA) represents the most distressing side-effect for cancer patients. Scalp cooling is currently the only treatment to combat CIA, yet little is known about its cytoprotective effects in human hair follicles (HF). We ha
Autor:
Maria Di Bari, María Elena Sales, Alejandro Javier Español, Yamila Sanchez, Ada Maria Tata, Agustina Reina Salem, Ilaria Cristofaro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0226450 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 15, Iss 9, p e0226450 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Triple negative tumors are more aggressive than other breast cancer subtypes and there is a lack of specific therapeutic targets on them. Since muscarinic receptors have been linked to tumor progression, we investigated the effect of metronomic thera
Autor:
Siu Yi Lee, G. Eric Blair, Christopher W. Wasson, Molly R. Patterson, Yigen Li, Ethan L. Morgan, Andrew Macdonald, Katherine L. Harper, Adrian Whitehouse, Emma L. Ryder, Stephen Griffin
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 6, p e1008624 (2020)
PLoS Pathogens, Vol 16, Iss 6, p e1008624 (2020)
Human papillomaviruses (HPV) are a major cause of malignancy worldwide. They are the aetiological agents of almost all cervical cancers as well as a sub-set of other anogenital and head and neck cancers. Hijacking of host cellular pathways is essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f790f0f257673bcea947648c172db203
https://eprints.whiterose.ac.uk/161071/8/journal.ppat.1008624.pdf
https://eprints.whiterose.ac.uk/161071/8/journal.ppat.1008624.pdf
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0235090 (2020)
PLoS ONE, Vol 15, Iss 6, p e0235090 (2020)
Tumor is a prevalent great threat to public health worldwide and multidrug resistance (MDR) of tumor is a leading cause of chemotherapy failure. Nanomedicine has shown prospects in overcoming the problem. Doxorubicin (DOX), a broad-spectrum anticance
Autor:
Nassim Ledoux, William-Naud Gauthier, Pauline Adjibade, Edouard W. Khandjian, Bryan Simoneau, Rachid Mazroui, Melisse Nkurunziza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0231894 (2020)
PLoS ONE, Vol 15, Iss 5, p e0231894 (2020)
Stress granules (SG) are cytoplasmic RNA granules that form during various types of stress known to inhibit general translation, including oxidative stress, hypoxia, endoplasmic reticulum stress (ER), ionizing radiations or viral infection. Induction
Autor:
Arif Kodza, Rakesh K. Singh, Kyu Kwang Kim, Aaron Jones, Rachael Turner, Richard G. Moore, Negar Khazan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0232253 (2020)
PLoS ONE, Vol 15, Iss 5, p e0232253 (2020)
Proteases have been implicated in the tumorigenesis and aggressiveness of a variety of cancer types. In fact, proteases have proven to be very clinically useful as tumor biomarkers in the blood of patients. Proteases are typically involved in complex
Autor:
Daniela Dettori, Jéssica Zani Lacerda, Daniela Taverna, Lívia Carvalho Ferreira, Francesca Orso, Debora Aparecida Pires de Campos Zuccari, Thaiz F. Borin
Publikováno v:
PLoS ONE
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 15, Iss 2, p e0228062 (2020)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 15, Iss 2, p e0228062 (2020)
Made available in DSpace on 2020-12-10T19:59:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-03 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Melatonin, a hormone secreted by pineal gland, exerts antimetastatic effect
Autor:
J.M. Galbis, Javier Alcácer, José Javier Martín de Llano, María Oliver, Carmen Carda, Manuel de la Mata, María Sancho-Tello, Julian Carretero, Lara Milian, Carlos Camps
Publikováno v:
PLoS ONE
PLoS One
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
PLoS ONE, Vol 15, Iss 2, p e0228909 (2020)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
PLoS One
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
PLoS ONE, Vol 15, Iss 2, p e0228909 (2020)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Background/Objective Patients with non-small cell lung cancer (NSCLC) develop resistance to antitumor agents by mechanisms that involve the epithelial-to-mesenchymal transition (EMT). This necessitates the development of new complementary drugs, e.g.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227081 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227081 (2020)
Chronic inflammation fundamentally influences cancer risk and development. A mechanism of chronic inflammation is the formation of inflammasome complexes which results in the sustained secretion of the pro-inflammatory cytokines IL1β and IL18. Infla
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227261 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227261 (2020)
The epidermal growth factor receptor inhibitor cetuximab is the only oncogene-targeted agent that has been FDA approved for the treatment of head and neck squamous cell carcinoma (HNSCC). Currently, there are no biomarkers used in the clinic to predi