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Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188195 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188195 (2017)
Background Several case-control studies reported the relationship between single nucleotide polymorphisms (SNPs) in HSP70 genes and noise-induced hearing loss (NIHL). However, their conclusions are conflicting. This meta-analysis aims to identify the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238938 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238938 (2020)
BackgroundDespite having the high rate of stillbirth in most of the countries of South Asia, there is a lack of synthesized evidence based on factors associated with stillbirth. This study systematically synthesizes the evidence on factors associated
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238784 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238784 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
Apela, a novel endogenous peptide ligand for the G-protein-coupled apelin receptor, was first discovered and identified in human embryonic stem cells in 2013. Apela has showed some biological functions in promoting angiogenesis and inducing vasodilat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
Pneumocystis pneumonia (PCP) is an opportunistic and potentially life-threatening infection of AIDS patients caused by the fungus Pneumocystis jirovecii (P. jirovecii). Trimethoprim-sulfamethoxazole (TMP-SMX) is the most commonly used drug combinatio
Autor:
Susanna Ricci, Stefano De Giorgi, Elisa Lazzeri, Alice Luddi, Stefania Rossi, Paola Piomboni, Vincenzo De Leo, Gianni Pozzi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207684 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207684 (2018)
Background Infertility is estimated to affect approximately 9–30% of reproductive-aged couples. Several conditions involving one or both partners may contribute to infertility. The aim of this study is to evaluate the role of asymptomatic genital t
Autor:
Akito Iwanaga, Tomoe Sano, Takashi Owaki, Hiroki Sato, Keiichi Seki, Michitaka Imai, Terasu Honma, Toshiaki Yoshida, Shuji Terai, Toru Ishikawa, Yujiro Nozawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206621 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206621 (2018)
Background and aim Awareness of eosinophilic esophagitis (EoE) has gradually increased in Japan, therefore the characteristics of this disease in the Japanese patient population need to be elucidated. This study aimed to investigate the features of E
Autor:
Hon S. Leong, Paul C. Boutros, James C. Lacefield, Matthew R. Lowerison, Alessandro Datti, Joe S. Mymryk, Kara M. Ruicci, John W. Barrett, Stephenie D. Prokopec, Kevin Fung, Karlee Searle, Frederick S. Vizeacoumar, Nicole Pinto, Anthony C. Nichols, Danielle MacNeil, John Yoo
Publikováno v:
PLoS ONE
Anatomy and Cell Biology Publications
PloS one, vol 13, iss 11
PLoS ONE, Vol 13, Iss 11, p e0207152 (2018)
Anatomy and Cell Biology Publications
PloS one, vol 13, iss 11
PLoS ONE, Vol 13, Iss 11, p e0207152 (2018)
Anaplastic thyroid cancer (ATC) is a rare and lethal human malignancy with no known effective therapies in the majority of cases. Despite the use of conventional treatments such as chemotherapy, radiation and surgical resection, this disease remains
Autor:
Manuel Larragoity, Rebecca E. DeJesus, Armando Varela-Ramirez, Lisett Contreras, Paulina J. Villanueva, Sarah T. Baca, Renato J. Aguilera, Alberto Martínez, Denisse A. Gutierrez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206467 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206467 (2018)
The potent antimalarial drug pyronaridine (PND) was tested for its potential as an anticancer drug. After exposing cancerous (17) and non-cancerous (2) cells to PND for 72 hr, PND was found to exhibit consistent and potent cytotoxic activity at low m
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0204081 (2018)
PLoS ONE, Vol 13, Iss 11, p e0204081 (2018)
Apical periodontitis is frequently associated with the presence of bacteria biofilm, which has an indisputable impact on the prognosis of endodontic therapy due to the high resistance to adverse environmental conditions, chemicals, and antibiotic the
Ribosome display for the rapid generation of high-affinity Zika-neutralizing single-chain antibodies
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0205743 (2018)
PLoS ONE, Vol 13, Iss 11, p e0205743 (2018)
Background Zika virus (ZIKV) is an emerging pathogen with no approved therapeutics and only limited diagnostics available. To address this gap, six mouse single-chain antibodies (scFvs) to ZIKV envelope (E) protein were isolated rapidly and efficient