Zobrazeno 1 - 10
of 439
pro vyhledávání: ''
Autor:
Joseph Leedale, Fiona Roberts, Craig Murdoch, Simon Walker-Samuel, Rebecca J. Shipley, Hannah West, Paul W. Sweeney, Helen E. Colley, Steven D. Webb
Publikováno v:
PLoS ONE
PLoS One
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
PLOS ONE
PLoS One
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
PLOS ONE
Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for nanop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e995e8260976047379fc9cd9e068ae26
https://www.repository.cam.ac.uk/handle/1810/325830
https://www.repository.cam.ac.uk/handle/1810/325830
Autor:
Fatima Noor, Muhammad Hamzah Saleem, Jen-Tsung Chen, Muhammad Rizwan Javed, Wafa Abdullah Al-Megrin, Sidra Aslam
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254678 (2021)
PLoS ONE, Vol 16, Iss 7, p e0254678 (2021)
Extramammary Paget’s disease (EMPD) is an intra-epidermal adenocarcinoma. Till now, the mechanisms underlying the pathogenesis of scrotal EMPD is poorly known. This present study aims to explore the knowledge of molecular mechanism of scrotal EMPD
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254783 (2021)
PLoS ONE, Vol 16, Iss 7, p e0254783 (2021)
An array of isoforms of the nuclear estrogen receptor alpha (ER-α) protein contribute to heterogeneous response in breast cancer (BCa); yet, a single-cell analysis tool that distinguishes the full-length ER-α66 protein from the activation function-
Autor:
Salvatore La Rosa, Helen Morrison, Jie Huang, Rajarshi Guha, Li Jiang, Yongzheng He, Gary L. Johnson, Steven P. Angus, Eric T. Hawley, Vijaya Ramesh, Justin Guinney, Sarah S. Burns, Jin Yuan, Roberta L. Beauchamp, Lars Björn Riecken, Cristina Fernandez-Valle, Marc Ferrer, Charles W. Yates, Serkan Erdin, Abbi Smith, Waylan K. Bessler, D. Bradley Welling, D. Wade Clapp, Shelley Dixon, Scott R. Plotkin, Ming Poi, Thomas S. K. Gilbert, Anat Stemmer-Rachamimov, Alejandra M. Petrilli, Craig J. Thomas, Xiaohong Li, Qingbo Lu, David R. Jones, James F. Gusella, Long-Sheng Chang, Andrea R. Masters, Xiaohu Zhang, Janet L. Oblinger, Jaishri O. Blakeley, Stephen J. Haggarty
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic syndrome caused by mutations in the NF2 tumor suppressor gene resulting in multiple schwannomas and meningiomas. There are no FDA approved therapies for these tumors and their relentless
Autor:
Pornchai Rojsitthisak, Koichi Matsuda, Watchara Sakares, Chizu Tanikawa, Varalee Yodsurang, Muttarin Lothong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0255179 (2021)
PLoS ONE, Vol 16, Iss 7, p e0255179 (2021)
Collagen XVII (COL17), a cell-matrix adhesion protein, has been found to be suppressed in breast cancer. Our previous data demonstrated a preventive role of COL17 in breast cancer invasiveness. The present study used the stable COL17-overexpressing M
Autor:
David J. Prezant, Rachel Lam, Sophia Kwon, James S. Kim, Anna Nolan, Mengling Liu, George Crowley
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 7, p e1009144 (2021)
PLoS Computational Biology, Vol 17, Iss 7, p e1009144 (2021)
Biomarkers predict World Trade Center-Lung Injury (WTC-LI); however, there remains unaddressed multicollinearity in our serum cytokines, chemokines, and high-throughput platform datasets used to phenotype WTC-disease. To address this concern, we used
Autor:
Madoka Sakata-Matsuzawa, Katsuya Nakai, Atsushi Kuno, Mitsue Saito, Tatsuro Irimura, Yoshiya Horimoto, Miki Noji, Kaori Denda-Nagai, Haruhiko Fujihira, Katrin Ishii-Schrade, Misato Okazaki, Atsushi Matsuda
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0250747 (2021)
PLoS ONE, Vol 16, Iss 5, p e0250747 (2021)
Introduction Molecular and cellular characteristics of the relapse-prone subset within triple-negative breast cancer (TNBC) remain unclear. Aberrant glycosylation is involved in the malignant behavior of cancer cells. In the present study, we aimed t
Autor:
Hiromi Kataoka, Taketo Suzuki, Hirotada Nishie, M. Sasaki, Keiji Ozeki, Hiroshi Ichikawa, Mamoru Tanaka, Takaya Shimura, Satoshi Tanida, Eiji Kubota
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249650 (2021)
PLoS ONE, Vol 16, Iss 4, p e0249650 (2021)
Gastrointestinal stromal tumor (GIST) diagnosis using conventional gastrointestinal endoscopy is difficult because such malignancies cannot be distinguished from other types of submucosal tumors. Photodynamic diagnosis (PDD) is based on the preferent
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249388 (2021)
PLoS ONE, Vol 16, Iss 4, p e0249388 (2021)
Oncogene addiction is a cellular property by which cancer cells become highly dependent on the expression of oncogenes for their survival. Oncogene addiction can be exploited to design molecularly targeted drugs that kill only cancer cells by inhibit
Autor:
Yanan Guo, Izabela A. Malinowska, Evelyn M Mrozek, David J. Kwiatkowski, Vineeta Bajaj, Jianming Zhang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0248380 (2021)
PLoS ONE, Vol 16, Iss 4, p e0248380 (2021)
Inactivating mutations in either TSC1 or TSC2 cause Tuberous Sclerosis Complex, an autosomal dominant disorder, characterized by multi-system tumor and hamartoma development. Mutation and loss of function of TSC1 and/or TSC2 also occur in a variety o