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Autor:
Matilda Aberese-Ako, Evelyn K. Ansah, Gifty Dufie Ampofo, Pascal Magnussen, Harry Tagbor, Margaret Gyapong
Publikováno v:
PLoS ONE
Aberese-Ako, M, Magnussen, P, Ampofo, G D, Gyapong, M, Ansah, E & Tagbor, H 2021, ' An ethnographic study of how health system, socio-cultural and individual factors influence uptake of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a Ghanaian context ', PLoS ONE, vol. 16, no. 10, e0257666 . https://doi.org/10.1371/journal.pone.0257666
PLoS ONE, Vol 16, Iss 10, p e0257666 (2021)
Aberese-Ako, M, Magnussen, P, Ampofo, G D, Gyapong, M, Ansah, E & Tagbor, H 2021, ' An ethnographic study of how health system, socio-cultural and individual factors influence uptake of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a Ghanaian context ', PLoS ONE, vol. 16, no. 10, e0257666 . https://doi.org/10.1371/journal.pone.0257666
PLoS ONE, Vol 16, Iss 10, p e0257666 (2021)
Background Intermittent preventive treatment of malaria among pregnant women with sulfadoxine-pyrimethamine (IPTp-SP), is one of the three recommended interventions for the prevention of malaria in pregnancy (MiP) in sub-Sahara Africa. The World Heal
Autor:
Glenda Lassi, Maria Pino-Yanes, Somnath Mukhopadhyay, Roger Tavendale, Antonio Espuela-Ortiz, Karen Wilson, Natalia Hernandez-Pacheco, Colin N. A. Palmer, Simon Young, Steve Turner, Adam Platt, Cyrielle Maroteau, Fiona Carr, Esteban G. Burchard, Anke-Hilse Maitland-van der Zee, Esther Herrera-Luis, James D. Chalmers, Sundararajan Srinivasan
Publikováno v:
PLoS ONE, 16(9 September):e0257396. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257396 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257396 (2021)
Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the role of theLTA4Hregulatory variant rs2660845 and age of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e583b11172691656d2a829454145a0c7
http://sro.sussex.ac.uk/id/eprint/101847/5/journal.pone.0257396.pdf
http://sro.sussex.ac.uk/id/eprint/101847/5/journal.pone.0257396.pdf
Autor:
Jean-René Kiechel, Borimas Hanboonkunupakarn, James Pike, Nicholas J. White, Sue J. Lee, Caterina I. Fanello, Xin Hui S Chan, Yan Naung Win, Bernhards Ogutu, Elizabeth A. Ashley, Marie A. Onyamboko, André Siqueira, Walter Rj Taylor, Ilsa L. Haeusler, Maryam Hanafiah, Marcus Vg Lacerda, Abdoulaye Djimde
Publikováno v:
PLoS Medicine, Vol 18, Iss 9, p e1003766 (2021)
PLoS Medicine
PLoS Medicine
Background Amodiaquine is a 4-aminoquinoline antimalarial similar to chloroquine that is used extensively for the treatment and prevention of malaria. Data on the cardiovascular effects of amodiaquine are scarce, although transient effects on cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d315daca514bda2780eaf237c6ff48d
https://doi.org/10.1371/journal.pmed.1003766
https://doi.org/10.1371/journal.pmed.1003766
Autor:
Amrit P. Singh, Frank Schmitz, Adam Z. Rosenthal, Madhav V. Dhodapkar, Antje Hoering, Daisy Alapat, Yan Ren, Maurizio Zangari, Kelsie Smith, Samuel A. Danziger, Jake Gockley, Andrew Dervan, Alexander V. Ratushny, Mark McConnell, Robert M. Hershberg, Suzana Couto, Brian A Walker, Faith E. Davies, Alison Fitch, Wilbert B. Copeland, Gareth J. Morgan, Bart Barlogie, Phil Farmer, David J. Reiss, Brian Fox, Mary H. Young, Frits van Rhee, Cody Ashby, Katie Newhall, Nathan Petty, Michael A Bauer, Robert Z. Orlowski, Matthew Trotter
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
Background The tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, w
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 9, p e1009936 (2021)
PLoS Pathogens, Vol 17, Iss 9, p e1009936 (2021)
While Entamoeba histolytica (Eh)-induced pro-inflammatory responses are critical in disease pathogenesis, the downstream signaling pathways that subsequently dampens inflammation and the immune response remains unclear. Eh in contact with macrophages
Correction: Phenylephrine induces relaxation of longitudinal strips from small arteries of goat legs
Autor:
Alen Major Venis, Sathya Subramani, Soosai Manickam Amirtham, Kawin Padmaja Marconi, Renu Raj, Bhavithra Bharathi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
Alpha adrenergic stimulation is known to produce vasoconstriction. We have earlier shown that, in spiral strips of small arteries Phenylephrine (PE) caused vasorelaxation under high nitric oxide (NO) environment. However on further experimentation it
Autor:
Pierre Chauvin, Charles Lefevre, Julien Letheulle, Stéphane Jouneau, Bertrand De Latour, Mallorie Kerjouan, Betsega Bayeh, Pierre Tattevin, David Luque Paz, Mathieu Lederlin, Florence Poizeau
Publikováno v:
PLoS ONE
PLoS ONE, 2021, 16 (9), pp.e0257339. ⟨10.1371/journal.pone.0257339⟩
PLoS ONE, Public Library of Science, 2021, 16 (9), pp.e0257339. ⟨10.1371/journal.pone.0257339⟩
PLoS ONE, Vol 16, Iss 9, p e0257339 (2021)
PLoS ONE, 2021, 16 (9), pp.e0257339. ⟨10.1371/journal.pone.0257339⟩
PLoS ONE, Public Library of Science, 2021, 16 (9), pp.e0257339. ⟨10.1371/journal.pone.0257339⟩
PLoS ONE, Vol 16, Iss 9, p e0257339 (2021)
Introduction Evacuation of infected fluid in pleural infections is essential. To date, the use of an intrapleural fibrinolytic agent such as urokinase and DNase has not yet been assessed in infections managed by repeated therapeutic thoracentesis (RT
Autor:
Connor G. G. Bamford, Milagros Rodriguez Collados, Alfredo Castello, Srikeerthana Kuchi, David Robertson, Nardus Mollentze, Sam J. Wilson, Joseph Busby, Arthur Wickenhagen, Douglas G. Stewart, Richard J. Orton, Siddharth Bakshi, Quan Gu, Elena Sugrue, Matthew L. Turnbull, Daniel G. Streicker, Massimo Palmarini, Suzannah J. Rihn, Andrew Shaw, Ana Filipe da Silva, Paul C. D. Johnson, Katherine Smollett
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 9, p e3001352 (2021)
PLoS Biology, Vol 19, Iss 9, p e3001352 (2021)
Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while sparing the host mRNAs that encode antiviral effectors. Here, we show that highly upregulated int
Autor:
Lorraine Tsitsi Pfavayi, Arnold Mutemeri, Dixon Chibanda, Francisca Mutapi, Takafira Mduluza, Derick Nii Mensah Osakunor, Rivka M. Lim, Simbarashe Rusakaniko, Maritha Kasambala
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009660 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 8 (2021)
Mutapi, F, Pfavayi, L T, Osakunor, D N M, Lim, R, Kasambala, M, Muemeri, A, Rusakaniko, S, Chibanda, D & Mduluza, T 2021, ' Assessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the griffiths scales of child development ', PLoS Neglected Tropical Diseases, vol. 15, no. 8, e0009660 . https://doi.org/10.1371/journal.pntd.0009660
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009660 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 8 (2021)
Mutapi, F, Pfavayi, L T, Osakunor, D N M, Lim, R, Kasambala, M, Muemeri, A, Rusakaniko, S, Chibanda, D & Mduluza, T 2021, ' Assessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the griffiths scales of child development ', PLoS Neglected Tropical Diseases, vol. 15, no. 8, e0009660 . https://doi.org/10.1371/journal.pntd.0009660
There is a paucity of reference early childhood development (ECD) data at community level in rural Africa. Our objective was to conduct a comprehensive assessment of ECD in rural Zimbabwe and determine the impact of stunting and schistosome infection
Autor:
Pan Xiaoké, Amandeep K. Sandhu, Jurjan Aman, Etto C. Eringa, Camiel V. J. Box, Geesje M. Dallinga-Thie, Alexander H. Turaihi
Publikováno v:
PLOS ONE, 16(7):0250442. Public Library of Science
PLoS ONE, 16(7 July):e0250442. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0250442 (2021)
Box, C V J, Sandhu, A K, Turaihi, A H, Xiaoke, P, Dallinga-Thie, G, Aman, J & Eringa, E C 2021, ' Effects of imatinib on vascular insulin sensitivity and free fatty acid transport in early weight gain ', PLoS ONE, vol. 16, no. 7 . https://doi.org/10.1371/journal.pone.0250442
PLoS ONE, 16(7). Public Library of Science
PLoS ONE, 16(7 July):e0250442. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0250442 (2021)
Box, C V J, Sandhu, A K, Turaihi, A H, Xiaoke, P, Dallinga-Thie, G, Aman, J & Eringa, E C 2021, ' Effects of imatinib on vascular insulin sensitivity and free fatty acid transport in early weight gain ', PLoS ONE, vol. 16, no. 7 . https://doi.org/10.1371/journal.pone.0250442
PLoS ONE, 16(7). Public Library of Science
Background Vascular endothelial dysfunction is an essential part of the pathophysiology of type 2 diabetes and its complications. In type 2 diabetes, endothelial dysfunction is characterized by reduced insulin signaling and increased transendothelial