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Autor:
Ulrike Held, Maria M. Wertli, Eva Blozik, Andri Signorell, Johann Steurer, Jakob M Burgstaller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
Burgstaller, Jakob M; Held, Ulrike; Signorell, Andri; Blozik, Eva; Steurer, Johann; Wertli, Maria M. (2020). Increased risk of adverse events in non-cancer patients with chronic and high-dose opioid use-A health insurance claims analysis. PLoS ONE, 15(9), e0238285. Public Library of Science 10.1371/journal.pone.0238285
PLoS ONE, Vol 15, Iss 9, p e0238285 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
Burgstaller, Jakob M; Held, Ulrike; Signorell, Andri; Blozik, Eva; Steurer, Johann; Wertli, Maria M. (2020). Increased risk of adverse events in non-cancer patients with chronic and high-dose opioid use-A health insurance claims analysis. PLoS ONE, 15(9), e0238285. Public Library of Science 10.1371/journal.pone.0238285
PLoS ONE, Vol 15, Iss 9, p e0238285 (2020)
BackgroundChronic and high dose opioid use may result in adverse events. We analyzed the risk associated with chronic and high dose opioid prescription in a Swiss population.MethodsUsing insurance claims data covering one-sixth of the Swiss populatio
Autor:
Joonghyun Ahn, Seung-Hwa Lee, Jeong Jin Min, Keumhee C. Carriere, Ji-Hye Kwon, Jong-Hwan Lee, Jungchan Park, Ah-ran Oh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238661 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238661 (2020)
We evaluated whether volatile anesthetics can improve the postoperative outcomes of non-cardiac surgery in patients with preoperative myocardial injury defined by the cardiac troponin elevation. From January 2010 to June 2018, 1254 adult patients wit
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
Pneumocystis pneumonia (PCP) is an opportunistic and potentially life-threatening infection of AIDS patients caused by the fungus Pneumocystis jirovecii (P. jirovecii). Trimethoprim-sulfamethoxazole (TMP-SMX) is the most commonly used drug combinatio
Publikováno v:
PLoS ONE
PLoS ONE, 15 (10)
PLoS ONE, Vol 15, Iss 10 (2020)
PLoS ONE, Vol 15, Iss 10, p e0239365 (2020)
PLoS ONE, 15 (10)
PLoS ONE, Vol 15, Iss 10 (2020)
PLoS ONE, Vol 15, Iss 10, p e0239365 (2020)
The growth of filamentous fungi during the spontaneous cocoa bean fermentation leads to inferior cocoa bean quality and poses a health risk for consumers due to the potential accumulation of mycotoxins. We recently developed anti-fungal cultures with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce0efcff0414f936a9b34ceecd001c2
Autor:
Hon S. Leong, Paul C. Boutros, James C. Lacefield, Matthew R. Lowerison, Alessandro Datti, Joe S. Mymryk, Kara M. Ruicci, John W. Barrett, Stephenie D. Prokopec, Kevin Fung, Karlee Searle, Frederick S. Vizeacoumar, Nicole Pinto, Anthony C. Nichols, Danielle MacNeil, John Yoo
Publikováno v:
PLoS ONE
Anatomy and Cell Biology Publications
PloS one, vol 13, iss 11
PLoS ONE, Vol 13, Iss 11, p e0207152 (2018)
Anatomy and Cell Biology Publications
PloS one, vol 13, iss 11
PLoS ONE, Vol 13, Iss 11, p e0207152 (2018)
Anaplastic thyroid cancer (ATC) is a rare and lethal human malignancy with no known effective therapies in the majority of cases. Despite the use of conventional treatments such as chemotherapy, radiation and surgical resection, this disease remains
Autor:
Brandon J. Ausk, Ted S. Gross, Edith M. Gardiner, Leah E. Worton, Steven D. Bain, Ronald Y. Kwon, Leah M. Downey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
At sufficient dose, intramuscular injection of Botulinum toxin A causes muscle wasting that is physiologically consistent with surgical denervation and other types of neuromuscular dysfunction. The aim of this study was to clarify early molecular and
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
Opioids are widely used for treating different types of pains, but overuse and abuse of prescription opioids have led to opioid epidemic in the United States. Besides analgesic effects, chronic use of opioid can also cause tolerance, dependence, and
Autor:
John G.T. Augoustides, Elizabeth Mahanna-Gabrielli, Cecilia Kim, Todd A. Miano, Joseph E. Bavaria, W. Andrew Kofke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207941 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207941 (2018)
Introduction Patients undergoing cardiac surgery are at high risk for postoperative delirium, which is associated with longer hospital and intensive care lengths of stays, increased morbidity and mortality. Because sleep disturbances are common in de
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207750 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207750 (2018)
N-(4-fluorophenyl)-N'-phenyl-N"-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine [ASP2905] is a potent and selective inhibitor of the potassium voltage-gated channel subfamily H member 3 (KCNH3) that was originally identified in our laboratory. K
Autor:
Yi Yu, Peter E. Kima, Naixin Zhang, Neil E. Reiner, Stella Chen, Devki Nandan, Brian Schwartz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206920 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206920 (2018)
Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally bioavailable and cost-effective drugs for the treatment of leishmaniasis. It has recently