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Autor:
Ulrike Held, Maria M. Wertli, Eva Blozik, Andri Signorell, Johann Steurer, Jakob M Burgstaller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
Burgstaller, Jakob M; Held, Ulrike; Signorell, Andri; Blozik, Eva; Steurer, Johann; Wertli, Maria M. (2020). Increased risk of adverse events in non-cancer patients with chronic and high-dose opioid use-A health insurance claims analysis. PLoS ONE, 15(9), e0238285. Public Library of Science 10.1371/journal.pone.0238285
PLoS ONE, Vol 15, Iss 9, p e0238285 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
Burgstaller, Jakob M; Held, Ulrike; Signorell, Andri; Blozik, Eva; Steurer, Johann; Wertli, Maria M. (2020). Increased risk of adverse events in non-cancer patients with chronic and high-dose opioid use-A health insurance claims analysis. PLoS ONE, 15(9), e0238285. Public Library of Science 10.1371/journal.pone.0238285
PLoS ONE, Vol 15, Iss 9, p e0238285 (2020)
BackgroundChronic and high dose opioid use may result in adverse events. We analyzed the risk associated with chronic and high dose opioid prescription in a Swiss population.MethodsUsing insurance claims data covering one-sixth of the Swiss populatio
Autor:
Joonghyun Ahn, Seung-Hwa Lee, Jeong Jin Min, Keumhee C. Carriere, Ji-Hye Kwon, Jong-Hwan Lee, Jungchan Park, Ah-ran Oh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238661 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238661 (2020)
We evaluated whether volatile anesthetics can improve the postoperative outcomes of non-cardiac surgery in patients with preoperative myocardial injury defined by the cardiac troponin elevation. From January 2010 to June 2018, 1254 adult patients wit
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
Opioids are widely used for treating different types of pains, but overuse and abuse of prescription opioids have led to opioid epidemic in the United States. Besides analgesic effects, chronic use of opioid can also cause tolerance, dependence, and
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207750 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207750 (2018)
N-(4-fluorophenyl)-N'-phenyl-N"-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine [ASP2905] is a potent and selective inhibitor of the potassium voltage-gated channel subfamily H member 3 (KCNH3) that was originally identified in our laboratory. K
Autor:
W. Ken Redekop, Carin A. Uyl-de Groot, Amir Ansaripour, Kazem Zendehdel, Fatemeh Sadeghi, Niki Tadayon
Publikováno v:
PLoS ONE
PLoS One (online), 13(10). Public Library of Science
PLoS ONE, Vol 13, Iss 10, p e0205079 (2018)
PLoS One (online), 13(10). Public Library of Science
PLoS ONE, Vol 13, Iss 10, p e0205079 (2018)
textabstractIntroduction Patient registries play an important role in obtaining real-world evidence of the cost-effectiveness of treatments. However, their implementation is costly and sometimes infeasible in many middle-income countries (MICs). We e
Autor:
Chung-Chou H. Chang, Timothy S. Anderson, Ruoxin Zhang, Wei-Hsuan Lo-Ciganic, Julie M. Donohue, Seth Richards-Shubik, Haiden A. Huskamp, Hasan Guclu, Walid F. Gellad, Stefanie P. Junker, Niteesh K. Choudhry
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204826 (2018)
PLoS ONE, Vol 13, Iss 10, p e0204826 (2018)
Although physicians learn about new medical technologies from their peers, the magnitude and source of peer influence is unknown. We estimate the effect of peer adoption of three first-in-class medications (dabigatran, sitigliptin, and aliskiren) on
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0203380 (2018)
PLoS ONE, Vol 13, Iss 9, p e0203380 (2018)
Background Anticoagulant therapy is recommended in patients with atrial fibrillation (AF) but remains underused. The proper use of anticoagulants has been encouraged in guidelines frequently published over the past two decades. Materials and methods
Autor:
Christine Lohmann, Andreas A. Giannopoulos, Aju P. Pazhenkottil, Dominik C. Benz, Anton S. Becker, Ahmed Haider, Irene A. Burger, Catherine Gebhard, Susan Bengs, Monika Maredziak, Oliver Gaemperli, Christoph Gräni, Valerie Treyer, Tobias A. Fuchs, Ken Kudura, Moritz Schwyzer, Michael Fiechter, Philipp A. Kaufmann, Michael Messerli, Ronny R. Buechel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0202302 (2018)
PLoS ONE, Vol 13, Iss 8, p e0202302 (2018)
BACKGROUND:Sexual dimorphism in cardiac sympathetic outflow has recently gained attention in the context of Takotsubo cardiomyopathy. Previous studies suggest that there are sex- and age-dependent differences in peripheral autonomic control, however,
Autor:
Hussien Rizk, Mohammed Hassan, Karim Said, Marwa Sayed Meshaal, Mervat Gaber El Anani, Dina Labib, Said Abd Al Aziz, Mohammed Hosny, Amani El-Kholy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0201459 (2018)
PLoS ONE, Vol 13, Iss 8, p e0203103 (2018)
PLoS ONE, Vol 13, Iss 11, p e0208350 (2018)
PLoS ONE, Vol 13, Iss 8, p e0201459 (2018)
PLoS ONE, Vol 13, Iss 8, p e0203103 (2018)
PLoS ONE, Vol 13, Iss 11, p e0208350 (2018)
Background Fungal Endocarditis (FE), a relatively rare disease, has a high rate of mortality and is associated with multiple morbidities. Aspergillus endocarditis (AE) is severe form of FE. Incidence of AE has increased and is expected to rise due to
Autor:
Carlo Franchini, Antonio Rosato, Giuseppe Fracchiolla, Alessia Carocci, Antonio Carrieri, Maria Lisa Clodoveo, Alessia Catalano, Giuseppe Carbonara, Filomena Corbo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0200902 (2018)
PLoS ONE, Vol 13, Iss 8, p e0200902 (2018)
Mentha piperita L. essential oil (EO) is employed for external use as antipruritic, astringent, rubefacient and antiseptic. Several studies demonstrated its significant antiviral, antifungal and antibacterial properties. The aim of this work is the s