Zobrazeno 31 - 40
of 668
pro vyhledávání: ''
Autor:
Simone L. Reynolds, Malcolm K. Jones, Nicolas Ortonne, Katja Fischer, Deepani D. Fernando, Bernard Cribier, Gunter Hartel
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008997 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008997 (2021)
Background Scabies, a highly contagious skin disease affecting more than 200 million people worldwide at any time, is caused by the parasitic mite Sarcoptes scabiei. In the absence of molecular markers, diagnosis requires experience making surveillan
Autor:
Carol J. Cardona, Menghuai Sun, Kunlong Yan, Jiao Xing, Zheng Xing, Zhao-jun Duan, Yu Jin, Chunyang Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0245529 (2021)
PLoS ONE, Vol 16, Iss 1, p e0245529 (2021)
Enterovirus A71 (EV-A71) has emerged as a clinically important neurotropic virus following poliovirus eradication. Recent studies have shown that human tonsillar epithelial cell lines (UT-SCC-60A and UT-SCC-60B) were susceptible to EV-A71, suggesting
Autor:
Yang Xiaowen, Guozhong Tian, Tonglei Wu, Wenxiao Liu, Dongri Piao, Hai Jiang, Qingmin Wu, Hongyan Zhao
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008888 (2020)
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008888 (2020)
Brucella spp. are facultative intracellular pathogens that can persistently colonize host cells and cause the zoonosis- brucellosis. The WHO recommended a treatment for brucellosis that involves a combination of doxycycline, rifampicin, or streptomyc
Autor:
Pratchakan Chaiyachat, Ditthawat Nonghanphithak, Kiatichai Faksri, Angkana Chaiprasert, Wipa Reechaipichitkul, Orawee Kaewprasert
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244829 (2020)
PLoS ONE, Vol 15, Iss 12, p e0244829 (2020)
Drug resistance (DR) remains a major challenge for tuberculosis (TB) control. Whole-genome sequencing (WGS) provides the highest genetic resolution for genotypic drug-susceptibility tests (DST). We compared DST profiles of 60 Mycobacterium tuberculos
Autor:
A. Abakar Mahamat, N. Mathé, Roger Faroux, R. Boustany, P. Soulié, L. Moreau, Isabelle Baumgaertner, R. Hervé, J. M. Phelip, D. Smith, J. M. Bons, L. Vazquez, Laurent Miglianico, Eric Francois, Rosine Guimbaud, Laurent Mineur, Louis-Marie Dourthe, A. L. Villing, S. Remy, E. Achille, N. Bonichon, Carine Plassot, I. Rabbia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243997 (2020)
PLoS ONE, Vol 15, Iss 12, p e0243997 (2020)
Background Cetuximab improves progression-free survival (PFS) and overall survival (OS) in patients with KRAS wild type (wt) metastatic colorectal cancer (mCRC). Few data are available on factors impacting both efficacy and compliance to cetuximab tr
Autor:
Constance Schultsz, Le thi Ngoc Kim, Thai Dang Khoa, Pham Quynh Vi, H. Rogier van Doorn, Juliet E. Bryant, James Campbell, Pham Nguyen Phuong, Vu Thi Ty Hang, Nguyen Thi Ngoc, Thomas Pouplin, Christopher M. Parry, Nguyen Thi Thuy Chinh B’Krong, Nguyen Thi Hong Tham, Huynh Duy Khuong, Nguyen Ngoc Hong Phuc, Phung Khanh Lam, Menno D. de Jong, Doan Van Khanh, Nguyen Hanh Uyen, Le Binh Bao Tinh, Nguyen Thanh Hung, Stephen Baker, Pham Van Toi, Heiman F. L. Wertheim, Ngo Ngoc Quang Minh, Le Minh Qui, Le Thi Minh Vien
Publikováno v:
PLoS ONE, 15(11 November):e0241760. Public Library of Science
PLoS ONE
PLoS One, 15
PLoS One, 15, 11
PLOS ONE
PLoS ONE, Vol 15, Iss 11, p e0241760 (2020)
PLoS ONE
PLoS One, 15
PLoS One, 15, 11
PLOS ONE
PLoS ONE, Vol 15, Iss 11, p e0241760 (2020)
Background and objectives Treatment guidelines do not recommend antibiotic use for acute respiratory infections (ARI), except for streptococcal pharyngitis/tonsillitis and pneumonia. However, antibiotics are prescribed frequently for children with AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c74af8c582c236ed5cba4da1babaa0
https://archive.lstmed.ac.uk/16226/1/journal.pone.0241760.pdf
https://archive.lstmed.ac.uk/16226/1/journal.pone.0241760.pdf
Autor:
Christine S. Peters, Matthew R. Bersi, Cynthia R. Clark, J. Ethan Joll, W. David Merryman, Michael A. Raddatz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexp
Autor:
Megan A Palmer, Khalidah Ibraheem, Myria Ioannou, Andrew Collett, Michael Peake, Christopher Dunnill, Nikolaos T. Georgopoulos, Adrian Smith
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
Chemotherapy-induced alopecia (CIA) represents the most distressing side-effect for cancer patients. Scalp cooling is currently the only treatment to combat CIA, yet little is known about its cytoprotective effects in human hair follicles (HF). We ha
Autor:
Fois, Adrien, Boucher-Lafleur, Anne-Marie, Thompson Legault, Julie, Renaud, Christian, Morin, Charles, Des Rosiers, Christine, Coderre, Lise, Laprise, Catherine, Lesage, Sylvie, LSFC Consortium
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0239860 (2020)
PLoS ONE, Vol 15, Iss 10, p e0239860 (2020)
Leigh Syndrome French Canadian (LSFC) is a rare autosomal recessive metabolic disorder characterized by severe lactic acidosis crises and early mortality. LSFC patients carry mutations in the Leucine Rich Pentatricopeptide Repeat Containing (LRPPRC)
Autor:
Isabel S. Shiratsubaki, Ariel Mariano Silber, Jair L. Siqueira-Neto, Bernhard O. Palsson, Rodolpho Ornitz Oliveira Souza, Xin Fang
Publikováno v:
PLoS Neglected Tropical Diseases
Shiratsubaki, I S, Fang, X, Souza, R O O, Palsson, B O, Silber, A M & Siqueira-Neto, J L 2020, ' Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi ', PLOS Neglected Tropical Diseases, vol. 14, no. 10, e0008728 . https://doi.org/10.1371/journal.pntd.0008728
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008728 (2020)
PLoS neglected tropical diseases, vol 14, iss 10
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Shiratsubaki, I S, Fang, X, Souza, R O O, Palsson, B O, Silber, A M & Siqueira-Neto, J L 2020, ' Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi ', PLOS Neglected Tropical Diseases, vol. 14, no. 10, e0008728 . https://doi.org/10.1371/journal.pntd.0008728
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008728 (2020)
PLoS neglected tropical diseases, vol 14, iss 10
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Chagas disease is a neglected tropical disease and a leading cause of heart failure in Latin America caused by a protozoan called Trypanosoma cruzi. This parasite presents a complex multi-stage life cycle. Anti-Chagas drugs currently available are li