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Correction: Phenylephrine induces relaxation of longitudinal strips from small arteries of goat legs
Autor:
Alen Major Venis, Sathya Subramani, Soosai Manickam Amirtham, Kawin Padmaja Marconi, Renu Raj, Bhavithra Bharathi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
Alpha adrenergic stimulation is known to produce vasoconstriction. We have earlier shown that, in spiral strips of small arteries Phenylephrine (PE) caused vasorelaxation under high nitric oxide (NO) environment. However on further experimentation it
Autor:
Pan Xiaoké, Amandeep K. Sandhu, Jurjan Aman, Etto C. Eringa, Camiel V. J. Box, Geesje M. Dallinga-Thie, Alexander H. Turaihi
Publikováno v:
PLOS ONE, 16(7):0250442. Public Library of Science
PLoS ONE, 16(7 July):e0250442. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0250442 (2021)
Box, C V J, Sandhu, A K, Turaihi, A H, Xiaoke, P, Dallinga-Thie, G, Aman, J & Eringa, E C 2021, ' Effects of imatinib on vascular insulin sensitivity and free fatty acid transport in early weight gain ', PLoS ONE, vol. 16, no. 7 . https://doi.org/10.1371/journal.pone.0250442
PLoS ONE, 16(7). Public Library of Science
PLoS ONE, 16(7 July):e0250442. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0250442 (2021)
Box, C V J, Sandhu, A K, Turaihi, A H, Xiaoke, P, Dallinga-Thie, G, Aman, J & Eringa, E C 2021, ' Effects of imatinib on vascular insulin sensitivity and free fatty acid transport in early weight gain ', PLoS ONE, vol. 16, no. 7 . https://doi.org/10.1371/journal.pone.0250442
PLoS ONE, 16(7). Public Library of Science
Background Vascular endothelial dysfunction is an essential part of the pathophysiology of type 2 diabetes and its complications. In type 2 diabetes, endothelial dysfunction is characterized by reduced insulin signaling and increased transendothelial
Autor:
Pieter Steenhuis, Thi Dinh La, Zhanna Gurenko, Hsin Ya Yang, Roslyn Rivkah Isseroff, Aaron M. Glucksman
Publikováno v:
PLoS ONE
PloS one, vol 16, iss 7
PLoS ONE, Vol 16, Iss 7, p e0253139 (2021)
PloS one, vol 16, iss 7
PLoS ONE, Vol 16, Iss 7, p e0253139 (2021)
Keratinocyte migration into skin wounds is the step of the healing process that correlates with the wound closure rate. Keratinocyte migration, and wound epithelialization are decreased when beta 2-adrenergic receptors (B2AR) are activated by 1 μM e
Autor:
J. P. Jones, William Parker, Caroline J. Smith, Zacharoula Konsoula, John Poulton, Jasmine Cendejas Hernandez, Navneet Suda
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253543 (2021)
PLoS ONE, Vol 16, Iss 6, p e0253543 (2021)
Based on several lines of evidence, numerous investigators have suggested that acetaminophen exposure during early development can induce neurological disorders. We had previously postulated that acetaminophen exposure early in life, if combined with
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 6, p e1009145 (2021)
PLoS computational biology, vol 17, iss 6
PLoS Computational Biology, Vol 17, Iss 6, p e1009145 (2021)
PLoS computational biology, vol 17, iss 6
State-dependent sodium channel blockers are often prescribed to treat cardiac arrhythmias, but many sodium channel blockers are known to have pro-arrhythmic side effects. While the anti and proarrhythmic potential of a sodium channel blocker is thoug
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249344 (2021)
PLoS ONE, Vol 16, Iss 4, p e0249344 (2021)
Purpose To examine the effect of prolactin (PRL) on human corneal stromal fibroblasts (CSFs), derived from healthy individuals and from keratoconus (KC) patients, in vitro, specifically assessing physiological and elevated PRL concentrations as appar
Autor:
Atsuo Itakura, Satoru Takeda, Kazuko Saeki, Shintaro Makino, Takehiko Yokomizo, Mai Ohba, Nanase Takahashi, Hiroki Fujii, Masaya Takahashi, Toshiaki Okuno
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0250638 (2021)
PLoS ONE, Vol 16, Iss 4, p e0250638 (2021)
Prostaglandin E2 (PGE2) is known to have important roles in labor, but the detailed mechanism underlying the spontaneous human labor remains unknown. Here, we examined the involvement of prostaglandin biosynthetic enzymes and transporter in the accum
Autor:
Robert N. Kelsh, Jennifer P Owen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0246504 (2021)
PLoS ONE, Vol 16, Iss 3, p e0246504 (2021)
Zebrafish are frequently used as a means to investigate development. These studies increasingly require repeated anaesthesia of zebrafish during juvenile (i.e. metamorphic) stages. The effects of anaesthesia during this time remain poorly studied. Th
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246375 (2021)
PLoS ONE, Vol 16, Iss 2, p e0246375 (2021)
Prostaglandin E2(PGE2)-induced coughsin vivoand vagal nerve depolarizationin vitroare inhibited by systemic and local administration of prostaglandin EP3 receptor (L-798106) and TRPV1 antagonists (JNJ 17203212). These results indicate a modulating ef
Autor:
S. J. Van Schyndel, J. Rousseau, B. Mion, O. Bogado Pascottini, J. F. W. Sprícigo, J. S. Weese, Stephen J. LeBlanc
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0233943 (2021)
PLOS ONE
PLoS ONE, Vol 16, Iss 2, p e0233943 (2021)
PLOS ONE
This study evaluated the effects of treatment with meloxicam (a non-steroidal anti-inflammatory drug), parity, and blood progesterone concentration on the dynamics of the uterine microbiome of clinically healthy postpartum dairy cows. Seven primiparo