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Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0247714 (2021)
PLoS ONE, Vol 16, Iss 4, p e0247714 (2021)
Optimal vancomycin exposure is important to minimize treatment failure of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. We aimed to analyze the impact of initial vancomycin pharmacokinetic/pharmacodynamic (PK/PD) parameters, includin
Autor:
S. J. Van Schyndel, J. Rousseau, B. Mion, O. Bogado Pascottini, J. F. W. Sprícigo, J. S. Weese, Stephen J. LeBlanc
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0233943 (2021)
PLOS ONE
PLoS ONE, Vol 16, Iss 2, p e0233943 (2021)
PLOS ONE
This study evaluated the effects of treatment with meloxicam (a non-steroidal anti-inflammatory drug), parity, and blood progesterone concentration on the dynamics of the uterine microbiome of clinically healthy postpartum dairy cows. Seven primiparo
Autor:
Martin Onyango, Julius Kiwanuka, Yunia Mayanja, Jonathan Kitonsa, Abu-Baker Ggayi, Yofesi Nikweri, Freddie Kibengo, Rebecca N Nsubuga, Zacchaeus Anywaine, Jeremy N. Day, Pontiano Kaleebu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008823 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Globally, early initiation of antiretroviral therapy for HIV led to a reduction in the estimated mortality from cryptococcal meningitis (CCM) from 624,700 in 2009 to 181,100 in 2014. However, CCM remains one of the leading causes of mortality among H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acc9c9e850dbda5dfd93f7c27168fe6
https://doi.org/10.1371/journal.pntd.0008823
https://doi.org/10.1371/journal.pntd.0008823
Autor:
Yemisi Dorcas Obafemi, Akinniyi Paul Akinduti, Joshua Adekunle Osiyemi, Adewale Gideon Adeyemi, Oluwaseun Ejilude, Temitope Temitayo Banjo, Maged El-Ashker, Patrick Omoregie Isibor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247013 (2021)
PLoS ONE, Vol 16, Iss 2, p e0247013 (2021)
Spread of genetically diverse Staphylococcus aureus characterized with multi-antibiotic resistance and regulated by high level agr functionalities in several communities in southwest Nigeria was investigated and evaluated for infection control. Staph
Autor:
Pradnya Dilip Chandanshive, Rashmi Ranjan Mohanty, Shree Ram Singh, Biswa Mohan Padhy, Somen Kumar Pradhan, Prasanta Raghab Mohapatra, Priyamadhaba Behera, Ravikumar S R, Arvind Kumar Singh, Binod Kumar Patro, Gitanjali Batmanabane, Shakti Kumar Bal, Siva Santosh Kumar Pentapati
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247163 (2021)
PLoS ONE, Vol 16, Iss 2, p e0247163 (2021)
Background Ivermectin is one among several potential drugs explored for its therapeutic and preventive role in SARS-CoV-2 infection. The study was aimed to explore the association between ivermectin prophylaxis and the development of SARS-CoV-2 infec
Autor:
Per Damkier, Quentin Frederik Gronau, Jannik Helweg-Larsen, Oliver J. Hulme, Christopher Fugl Madelung, Eric-Jan Wagenmakers, Thomas Benfield, Kristoffer Hougaard Madsen, Hartwig R. Siebner
Publikováno v:
Hulme, O J, Wagenmakers, E J, Damkier, P, Madelung, C F, Siebner, H R, Helweg-Larsen, J, Gronau, Q F, Benfield, T L & Madsen, K H 2021, ' A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19 ', PLOS ONE, vol. 16, no. 2, e0245048 . https://doi.org/10.1371/journal.pone.0245048
PLoS ONE
Hulme, O J, Wagenmakers, E J, Damkier, P, Madelung, C F, Siebner, H R, Helweg-Larsen, J, Gronau, Q F, Benfield, T L & Madsen, K H 2021, ' A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19 ', PLoS ONE, vol. 16, no. 2 February, e0245048 . https://doi.org/10.1371/journal.pone.0245048
Hulme, O J, Wagenmakers, E J, Damkier, P, Madelung, C F, Siebner, H R, Helweg-Larsen, J, Gronau, Q F, Benfield, T L & Madsen, K H 2021, ' A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19 ', PLOS ONE, vol. 16, no. 2 February, e0245048 . https://doi.org/10.1371/journal.pone.0245048
PLoS ONE, Vol 16, Iss 2, p e0245048 (2021)
PLoS ONE, 16(2):e0245048. Public Library of Science
PLoS ONE
Hulme, O J, Wagenmakers, E J, Damkier, P, Madelung, C F, Siebner, H R, Helweg-Larsen, J, Gronau, Q F, Benfield, T L & Madsen, K H 2021, ' A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19 ', PLoS ONE, vol. 16, no. 2 February, e0245048 . https://doi.org/10.1371/journal.pone.0245048
Hulme, O J, Wagenmakers, E J, Damkier, P, Madelung, C F, Siebner, H R, Helweg-Larsen, J, Gronau, Q F, Benfield, T L & Madsen, K H 2021, ' A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19 ', PLOS ONE, vol. 16, no. 2 February, e0245048 . https://doi.org/10.1371/journal.pone.0245048
PLoS ONE, Vol 16, Iss 2, p e0245048 (2021)
PLoS ONE, 16(2):e0245048. Public Library of Science
Gautret and colleagues reported results of a non-randomised open-label case series which examined the effects of hydroxychloroquine and azithromycin on viral load in the upper respiratory tract of Severe acute respiratory syndrome coronavirus 2 (SARS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253b13ad17c451bb52e28ebe2d841d47
https://dare.uva.nl/personal/pure/en/publications/a-bayesian-reanalysis-of-the-effects-of-hydroxychloroquine-and-azithromycin-on-viral-carriage-in-patients-with-covid19(74398772-c521-44a7-bb87-5778cb961309).html
https://dare.uva.nl/personal/pure/en/publications/a-bayesian-reanalysis-of-the-effects-of-hydroxychloroquine-and-azithromycin-on-viral-carriage-in-patients-with-covid19(74398772-c521-44a7-bb87-5778cb961309).html
Autor:
David W. Denning, Christophe Hennequin, Michel Develoux, Fructueux Modeste Amona, Donatien Moukassa
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 2021, 15 (5), pp.e0009318. ⟨10.1371/journal.pntd.0009318⟩
PLoS Neglected Tropical Diseases, Public Library of Science, 2021, 15 (5), pp.e0009318. ⟨10.1371/journal.pntd.0009318⟩
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009318 (2021)
PLoS Neglected Tropical Diseases, 2021, 15 (5), pp.e0009318. ⟨10.1371/journal.pntd.0009318⟩
PLoS Neglected Tropical Diseases, Public Library of Science, 2021, 15 (5), pp.e0009318. ⟨10.1371/journal.pntd.0009318⟩
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009318 (2021)
The Republic of Congo (RoC) is one of the African countries with the most histoplasmosis cases reported. This review summarizes the current status regarding epidemiology, diagnostic tools, and treatment of histoplasmosis in the RoC. A computerized se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27482f53b90d2e9ea1cd093f9a3a3c66
http://hdl.handle.net/20.500.12278/29124
http://hdl.handle.net/20.500.12278/29124
Autor:
Yang Xiaowen, Guozhong Tian, Tonglei Wu, Wenxiao Liu, Dongri Piao, Hai Jiang, Qingmin Wu, Hongyan Zhao
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008888 (2020)
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008888 (2020)
Brucella spp. are facultative intracellular pathogens that can persistently colonize host cells and cause the zoonosis- brucellosis. The WHO recommended a treatment for brucellosis that involves a combination of doxycycline, rifampicin, or streptomyc
Autor:
Constance Schultsz, Le thi Ngoc Kim, Thai Dang Khoa, Pham Quynh Vi, H. Rogier van Doorn, Juliet E. Bryant, James Campbell, Pham Nguyen Phuong, Vu Thi Ty Hang, Nguyen Thi Ngoc, Thomas Pouplin, Christopher M. Parry, Nguyen Thi Thuy Chinh B’Krong, Nguyen Thi Hong Tham, Huynh Duy Khuong, Nguyen Ngoc Hong Phuc, Phung Khanh Lam, Menno D. de Jong, Doan Van Khanh, Nguyen Hanh Uyen, Le Binh Bao Tinh, Nguyen Thanh Hung, Stephen Baker, Pham Van Toi, Heiman F. L. Wertheim, Ngo Ngoc Quang Minh, Le Minh Qui, Le Thi Minh Vien
Publikováno v:
PLoS ONE, 15(11 November):e0241760. Public Library of Science
PLoS ONE
PLoS One, 15
PLoS One, 15, 11
PLOS ONE
PLoS ONE, Vol 15, Iss 11, p e0241760 (2020)
PLoS ONE
PLoS One, 15
PLoS One, 15, 11
PLOS ONE
PLoS ONE, Vol 15, Iss 11, p e0241760 (2020)
Background and objectives Treatment guidelines do not recommend antibiotic use for acute respiratory infections (ARI), except for streptococcal pharyngitis/tonsillitis and pneumonia. However, antibiotics are prescribed frequently for children with AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c74af8c582c236ed5cba4da1babaa0
https://archive.lstmed.ac.uk/16226/1/journal.pone.0241760.pdf
https://archive.lstmed.ac.uk/16226/1/journal.pone.0241760.pdf
Autor:
Fois, Adrien, Boucher-Lafleur, Anne-Marie, Thompson Legault, Julie, Renaud, Christian, Morin, Charles, Des Rosiers, Christine, Coderre, Lise, Laprise, Catherine, Lesage, Sylvie, LSFC Consortium
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0239860 (2020)
PLoS ONE, Vol 15, Iss 10, p e0239860 (2020)
Leigh Syndrome French Canadian (LSFC) is a rare autosomal recessive metabolic disorder characterized by severe lactic acidosis crises and early mortality. LSFC patients carry mutations in the Leucine Rich Pentatricopeptide Repeat Containing (LRPPRC)