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Correction: Phenylephrine induces relaxation of longitudinal strips from small arteries of goat legs
Autor:
Alen Major Venis, Sathya Subramani, Soosai Manickam Amirtham, Kawin Padmaja Marconi, Renu Raj, Bhavithra Bharathi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
PLoS ONE, Vol 15, Iss 3, p e0227316 (2020)
Alpha adrenergic stimulation is known to produce vasoconstriction. We have earlier shown that, in spiral strips of small arteries Phenylephrine (PE) caused vasorelaxation under high nitric oxide (NO) environment. However on further experimentation it
Autor:
Pieter Steenhuis, Thi Dinh La, Zhanna Gurenko, Hsin Ya Yang, Roslyn Rivkah Isseroff, Aaron M. Glucksman
Publikováno v:
PLoS ONE
PloS one, vol 16, iss 7
PLoS ONE, Vol 16, Iss 7, p e0253139 (2021)
PloS one, vol 16, iss 7
PLoS ONE, Vol 16, Iss 7, p e0253139 (2021)
Keratinocyte migration into skin wounds is the step of the healing process that correlates with the wound closure rate. Keratinocyte migration, and wound epithelialization are decreased when beta 2-adrenergic receptors (B2AR) are activated by 1 μM e
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246375 (2021)
PLoS ONE, Vol 16, Iss 2, p e0246375 (2021)
Prostaglandin E2(PGE2)-induced coughsin vivoand vagal nerve depolarizationin vitroare inhibited by systemic and local administration of prostaglandin EP3 receptor (L-798106) and TRPV1 antagonists (JNJ 17203212). These results indicate a modulating ef
Autor:
Carol J. Cardona, Menghuai Sun, Kunlong Yan, Jiao Xing, Zheng Xing, Zhao-jun Duan, Yu Jin, Chunyang Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0245529 (2021)
PLoS ONE, Vol 16, Iss 1, p e0245529 (2021)
Enterovirus A71 (EV-A71) has emerged as a clinically important neurotropic virus following poliovirus eradication. Recent studies have shown that human tonsillar epithelial cell lines (UT-SCC-60A and UT-SCC-60B) were susceptible to EV-A71, suggesting
Autor:
Christine S. Peters, Matthew R. Bersi, Cynthia R. Clark, J. Ethan Joll, W. David Merryman, Michael A. Raddatz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexp
Autor:
Megan A Palmer, Khalidah Ibraheem, Myria Ioannou, Andrew Collett, Michael Peake, Christopher Dunnill, Nikolaos T. Georgopoulos, Adrian Smith
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240454 (2020)
Chemotherapy-induced alopecia (CIA) represents the most distressing side-effect for cancer patients. Scalp cooling is currently the only treatment to combat CIA, yet little is known about its cytoprotective effects in human hair follicles (HF). We ha
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238174 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238174 (2020)
Burkholderia pseudomallei is a facultative intracellular pathogen and the causative agent of melioidosis, a potentially life-threatening disease endemic in Southeast Asia and Northern Australia. Treatment of melioidosis is a long and costly process a
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238208 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238208 (2020)
IntroductionPeripheral nerve injury (PNI) often leads to significant functional loss in patients and poses a challenge to physicians since treatment options for improving functional outcomes are limited. Recent studies suggest that erythropoietin and
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
PLoS ONE, Vol 15, Iss 9 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238184 (2020)
Pneumocystis pneumonia (PCP) is an opportunistic and potentially life-threatening infection of AIDS patients caused by the fungus Pneumocystis jirovecii (P. jirovecii). Trimethoprim-sulfamethoxazole (TMP-SMX) is the most commonly used drug combinatio
Autor:
Céline Crauste, Patrick Fourquet, Thierry Durand, Abdeldjalil Madani, Stéphane Canaan, Luc Camoin, Alexandre Guy, Stéphane Audebert, Ivy Mallick, Jean-François Cavalier
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238178 (2020)
PLoS ONE, 2020, 15 (9), pp.e0238178. ⟨10.1371/journal.pone.0238178⟩
PLoS ONE, Public Library of Science, 2020, 15 (9), pp.e0238178. ⟨10.1371/journal.pone.0238178⟩
PLoS ONE, Vol 15, Iss 9, p e0238178 (2020)
PLoS ONE, 2020, 15 (9), pp.e0238178. ⟨10.1371/journal.pone.0238178⟩
PLoS ONE, Public Library of Science, 2020, 15 (9), pp.e0238178. ⟨10.1371/journal.pone.0238178⟩
International audience; Mycobacterium abscessus (M. abscessus), a rapidly growing mycobacterium, is an emergent opportunistic pathogen responsible for chronic bronchopulmonary infections in individuals with respiratory diseases such as cystic fibrosi