Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
William Guzman, Janielle P. Maynard, Karen S. Sfanos, Alan K. Meeker, Eva Shrestha, Jonathan Coulter, Sarah E. Ernst, Christopher M. Heaphy, Busra Ozbek, Megan M. Hess, Luke Mummert, Michael C. Haffner, Angelo M. De Marzo
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Prostate adenocarcinoma is the second most commonly diagnosed cancer in men worldwide, and the initiating factors are unknown. Oncogenic TMPRSS2:ERG (ERG+) gene fusions are facilitated by DNA breaks and occur in up to 50% of prostate cancers. Infecti
Autor:
Angelo M. De Marzo, Susan L. Dalrymple, John T. Isaacs, Lizamma Antony, Donald J. Vander Griend, Ivan V. Litvinov, Charles G. Drake
Publikováno v:
Proceedings of the National Academy of Sciences. 103:15085-15090
Androgen receptor (AR) protein expression and function are critical for survival and proliferation of androgen-sensitive (AS) prostate cancer cells. Besides its ability to function as a transcription factor, experimental observations suggest that AR