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Autor:
Ana I. Rodriguez-Perez, Rita Valenzuela, Carmen M. Labandeira, Jose L. Labandeira-Garcia, Maria A. Pedrosa, Gemma Navarro, Pablo Garrido-Gil, Rafael Franco
Publikováno v:
Clinical Science (London, England : 1979)
Clinical Science
Clinical Science
The key link between renin–angiotensin system (RAS) and COVID-19 is ACE2 (angiotensin-converting enzyme 2), which acts as a double-edged sword, because ACE2 increases the tissue anti-inflammatory response but it is also the entry receptor for the v
Autor:
Bin Dong, Longyun Peng, Jun Liu, Yi Li, Chen Liu, Yu Sun, Yugang Dong, Ruicong Xue, Huiling Huang
Publikováno v:
Bioscience Reports
Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional secreted protein that can be induced by fasting, hypoxia and glucocorticoids. ANGPTL4 has been associated with a variety of diseases; however, the role of ANGPTL4 in cardiac hypertrophy remai
Publikováno v:
Bioscience Reports
Peritonitis is still a major cause of the death in peritoneal dialysis (PD) patients despite the significant decline of the peritonitis rates in recent years. The present study is designed to evaluate the therapeutic potential of peroxisome prolifera
Publikováno v:
Bioscience Reports
Chronic heart failure (CHF) is the end-stage of many cardiovascular diseases and severely affects the patients’ lifespan. Inhibiting ventricular remodeling is thus a primary treatment target for CHF patients. Astragaloside IV (AS-IV) can improve ca
Publikováno v:
Biochemical Journal. 450:303-309
In yeast two-hybrid screening, protein 4.1N, a scaffolding protein, was identified as a binding partner of the α7 ACh (acetylcholine) receptor. For rat hippocampal slices, the linoleic acid derivative DCP-LA {8-[2-(2-pentyl-cyclopropylmethyl)-cyclop
Autor:
D. Susic
Publikováno v:
Biochemical Society Transactions. 35:853-856
Fibrillar proteins, such as collagens type I and III, and elastin are components of the extracellular matrix. They form an intricate widespread network that provides a basis for maintaining the physical structure of the heart and vessels and also pla
Autor:
C Missale, C Fiorentini
Publikováno v:
Biochemical Society Transactions. 32:1025-1028
In the striatum, dopamine D1R (D1 receptor) activation potentiates NMDA (N-methyl-D-aspartate) transmission and is required for NMDA-mediated long-term potentiation at corticostriatal synapses. By using a combination of co-immunoprecipitation, pull-o
Publikováno v:
Clinical Science. 105:383-391
Evidence from a recent study indicates that glucocorticoids (GCs) mediate skeletal muscle proteolysis during sepsis via the GC receptor (GR) pathway. Attempts to identify the mechanisms regulating GR gene expression in skeletal muscle during sepsis h
Publikováno v:
Biochemical Journal. 344:487-493
Major biochemical activities of the pineal gland include melatonin biosynthesis and 12-lipoxygenation. In this paper, we provide evidence in vivo that melatonin regulates 12-lipoxygenation via 12-lipoxygenase (LOX) expression. The relationship betwee
Autor:
Matthew C. Wright
Publikováno v:
Biochemical Society Transactions. 27:387-391