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Autor:
Jacek J. Klawe, Christian Thoma, Christopher P. Day, Michael I. Trenell, Paweł Zalewski, Djordje G. Jakovljevic, Julia L. Newton, Kate Hallsworth
Publikováno v:
Clinical Science; Vol 125
Autonomic dysfunction has been reported in patients with NAFLD (non-alcoholic fatty liver disease) and is associated with clinical presentations. To date, there are no therapies to improve autonomic regulation in people with NAFLD. The present study
Autor:
James Wong, Stephen B. Harrap, Dominica Zentner, Leeanne Grigg, Shaun P. Brennecke, Moira du Plessis
Publikováno v:
Clinical Science. 116:599-606
The aim of the present study was to undertake a longitudinal study of systolic and diastolic cardiac function during normal pregnancy. At a median of 16 weeks of gestation, 100 primiparous women underwent echocardiography, including tissue Doppler im
Publikováno v:
Clinical Science. 116:497-505
PH (pulmonary hypertension) often complicates the disease course of patients with COPD (chronic obstructive pulmonary disease) and is an indication of a worse prognosis. In the present study, we assessed whether pravastatin administration was effecti
Autor:
Öivind Mathillas, Ted Ivarsson, Finn-David Nielsen, Sinsia A. Gao, Peter Friberg, Jan Carlström, Susanne Ljungman, Ulf Strömbom, Mats I. Johansson, Marita Annerstedt, Göran Bergström, Gert Jensen
Publikováno v:
Clinical Science. 107:583-588
Patients with CRF (chronic renal failure) are at increased risk of cardiovascular diseases, and 60% of cardiovascular mortality in CRF is attributed to sudden death. Various abnormalities in myocardial repolarization are associated with the risk of v
Autor:
Alan G. Fraser, Ann C. Tweddel, Michael R. Stephens, Dragos Vinereanu, N Florescu, Nicholas Sculthorpe
Publikováno v:
Clinical Science. 103:249-257
In order to determine left ventricular global and regional myocardial functional reserve in endurance-trained and strength-trained athletes, and to identify predictors of exercise capacity, we studied 18 endurance-trained and 11 strength-trained athl
Publikováno v:
Clinical Science. 102:31-38
The purpose of the present study was to define the influence of age and exercise training on the heart rate (HR) dynamic response (i.e. kinetics) to sinusoidal work. A total of 63 healthy subjects (31 men and 32 women; age range 19-69 years) underwen
Autor:
Hiroshi Asakawa, Shigeo Horinaka, Noriaki Tsuchiya, Takeshi Suzuki, Hiroaki Matsuoka, Toshio Nishikimi, Hiroshi Yagi, Yusuke Tsubokou, Akihisa Yabe, Suomi Hara, Kenji Kangawa
Publikováno v:
Clinical Science. 100:117-126
Adrenomedullin (AM) has vasodilatory, diuretic and natriuretic actions. Two molecular forms of AM circulate in human plasma: an active, mature form of AM (AM-m) and an intermediate, inactive, glycine-extended form of AM (AM-Gly). In the present study
Autor:
Hiroaki Matsuoka, Kenji Kangawa, Seiki Nagata, Hisayuki Matsuo, Fumiki Yoshihara, Noritoshi Nagaya, Tatsuya Sasaki, Takeshi Horio, Toshio Nishikimi
Publikováno v:
Clinical Science. 100:61-66
Adrenomedullin (AM), a novel hypotensive peptide, preferentially dilates pulmonary vessels rather than systemic vessels. This suggests the possibility that AM is a circulating hormone which participates in regulation of the pulmonary circulation. A r
Publikováno v:
Clinical Science. 99:27-35
In the failing human myocardium, both impaired calcium homoeostasis and alterations in the levels of contractile proteins have been observed, which may be responsible for reduced contractility as well as diastolic dysfunction. In addition, levels of
Autor:
James D. Cameron, Barry P McGrath, Louise Shiel, Yu-Lu Liang, Anthony M. Dart, Dimitra Kotsopoulos, Helena J. Teede
Publikováno v:
Clinical Science. 95:669-679
1. Repeatability of measurements of arterial compliance and flow-mediated dilation of the brachial artery has been infrequently reported, despite increasing use in interventional and risk-factor modification studies. Furthermore, little is known abou