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Publikováno v:
Brøndum, E T, Kold-Petersen, H, Nilsson, H, Flyvbjerg, A & Aalkjaer, C 2008, ' Increased contractility to noradrenaline and normal endothelial function in mesenteric small arteries from the goto-kakizaki rat model of type 2 diabetes ', Journal of Physiological Sciences, vol. 58, no. 5, pp. 333-9 . https://doi.org/10.2170/physiolsci.RP010108
Udgivelsesdato: 2008-Oct Type 2 diabetes is associated with many circulatory manifestations, including alteration in endothelial function and hypertension. In this study we investigate the morphology and contractile response as well as the endothelia
Publikováno v:
The Journal of Physiological Sciences. 58:249-261
We investigated the pivotal roles of glucose and its transporter in the regulation of mechanical activity of isolated rat thoracic ducts and then examined whether mitochondrial ATP-sensitive K(+) channels (mitoK(ATP)) are involved in those responses.
Publikováno v:
The Journal of Physiological Sciences. 58:263-270
In urethane-anesthetized, artificially ventilated rats, alterations in dorsal spinal cord blood flow (SCBF) at the L4-6 level were measured with laser Doppler flowmetry in response to noxious mechanical cutaneous stimulation (pinching) of either a fo
Autor:
Sungtae Koo, Boram Sun, Sun Kwang Kim, Byung-Il Min, Jung Hyuk Park, Hyunsu Bae, Ha Neul Kim, Sun Mi Choi
Publikováno v:
The Journal of Physiological Sciences. 58:357-360
This study was performed to examine whether electroacupuncture potentiates the neostigmine-induced antiallodynia in neuropathic pain rats. Although intrathecal neostigmine (0.05, 0.1, and 0.3 microg) dose-dependently relieved cold allodynia, 0.3 micr
Publikováno v:
The Journal of Physiological Sciences. 56:253-257
Walking produced increases in both the extracellular acetylcholine level and regional blood flow in the hippocampus in aged rats 26-29 months old. The present results in aged rats were compared with our previous data in young adult rats (Nakajima et
Publikováno v:
The Journal of Physiological Sciences. 56:449-454
The functional residual capacity (FRC) and airway resistance (R(aw)) of the rat were measured, using a newly designed body plethysmograph (BPG), the inner environment of which was maintained at body temperature and was water-vapor saturated. The subj
Autor:
Ziya Kaygisiz, Nuray Yazihan, Kemal Sayar, Ruhi Uyar, Nilüfer Erkasap, Haluk Ataoglu, Murat Ikizler
Publikováno v:
The Journal of Physiological Sciences. 56:247-251
There is enough evidence that erythropoietin (EPO) may be involved in cardiovascular function. Therefore we have investigated the possible effects of EPO on left ventricular developed pressure, +dP/dt(max), heart rate, tissue cAMP, and nitrite levels
Publikováno v:
The Journal of Physiological Sciences. 56:205-209
To gain more insight into the molecular mechanism of muscle growth and fiber-type transformations, we analyzed the effects of beta(2)-adrenergic agonist clenbuterol (CB) and/or cyclosporin A (CsA), a potent inhibitor of calcineurin (CaN), on the musc
Vasodilatation of the Hindquarters Induced by Antagonism of GABAA Receptors in the Freely Moving Rat
Autor:
Yumi Takemoto
Publikováno v:
The Japanese Journal of Physiology. 55:75-78
An intracisternal injection of the GABA(A) receptor antagonist bicuculline into conscious rats increased arterial pressure and decreased hindquarter resistance. Propranolol attenuated only the resistance response, but ganglionic block abolished both
Publikováno v:
The Japanese Journal of Physiology. 55:331-338
Short-chain fatty acids, such as propionate and acetate, are produced by a bacterial fermentation of carbohydrates in the colonic lumen. We examined the effects of propionate on the frequency and mean amplitude of spontaneous giant contractions (GCs)