Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yuji Suzuki"'
Autor:
Yasuhiko Yamada, Haruko Yokoyama, Yasuhisa Kitagawa, Yuji Suzuki, Shinji Soeda, Kentaro Tokuoka, Masayuki Watanabe
Publikováno v:
YAKUGAKU ZASSHI. 134:545-553
Low-dose aspirin-induced gastrointestinal lesions are becoming an important problem in clinical practice. In our investigation of such adverse effects, we obtained 4 important findings considered useful for physicians, as follows; 1) even when aspiri
Autor:
Haruko Yokoyama, Noriyuki Ikeda, Yuji Suzuki, Shinji Soeda, Yasuhisa Kitagawa, Naoko Ito, Yasuhiko Yamada, Kentaro Tokuoka, Masayuki Watanabe
Publikováno v:
YAKUGAKU ZASSHI. 131:1073-1077
It has been reported that non-steroidal anti-inflammatory drugs (NSAIDs) interact with aspirin to influence its antiplatelet effect. For example, there have been reported that the rate of platelet aggregation inhibition associated with aspirin was si
Autor:
Kentaro Tokuoka, Yasuhisa Kitagawa, Yuji Suzuki, Haruko Yokoyama, Takehiro Yaguchi, Yasuhiko Yamada, Masayuki Watanabe, Hironori Nakamura
Publikováno v:
YAKUGAKU ZASSHI. 131:1085-1094
Aspirin irreversibly inhibits the enzyme cyclooxygenase-1 and depresses the production of thromboxane A(2), and also exerts antiplatelet effects. On the other hand, it also depresses the production of prostaglandin E(2) (PGE(2)) and induces gastroduo
Autor:
Hironori Nakamura, Takehiro Yaguchi, Kentaro Tokuoka, Masayuki Watanabe, Yasuhiko Yamada, Yuji Suzuki, Haruko Yokoyama, Yasuhisa Kitagawa
Publikováno v:
YAKUGAKU ZASSHI. 131:445-452
In this study, we investigated the effect of histamin H₂ receptor antagonist (H₂RA) or proton pump inhibitor (PPI) for the prevention of upper gastrointestinal lesions associated with low-dose aspirin. We carried out a retrospective study of 2811
Autor:
Akira Dobashi, Haruko Yokoyama, Toshiaki Ando, Takeshi Ozeki, Yasuhiko Yamada, Yoshimi Hinohara, Yuji Suzuki, Masayuki Watanabe, Risa Takayanagi
Publikováno v:
YAKUGAKU ZASSHI. 127:2027-2033
We established a network meeting system program and used it to review a prior pharmaceutical practice training session. Pharmacists at Tokai University Hachioji Hospital gave lectures about dispensing and other tasks performed by clinical pharmacists
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:3160-3166
Publikováno v:
Chemical and Pharmaceutical Bulletin. 27:1181-1185
Photolysis of acyl azides (1, 10) in diketene was investigated. Irradiation of a mixture of benzoyl azide (1a) and diketene in dichloromethane gave 1-benzoyl-4-hydroxy-3-pyrrolin-2-one (2a) in 17% yield. Similarly, reaction of diketene with p-anisoyl
Autor:
Hiroshi Takahashi, Yuji Suzuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 31:2895-2898
Reaction de [methoxymethyl-1' methyl-2'] propylimine et d'[hydroxymethyl-1' methyl-2'] propylimine du benzaldehyde avec le bromure d'ethyl-magnesium suivie d'une reaction de N-methylation (iodomethane)
Autor:
Yuji Suzuki, Hiroshi Takahashi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 31:31-40
Optically pure (1S, 1'S)-1-aryl-N-(1'-alkyl-2'-hydroxyethyl)-2-phenylethylamines (13-21) were synthesized from L-alanine, L-leucine, and L-isoleucine via (S)-2-aminoalkanols (1-3) and (E)-(S)-N-(1-alkyl-2-hydroxyethyl) arylmethylideneamines (4-12). O
Autor:
Yuji Suzuki, Hiroshi Takahashi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 31:4295-4299
A chiral hydrazone, (E)-(S)-N'-benzylidene-N, 3-dimethyl-2-hydrazinobutanol (6), was synthesized from (S)-valinol. Compound 6 was reacted with Grignard reagents to give optically pure (2S, 1'S)-N, 3-dimethyl-N'-1'-phenylalkyl-2-hydrazinobutanols (7a