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Relationship Between Serum Potassium, Magnesium, and Calcium in Patients Receiving Cetuximab Therapy
Autor:
Kaito Yamashiro, Atsushi Hirata, Naohito Kawasaki, Takehiro Nakamura, Ryosuke Ota, Fumihiko Ogata
Publikováno v:
BPB Reports. 4:22-26
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1172-1178
The sodium salt of isosteviol (STVNa) is a beyerane diterpene synthesized through acid hydrolysis of stevioside. STVNa improves multiple types of tissue injuries. However, it is not known how isosteviol sodium affects high-fat and high cholesterol di
Publikováno v:
BPB Reports. 3:170-173
Autor:
Masaki Otagiri, Daisuke Iohara, Kazuki Shimoishi, Makoto Anraku, Fumitoshi Hirayama, Sachiko Zingami, Ayako Uto, Toru Maruyama, Daisuke Kadowaki
Publikováno v:
YAKUGAKU ZASSHI. 137:903-908
A high dietary intake of phosphorus is considered to be a significant health threat for hemodialysis (HD) patients. Prescription medications, which might be a major source of phosphorus, is largely unrecognized in Japan. However, the amount of phosph
Autor:
Hiroshi Watanabe, Kazuaki Taguchi, Toru Maruyama, Koji Nishi, Yasunori Iwao, Keishi Yamasaki, Masaki Otagiri, Yu Ishima, Sadaharu Matsushita
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:1813-1817
Human serum albumin (HSA), the most abundant protein in serum, functions as carrier of drugs and contributes to maintaining serum colloid osmotic pressure. We report herein on the preparation of a genetic recombinant HSA, in which domains II and III
Autor:
Shinji Motomura, Shuichi Enomoto, Masashi Ueda, Hiroyuki Yasui, Masayuki Munekane, Shinichiro Kamino, Hiromitsu Haba, Yutaka Yoshikawa
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:510-515
Many zinc (Zn) complexes have been developed as promising oral antidiabetic agents. In vitro assays using adipocytes have demonstrated that the coordination structures of Zn complexes affect the uptake of Zn into cells and have insulinomimetic activi
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 64:1555-1559
Activated carbon (AC) has been widely applied for adsorptive removal of organic contaminants from aqueous phase, but not for ionic pollutants. In this study, nitrogen doped AC was prepared to increase the adsorption capacity of nitrate from water. AC
Autor:
Ruizhuo Ouyang, Yang Yang, Shuang Zhou, Yaoqin Yang, Penghui Cao, Fei Xiong, Xiaoshen Zhang, Yuhao Li, Kai Feng, Yuqing Miao, Huihong Tao, Tianyu Zong, Ning Guo
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 64:1539-1545
6-Mercaptopurine (6-MP) is a clinically important antitumor drug and its commercially available form is provided as monohydrate, belonging to biopharmaceuticals classification system (BCS) class II category. The combination of bismuth(III) (Bi(III))
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:138-142
Previous studies showed an increased prevalence of cataracts in postmenopausal women. In this study, we investigated changes in the levels of calcium ion (Ca(2+)) and interleukin (IL)-18, which are factors in cataract development, in the lenses of ov
Autor:
Takehiko Yasuji, Keiichi Yoshihara, Kazuhiro Sako, Yuuki Kasashima, Noriyuki Namiki, Shinya Uchida
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 64:1304-1309
The objective of this study was to establish the key factor of the lauryl sulfate (LS) salt/complex for sustained release of a hydrophilic drug at various physiological pH levels. Mirabegron is a hydrophilic drug that exhibits pH-dependent solubility