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Publikováno v:
Biological & Pharmaceutical Bulletin. 39:138-142
Previous studies showed an increased prevalence of cataracts in postmenopausal women. In this study, we investigated changes in the levels of calcium ion (Ca(2+)) and interleukin (IL)-18, which are factors in cataract development, in the lenses of ov
Autor:
José Raúl Medina, Adriana Miriam Domínguez-Ramírez, Marcela Hurtado, Alba Jady Delgadillo, Alma Rosa Cortés, Kazuko Aoki
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:1186-1190
The antispasmodic activity of extracts from the aerial parts of Buddleja scordioides and Buddleja perfoliata (family: Scrophulariaceae) was studied on isolated tissue preparations from rabbit and guinea pig intestine. The chloroformic extract from th
Autor:
Toyokichi Yoshizawa, Toshihiro Nohara, Xi Ying Zhao, Motoyuki Nakamura, Fumio Hashimoto, Wen Mei Yan, Yu Ming Chi, Shinobu Sakurada, Junei Kinjo
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:489-493
The oral anti-inflammatory activity of 4,4'-dihydroxy-alpha-truxillic acid (1) was compared with that of two other nonsteroidal anti-inflammatory drugs, loxoprofen sodium (LOX) and diclofenac sodium (DIC). The activity of 1 against the inflammatory p
Autor:
Tokiko Aikawa, Tadashi Ishii, Koki Shigenobu, Ryo-ichi Fujisaki, Yusuke Miyamoto, Yoshino Tanaka, Hikaru Tanaka, Toru Kawanishi, Wataru Hirayama
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:323-326
Effects of Mn2+ on isolated guinea pig ventricular myocardia were examined. In isolated papillary muscles, Mn2+ produced a transient decrease in contractile force followed by a late sustained augmentation. Mn2+ markedly increased the amplitude of pos
Publikováno v:
Biological and Pharmaceutical Bulletin. 23:1357-1362
The in vitro permeation of three diclofenac salts--diclofenac sodium (DFS), diclofenac potassium (DFP) and diclofenac diethylammonium (DFD)-across skin by both passive and iontophoretic transport were investigated. Various skin types were used as the
Autor:
Masayoshi Yamaguchi, Yasuko Hanahisa
Publikováno v:
Biological and Pharmaceutical Bulletin. 22:313-316
Adenosine 5'-triphosphatase (ATPase) plays a role in the process of energy conversion in the controlled hydrolysis of ATP. The effect of Ca2+ -binding protein on ATPase activity in the brain cytosol of rats of different ages was investigated. ATPase
Publikováno v:
Biological and Pharmaceutical Bulletin. 30:585-587
Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyd
Autor:
Syojiro Kyotani, Masahiko Kusunose, Hisashi Mimoto, Masafusa Asai, Yutaka Nishioka, Takashi Hamada, Yusuke Sagara
Publikováno v:
Chemical and Pharmaceutical Bulletin. 39:1518-1521
Cisplatin (CDDP) has attracted attention as a chemotherapeutic agent for the treatment of uterine endometrial carcinoma but causes serious side effects, including renal toxicity. CDDP suppositories containing NaCl at different concentrations were pre
Autor:
Nobuo Ikekawa, Tadashi Eguchi, Shohei Higuchi, Masayoshi Kumegawa, Koji Sumitani, Susumu Otomo
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:1246-1249
A series of analogs of 1 alpha,25-dihydroxyvitamin D3 [1,25-(OH)2D3 (1)] with alkyl substitutions in 26- and 27-positions have been tested for their activity 1) in competing with 1,25-(OH)2D3 for binding to chick intestinal cytosol receptor, 2) in ab
Publikováno v:
Chemical and Pharmaceutical Bulletin. 28:1125-1130
With the aim of developing a dosage form for the treatment of carcinoma colli, stick-like preparations containing bleomycin hydrochloride (BLM), carboquone (CQ), and 5-fluoro-uracil (5-FU) held in a mixture of hydroxypropyl cellulose (HPC) and Carbop