Zobrazeno 1 - 10
of 1 144
pro vyhledávání: ''
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1894-1897
The lusitropic effect of quercetin was examined on isolated ventricular myocardial tissue preparations from normal and streptozotocin-induced diabetic mice. The time required for 90% relaxation of the myocardium, which was prolonged in the diabetic m
Autor:
Takayuki Koga, Jeffrey M. Peters
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1598-1606
Excessive, chronic alcohol consumption can lead to alcoholic liver disease. The etiology of alcoholic liver disease is multifactorial and is influenced by alterations in gene expression and changes in fatty acid metabolism, oxidative stress, and insu
Autor:
Mirai Kawakita, Keisuke Obara, Fumiko Yamaki, Ayana Kawaguchi, Keyue Xu, Guanghan Ou, Haruna Yamashita, Rikako Inaba, Yoshio Tanaka, Kento Yoshioka, Rika Yamaguchi
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1129-1139
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are n-3 polyunsaturated fatty acids (PUFAs), and are abundant in fish oil. These n-3 PUFAs have been reported to improve the lower gastrointestinal (LGI) disorders such as ulcerative colitis
Autor:
Misaki Kojima, Masakuni Degawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1120-1128
We previously reported androgen-dependent sex and breed differences in the amounts of mRNAs of CYP isoforms in the pig liver. To clarify whether there are such sex and breed differences in the kidney, we examined the amounts of several CYP mRNAs in t
Autor:
Tatsuya Kitao, Megumi Yamamoto, Masaki Fukui, Yuma Ito, Shohei Furukawa, Hiroaki Shirahase, Ko Morishita
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:659-668
Peroxisome proliferator-activated receptor γ (PPARγ) modulators are expected to exert anti-diabetic effects without PPARγ-related adverse effects, such as fluid retention, weight gain, and bone loss. The present study showed that the novel tetrazo
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:522-527
Methylmercury (MeHg) exposure during pregnancy is a concern because of its potential health risks to fetuses. Intestinal microbiota has important roles in the decomposition and fecal excretion of MeHg. We investigated the effect of nondigestible sacc
Autor:
Guadalupe Luisa Jimenez-Sánchez, Mariana Segovia-Mendoza, Cristina Lemini, Alejandra Figueroa
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:63-68
BACKGROUND/AIM Hormone replacement therapy during menopause increases the risk of thromboembolic diseases and cancer, so safety alternative therapeutic strategies are needed. 17β-Aminoestrogens are a synthetic estrogens group that possess mild antic
Autor:
Kentaro Tamura, Yukako Kawasaki, Arisa Katsuma, Masami Makimoto, Ayane Mito, Masato Taguchi, Taketoshi Yoshida
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:69-74
The purpose of this study was to clarify the variability of serum concentrations of caffeine (CAF) in preterm infants, and to deliberate on a better explanation for developmental changes of systemic clearance during the neonatal period. Forty-nine se
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1987-1992
Extracellular nucleotides play an important role in the regulation of vascular function, and an abnormal vascular function is an important participant in the development and progression of diabetic vascular complications. The purpose of this study wa
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1810-1813
An elevated plasma homocysteine level is an independent risk factor for cardiovascular diseases, neurological disorders, and pregnancy complications. We recently demonstrated partial lactation failure in cystathionine γ-lyase-deficient (Cth-/-) dam