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Autor:
Asami Mori, Kenji Sakamoto, Yoshihiro Higashi, Tsutomu Nakahara, Kunio Ishii, Kentaro Higashi
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:1586-1592
Resveratrol, which is a polyphenol found in grapes, peanuts, and other plants, has health benefits for various chronic diseases. The aim of the present study was to examine the effect of resveratrol on cataract formation in diabetic rats. Male Wistar
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:2022-2027
Metformin is a biguanaide antidiabetic drug used worldwide, and its effectiveness and benefits have already been established. However, the safety of high doses of metformin in Japanese patients, especially in elderly patients with a decreased renal f
Autor:
Makoto Yamaguchi, Shoko Takai
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:404-408
Inflammation has been implicated in development of the insulin resistance that leads to elevated blood sugar levels associated with type 2 diabetes. It is reported that salsalate, a common non-steroidal anti-inflammatory drug, has been shown to decre
Autor:
Ranjitsinh V. Devkar, Ravirajsinh N. Jadeja, Menaka C. Thounaojam, Ansarullah, A. V. Ramachandran
Publikováno v:
Journal of Health Science. 56:92-98
The present study investigates effect of Sida rhomboidea ROXB .( S. rhomboidea ROXB., SR) on high fat diet (HFD) induced insulin resistance in C57BL/6J mice and the results obtained have been compared with mice fed with rosiglitazone (ROS). Changes i
Autor:
Shaoqiang Lin, Xiaojie Wang, Yan-Xia Lv, Jian Xiao, Wenke Feng, Litai Jin, Keqiong Hu, Lu Cai, Xiaokun Li, Yi Zhang, Yi Tan, Jisheng Ma
Publikováno v:
Biological and Pharmaceutical Bulletin. 33:444-449
Diabetes impairs the expression and function of endogenous growth factors, leading to increased cardiovascular events in diabetic patients. Supplementation of fibroblast growth factors (FGFs) protected the heart from ischemia/reperfusion (I/R)-induce
Publikováno v:
Journal of Health Science. 56:20-30
Diabetes enhances oxidative stress and exacerbates acute ischemic injury. Previous studies have demonstrated that infarct volumes were greater in diabetic animals caused by a transient cerebral ischemia as compared with non-diabetic animals. Ascorbic
Publikováno v:
Biological and Pharmaceutical Bulletin. 32:220-224
Diabetic nephropathy (DN) has become the leading cause of end stage renal failure, and prevention or retardation of DN has become a major goal in biomedical research. In this study, Tanshinone IIA, a component extracted from Salvia miltiorrhiza, was
Autor:
Sathiya Moorthi Perumal, Balu Periamallipatti Muniappan, Murugesan Kandasamy, Periyar Selvam Sellamuthu
Publikováno v:
Journal of Health Science. 55:206-214
The study was undertaken to evaluate the antihyperglycemic potential of mangiferin purified from methanolic root extract of Salacia chinensis (S. chinensis )i nc ontrol and streptozotocin (STZ)-induced diabetic rats. The mangiferin was administered o
Publikováno v:
YAKUGAKU ZASSHI. 128:1699-1705
The present study was designed to investigate a possible role of vanilloid receptors, CGRP and spleen in the induction of diabetes induced hyperalgesia in mice. Tail flick latency, an index of hyperalgesia, was assessed using analgesiometer. Serum ni
Autor:
Coskun Silan
Publikováno v:
Biological and Pharmaceutical Bulletin. 31:897-902
Silan, Coskun/0000-0002-8352-6571; silan, coskun/0000-0002-8352-6571 WOS: 000256182500023 PubMed: 18451515 Deficiency in the vasorelaxant capacity is a result of an oxidative stress in diabetic animals and seems to be an etiological factor of vascula