Zobrazeno 1 - 10
of 372
pro vyhledávání: ''
Publikováno v:
Journal of Health Science. 57:72-77
We previously reported that novel polyselenodithiols are produced along with selenotrisulfide when a thiol (penicillamine) is reacted with selenite (H2SeO3). Here, we report the production of oligoselenodiglutathiones and their suppressive effects on
Publikováno v:
Journal of Health Science. 57:153-163
It is generally known that many psychological factors, such as stress or insomnia, cause mental fatigue. However, the detailed mechanisms underlying mental fatigue have not been clarified. We speculated that mental fatigue may be caused by neuronal b
Autor:
Pazhanichamy Kalailingam, Kumaran Shanmugam, Aiswarya Devi Sekar, Eevera Tamilmani, Jeba Samuel Clement Samuel, Rajendran Kaliaperumal, Manjula Kesavan, Yogha Govindaraju, Priya Gandhirajan
Publikováno v:
JOURNAL OF HEALTH SCIENCE. 57:37-46
In this study, effect of an ethanolic extract from rhizome of Costus igneus were investigated on activity of following enzyme in liver, kidney, pancreas of streptozotocin (STZ) induced diabetic rats: carbohydrate metabolic enzymes such as glucokinase
Publikováno v:
Journal of Health Science. 57:204-209
Manganese (Mn) damages the central nervous system and causes Parkinson's disease (PD)-like syndrome called manganism. Abnormal accumulation of Mn and iron (Fe) is observed in the basal nuclei of patients with PD. Dopamine induces oxidative DNA damage
Autor:
Yasuhiro Uno, Ryo Koizumi, Hiroshi Yamazaki, Kazuhide Iwasaki, Norie Murayama, Chie Emoto, Masahiro Utoh
Publikováno v:
Journal of Health Science. 57:164-170
Cynomolgus monkeys [Macaca fascicularis (mf)] are widely used to determine pharmacokinetics and toxicological potential of many drug candidates as human models in the drug discovery and development. Cytochrome P450s (P450, CYP), one of the most impor
Autor:
Tae Wha Kim, Yoo Sin Park, Dong-Sun Kim, Seong Jin Lee, Ju Seop Kang, Ok Hwa Jhee, Younghoon Kim, Shin-Hee Kim
Publikováno v:
Journal of Health Science. 57:378-383
Increased activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) has been implicated in the development of the metabolic syndromes by amplification of local glucocorticoid actions through regeneration of active glucocorticoid receptor. The
Publikováno v:
Journal of Health Science. 57:225-235
This study was made to investigate the anti-diabetic and antioxidant potential of ethanolic extract of seeds of Psoralea corylifolia L. in streptozotocin (STZ) nicotinamide induced type-2 diabetic rats. Male Albino Wistar rats (150-250 g) were taken
Autor:
Hiroomi Tamura, Tomomi Arao
Publikováno v:
Journal of Health Science. 57:436-441
Coffee is the beverage consumed during pregnancy that is most commonly associated with adversely affecting the developing fetoplacental unit. Since placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD-2) is an important determinant for mainte
Publikováno v:
Biological & Pharmaceutical Bulletin. 34:1619-1623
Microbial samples, including our library of known microbial compounds (ca. 300) and microbial culture broths (ca. 9000), were screened for small molecules affecting the phenotype of Caenorhabditis elegans. As a result, seven known compounds were foun
Publikováno v:
JOURNAL OF HEALTH SCIENCE. 57:397-400
The aromatic α,β-unsaturated carbonyl compounds are known to possess biological and pharmacological activities, such as antioxidative, antibacterial, and antiviral effects. We tested the affinities of six new compounds to bind to the catalytic site