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Cyproheptadine is first-generation antihistamine drug, that is, H1 receptor antagonist, with a drug being anesthetic, anti-serotonergic and anti-cholinergic and started to be used clinically in the 1960s. As firstly utilized as an anti-allergic drug,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905b0e4aa1b8eac2881f54fc83084c14
https://hdl.handle.net/20.500.12684/10471
https://hdl.handle.net/20.500.12684/10471
WOS: 000521117200001
PubMed: 31981560
In this study, we investigated the potential therapeutic effects of tofisopam, a 2,3-benzodiazepine derivative anxiolytic, on cognitive deficits in rats with scopolamine-induced amnesia. Cognitive perfo
PubMed: 31981560
In this study, we investigated the potential therapeutic effects of tofisopam, a 2,3-benzodiazepine derivative anxiolytic, on cognitive deficits in rats with scopolamine-induced amnesia. Cognitive perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68000fe3c34491514266989551a74735
https://hdl.handle.net/11421/23991
https://hdl.handle.net/11421/23991
Autor:
Laura Orio, R. Gómez de Heras, F. Rodríguez de Fonseca, José Antonio López-Moreno, C. Reyes-Cabello, I. Crespo
Publikováno v:
Pharmacology Biochemistry and Behavior; Vol 98
Cannabinoid CB1 receptor and cholecystokinin-1 (CCK 1 ) receptors are located in peripheral nerve terminals of the gut, where they mediate satiety signals. Here we describe a detailed analysis of the interaction of both receptors in the control of fe
Publikováno v:
Pharmacology Biochemistry and Behavior; Vol 97
The neurochemical basis of depression focuses on alterations in the monoaminergic and amino acid neurotransmitter systems. Moreover, decreases in serum levels of the neurotrophin brain-derived neurotrophic factor (BDNF) have led to the more recent ne
Autor:
Maria J. Falcão, Bruno P. Carreira, António F. Ambrósio, Caetana M. Carvalho, Inês M. Araújo, Maria Inês Morte, Patrício Soares-da-Silva
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
CIÊNCIAVITAE
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
CIÊNCIAVITAE
In this study we evaluated the neurotoxicity of eslicarbazepine acetate (ESL), and of its in vivo metabolites eslicarbazepine (S-Lic) and R-licarbazepine (R-Lic), as compared to the structurally-related compounds carbamazepine (CBZ) and oxcarbazepine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3791fda1ec215260da2c51b0e39525
https://hdl.handle.net/10400.1/11222
https://hdl.handle.net/10400.1/11222
Autor:
Mónica Muñoz-de-Toro, Enrique H. Luque, Verónica L. Bosquiazzo, Maria Mercedes Milesi, Jorgelina Varayoud
This study investigates the effects of neonatal exposure to low doses of endosulfan on the expression of proteins regulating uterine development and differentiation. Female pups received vehicle, endosulfan (Endo6: 6μg/kg, Endo600: 600μg/kg) or die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdeccf65074b8c98618c1129c6c910f6
Autor:
Sebastián García, Sebastián Casas, Federico Nanfaro, Ricardo Cabrera, Roberto Yunes, Carla Escudero
Hemiparkinsonisminduced by 6-hydroxydopamine (6-OHDA) injected in left corpus striatum is a recognized model of motor deficits in rats. Some reports concerning motor deficits indicate a favorable response to steroid administration in hemiparkinsonian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9b6a77ea16780081b987d1d4261249
https://www.sciencedirect.com/science/article/pii/S0091305711002048?via=ihub
https://www.sciencedirect.com/science/article/pii/S0091305711002048?via=ihub
Autor:
Mónica Muñoz-de-Toro, Horacio A. Rodríguez, Clarisa Guillermina Santamaria, Enrique H. Luque, Noelia Santambrosio
We evaluated whether exposure to bisphenol A (BPA) disrupts neonatal follicle development in rats. From postnatal day 1 (PND1) to PND7, pups received corn oil (control), diethylstilbestrol (DES20: 20 μg/kg-d, DES0.2: 0.2 μg/kg-d), or BPA (BPA20: 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f38a5eeeaee4b85f2625947ec49b59c
Autor:
J.L. Ulloa, P. Castañeda, Gabriela Díaz-Véliz, Jenny L. Fiedler, K. Araneda, C. Berrios, C. Menares, Javier A. Bravo, Paola Morales, Sergio Mora
Publikováno v:
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Depressive disorder involves emotional, cognitive, autonomic and endocrine alterations and also evidences support the role of stress in the development of this disorder. Because the hypothalamic-pituitary-adrenal axis is involved in the stress respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55af4bb91a7daef1ca668d855bc70085
Autor:
Talmir Augusto Faria Brizola dos Santos, Wilson Abrão Saad, Luiz Antonio de Arruda Camargo, William Abrão Saad, Ismael Francisco Motta Siqueira Guarda
Publikováno v:
Web of Science
Repositório Institucional da UNITAU
Universidade de Taubaté (UNITAU)
instacron:UNITAU
Repositório Institucional da UNITAU
Universidade de Taubaté (UNITAU)
instacron:UNITAU
Made available in DSpace on 2019-09-12T16:53:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2006 Calcium ions are widely accepted as critically important in responses of neurons to a stimulus. We have show previously the central involvement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1eafb1f4b0a3ad6a2c740b0cdc0d31
http://repositorio.unitau.br/jspui/handle/20.500.11874/2701
http://repositorio.unitau.br/jspui/handle/20.500.11874/2701