Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Manabu, Igarashi"'
Publikováno v:
PeerJ Physical Chemistry, Vol 3, p e19 (2021)
The substitution of Ile to Val at residue 117 (I117V) of neuraminidase (NA) reduces the susceptibility of the A/H5N1 influenza virus to oseltamivir (OTV). However, the molecular mechanism by which the I117V mutation affects the intermolecular interac
Externí odkaz:
https://doaj.org/article/2ec2189464f945cbaa831c4abf17bdf6
Publikováno v:
PeerJ, Vol 9, p e11552 (2021)
Background Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA reduces its binding affinity to OTV have not been
Externí odkaz:
https://doaj.org/article/2600a498d4e2469b943d215ca8de91f2
Publikováno v:
PeerJ Physical Chemistry, Vol 3, p e19 (2021)
The substitution of Ile to Val at residue 117 (I117V) of neuraminidase (NA) reduces the susceptibility of the A/H5N1 influenza virus to oseltamivir (OTV). However, the molecular mechanism by which the I117V mutation affects the intermolecular interac