Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yueh-Yun Chi"'
Autor:
Nathan Robison, Jasmine Pauly, Jemily Malvar, Sharon Gardner, Jeffrey Allen, Ashley Margol, Tobey MacDonald, Anne Bendel, Lindsay Kilburn, Andrew Cluster, Daniel Bowers, Kathleen Dorris, Nicole Ullrich, Rebecca Loret De Mola, Elizabeth Alva, Sarah Leary, Patricia Baxter, Ziad Khatib, Kenneth Cohen, Tom Belle Davidson, Ashley Plant, Pratiti Bandopadhayay, Sylwia Stopka, Nathalie Agar, Karen Wright, Marvin Nelson, Yueh-Yun Chi, Mark Kieran
Publikováno v:
Neuro-Oncology. 24:i191-i192
BACKGROUND RAS/RAF/MEK/ERK pathway activation is the primary driver for most pediatric low-grade gliomas (pLGG). MEK162 (binimetinib) is an orally bioavailable MEK1/2 inhibitor with superior brain penetration in a preclinical model. The primary objec
Publikováno v:
Neuro-Oncology. 24:i102-i102
BACKGROUND: MEK inhibition is an emerging treatment strategy in pediatric tumors characterized by activation of the Ras-Raf-MEK-ERK pathway, including low-grade glioma (LGG) and neurofibromatosis 1 (NF1)-associated tumors. Preliminary clinical experi
Autor:
Tammy Lo, Saumya D. Sisoudiya, Douglas R. Stewart, Yueh Yun Chi, Douglas S. Hawkins, Deborah Marquez-Do, Donna M. Muzny, Sharon E. Plon, Joshua D. Schiffman, Stephen X. Skapek, Richard A. Gibbs, Michael E. Scheurer, Shannon Dugan-Perez, Philip J. Lupo, Aniko Sabo, Donald A. Barkauskas, He Li, Eric Boerwinkle, Bailey Angeline Martin-Giacalone, David Hall, Michael M. Khayat
Publikováno v:
J Natl Cancer Inst
Background Several cancer-susceptibility syndromes are reported to underlie pediatric rhabdomyosarcoma (RMS); however, to our knowledge there have been no systematic efforts to characterize the heterogeneous genetic etiologies of this often-fatal mal
Autor:
Yueh Yun Chi, Xiao-Hua Zhou
Publikováno v:
Journal of the Royal Statistical Society Series C: Applied Statistics. 57:1-23
Summary In diagnostic medicine, the receiver operating characteristic (ROC) surface is one of the established tools for assessing the accuracy of a diagnostic test in discriminating three disease states, and the volume under the ROC surface has serve
Publikováno v:
Biometrika. 94:760-766
High-dimension, low-small-sample size datasets have different geometrical properties from those of traditional low-dimensional data. In their asymptotic study regarding increasing dimensionality with a fixed sample size, Hall et al. (2005) showed tha