Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan Tavernier"'
Autor:
T.M. Wijesuriya, Jan Tavernier, Rachel Wevrick, Leentje De Ceuninck, Karin Vanessa Carias, Delphine Masschaele, Matthea R. Sanderson
Publikováno v:
Human Molecular Genetics. 26:4215-4230
In Prader-Willi syndrome (PWS), obesity is caused by the disruption of appetite-controlling pathways in the brain. Two PWS candidate genes encode MAGEL2 and necdin, related melanoma antigen proteins that assemble into ubiquitination complexes. Mice l
Autor:
Sven Degroeve, Veronic De Puysseleyr, Irma Lemmens, Sam Lievens, Davy Maddelein, Surya Gupta, Jan Tavernier, José Van der Heyden, Lennart Martens
Publikováno v:
BIOINFORMATICS
Bioinformatics
Bioinformatics
Summary Protein-protein interaction (PPI) studies have dramatically expanded our knowledge about cellular behaviour and development in different conditions. A multitude of high-throughput PPI techniques have been developed to achieve proteome-scale c
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis
Autor:
Delphine Lavens, Frank Peelman, José Van der Heyden, Isabel Uyttendaele, Dominiek Catteeuw, Annick Verhee, Bertrand Van Schoubroeck, Julia Kurth, Sabine Hallenberger, Reginald Clayton, Jan Tavernier
Publikováno v:
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
NUCLEIC ACIDS RESEARCH
The host restriction factor Apobec3G is a cytidine deaminase that incorporates into HIV-1 virions and interferes with viral replication. The HIV-1 accessory protein Vif subverts Apobec3G by targeting it for proteasomal degradation. We propose a model
Publikováno v:
Journal of Leukocyte Biology. 57:813-819
A characteristic feature of chronic allergic diseases such as asthma is the increase in eosinophil numbers in the inflamed tissue. In light of its specificity for the development of eosinophils, interleukin-5 (IL-5) is considered the most important c
Publikováno v:
Protein engineering
The mechanism by which tumour necrosis factors (TNF and lymphotoxin, also called TNF alpha and TNF beta respectively) exert their cytotoxic activity on many malignant cells, remains largely unknown. Furthermore, the broad array of differentiation (ge
Publikováno v:
NUCLEIC ACIDS RESEARCH
Northern blot analysis reveals that total RNA from human fibroblastoid cells (MG 63) induced with poly(I).poly(C) under conditions of IFN-beta production, contains predominantly a +/- 1,200 nucleotide long poly (A) mRNA (mRNA.M) which hybridizes with