Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David G. Hoel"'
Publikováno v:
Clinical Chemistry. 55:165-169
Background: Laboratory studies often involve analyses of highly skewed data for which means are not an adequate measure of central tendency because they are sensitive to outliers. Attempts to transform skewed data to symmetry are not always successfu
Publikováno v:
American Journal of Epidemiology. 163:S93-S93
Autor:
Amanda R. Harmon, David G. Hoel, Daniel T. Lackland, Stuart R. Lipsitz, James D. Thomas, Brent M. Egan, Joyce S. Nicholas
Publikováno v:
American Journal of Hypertension. 17:S131
Autor:
David G. Hoel, Gerald R. Chase
Publikováno v:
Biometrika. 62:329-334
SUMMARY The effect of small errors of dilution is shown to be sizeable when serial dilutions are required to estimate particle concentrations. Optimal dilution designs are given. The error effect and optimal design are also investigated for ratios of
Publikováno v:
Biometrika. 62:195-200
We examine results produced by a new likelihood stopping rule for terminating clinical trials, designed to choose the better of two competing dichotomous treatments, or to decide that they are equal. A method for adaptive assignment is also discussed
Publikováno v:
Toxicological Sciences. 5:79-86
Autor:
Kenny S. Crump, David G. Hoel
Publikováno v:
Biometrika. 61:237-252
SUMMARY A number of mathematical models for cell populations in which mutations are occurring are studied and compared by viewing the models as filtered Poisson processes. Based upon these models, a statistical analysis is given of the mutant accumul
Autor:
Christopher J. Portier, David G. Hoel
Publikováno v:
Toxicological Sciences. 4:949-959
The effect of bioassay design changes on the variability of risk estimates in the experimental dose region is investigated. Three-dose designs with a control group and other "usual" designs utilizing 200 animals are studied in detail. Constraints on
Autor:
KENNETH G. BROWN, DAVID G. HOEL
Publikováno v:
Toxicological Sciences. 3:458-469
Autor:
David G. Hoel
Publikováno v:
Biometrika. 55:387-391
SUMMARY This paper is concerned with the application of several closed sequential procedures to the testing of an exponential parameter. In particular, the procedures of Armitage (1957), Schneiderman & Armitage (1962a,b) and Anderson (1960) are consi