Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Atsushi Kumanogoh"'
Autor:
Eri Itotagawa, Yoshihiko Tomofuji, Yasuhiro Kato, Hachiro Konaka, Kohei Tsujimoto, JeongHoon Park, Daiki Nagira, Takehiro Hirayama, Tatsunori Jo, Toru Hirano, Takayoshi Morita, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Yukinori Okada, Hyota Takamatsu, Atsushi Kumanogoh
Publikováno v:
Rheumatology. 62:1988-1997
Objective B-cell activating factor (BAFF) is implicated in SLE pathogenesis. Blocking BAFF signalling has contributed to reducing glucocorticoid dosage and preventing organ damage. However, clinical characteristics of patients who may benefit from th
Autor:
Akiko Kajihara, Takayoshi Morita, Yasuhiro Kato, Hachiro Konaka, Teruaki Murakami, Yuta Yamaguchi, Shohei Koyama, Hyota Takamatsu, Masayuki Nishide, Yuichi Maeda, Akane Watanabe, Sumiyuki Nishida, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh
Publikováno v:
International Immunology. 35:27-41
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease, and many peripheral immune cell populations (ICPs) are thought to be altered according to the course of the disease. However, it is unclear which ICPs are associated with the c
Autor:
Takehiro Hirayama, Takayoshi Morita, Kenji Funakoshi, Yuko Yoshimine, Saki Minoda, Teruaki Murakami, Yasutaka Okita, Masashi Narazaki, Atsushi Kumanogoh
Publikováno v:
Oxford Medical Case Reports. 2022
Takayasu arteritis (TAK) is a vasculitis that causes inflammation in the arterial walls of large blood vessels. The complication rate of pulmonary artery lesion in TAK has been reported to be relatively high. Severe pulmonary artery stenosis can caus
Autor:
Kyuto, Sonehara, Saori, Sakaue, Yuichi, Maeda, Jun, Hirata, Toshihiro, Kishikawa, Kenichi, Yamamoto, Hidetoshi, Matsuoka, Maiko, Yoshimura, Takuro, Nii, Shiro, Ohshima, Atsushi, Kumanogoh, Yukinori, Okada
Publikováno v:
Human Molecular Genetics. 31:1806-1820
Understanding the genetic effects on non-coding RNA (ncRNA) expression facilitates functional characterization of disease-associated genetic loci. Among several classes of ncRNAs, microRNAs (miRNAs) are key post-transcriptional gene regulators. Despi
Autor:
Yoshihito Shima, Akane Watanabe, Nobuto Inoue, Tetsuya Maruyama, Eiji Kunitomo, Kunihiko Hamano, Takashi Kawanishi, Masashi Takasugi, Atsushi Kumanogoh
Publikováno v:
Modern Rheumatology. 32:351-357
ObjectivesRaynaud’s phenomenon (RP) is a peripheral vascular disorder that frequently occurs in systemic sclerosis (SSc). Although therapeutic heating seems reasonable given that RP is elicited by cold stimuli, the effects of heating are still uncl
Publikováno v:
International Immunology
Semaphorins were originally identified as axon-guidance molecules essential for neural development. In addition to their functions in the neural system, members of the semaphorin family have critical functions in many pathophysiological processes, in
Autor:
Toshihiro Kishikawa, Hidetoshi Matsuoka, Yukihiko Saeki, Shigeyoshi Tsuji, Noriko Arase, Ken Suzuki, Jun Hirata, Shiro Ohshima, M. Yoshimura, Shinichiro Tsunoda, Kenichi Yamamoto, Masashi Narazaki, Yukinori Okada, Kiyoshi Takeda, Atsushi Kumanogoh, Tatsuo Masuda, Yuichi Maeda, Kotaro Ogawa, Takuro Nii, Masato Matsushita, Atsushi Ogata, Hidenori Inohara
Publikováno v:
International Immunology
Novel biomarkers of rheumatoid arthritis (RA), in addition to antibodies against cyclic citrullinated peptides, are required. Metabolome analysis is a promising approach to identify metabolite biomarkers for clinical diagnosis. We adopted a comprehen
Autor:
Wataru Ise, Shinya Tanaka, Tomohiro Kurosaki, Kentaro Fujii, Masashi Narazaki, Haruhiko Koseki, Atsushi Kumanogoh, Takanori Hasegawa
Publikováno v:
International Immunology. 32:683-690
Antibodies produced by plasma cells are critical for protection from infection. It has been demonstrated that global epigenetic modification, such as changes in DNA methylation, occurs during differentiation of plasma cells from B cells. However, the
Autor:
Sujin Kang, Atsushi Kumanogoh
Publikováno v:
International Immunology. 32:467-473
Macrophages are heterogeneous and plastic, and play several diverse functions in immune responses. Emerging data provide evidence of multiple roles for metabolic pathways in the control of macrophage effector functions. The diverse functions of macro
Publikováno v:
Rheumatology. 59:959-967
Objectives The therapeutic effects of IVIG in patients with ANCA-associated vasculitis (AAV) have not been established so far. This study aims to estimate the effects of IVIG on AAV by conducting a systematic review and meta-analysis. Methods A compr