Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Mohammad Faujul Kabir, Jazmyne L Jackson, Annie D Fuller, Leonny Gathuka, Adam L Karami, Don-Gerard Conde, Alena Klochkova, Anbin Mu, Kathy Q Cai, Andres J Klein-Szanto, Amanda B Muir, Kelly A Whelan
Publikováno v:
Carcinogenesis. 44:182-195
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of human malignancy, often displaying limited therapeutic response. Here, we examine the non-steroidal anti-inflammatory drug diclofenac (DCF) as a novel therapeutic agent
Autor:
Kathryn E. Hamilton, Koji Tanaka, Veronique Giroux, Hiroshi Nakagawa, Marie Pier Tetreault, Ju Seog Lee, Apple Long, Andres J. Klein-Szanto, Anil K. Rustgi, Kelly A. Whelan
Publikováno v:
Carcinogenesis. 36:598-606
Esophageal cells overexpressing epidermal growth factor receptor (EGFR) and TP53 mutation can invade into the extracellular matrix when grown in 3D-organotypic cultures (OTC) and mimic early invasion in esophageal squamous cell carcinoma (ESCC). We h
Publikováno v:
Carcinogenesis. 23:565-572
Proprotein convertases (PCs) have been implicated in tumor cell invasion by processing a variety of substrates including matrix metalloproteinases (MMPs). PACE4, a member of the family of PCs was shown to enhance mouse skin carcinoma progression by i
Publikováno v:
American Journal of Clinical Pathology. 102:695-698
Cyclin D1/PRAD 1, a cell cycle-related gene mapped to chromosome 11q13, has been found to be amplified in some breast cancers and squamous cell carcinomas of the head and neck, and esophagus. In this study, overexpression of cyclin D1/PRAD1 gene was
Publikováno v:
JNCI: Journal of the National Cancer Institute. 66:165-174
The ability of retinyl acetate to alter growth, differentiation, and synthesis of mucous glycoproteins in cell lines cloned from an adenocarcinoma (T-8) and a squamous cell carcinoma (1000 WT) was investigated with the use of F344 rats. Growth rate w
Autor:
Rafael Fridman, Andres J. Klein-Szanto, H. Ura, Curtis C. Harris, R. Daniel Bonfil, Reuven Reich, Roger R. Reddel
Publikováno v:
JNCI: Journal of the National Cancer Institute. 81:587-594
The in vivo growth behavior and invasive potential of normal and "immortalized" human bronchial epithelial cells were studied by xenotransplantation procedures, an in vitro assay of invasiveness, and determinations of type IV collagenase activity and
Publikováno v:
JNCI: Journal of the National Cancer Institute. 72:43-51
The localization of fluorescein-labeled lectins, i.e., concanavalin A (Con A), Ricinus communis-120 (RCA), and wheat-germ agglutinin (WGA), were studied histologically in F344 rat epithelial lesions produced in the course of chemical carcinogenesis.
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Inbred F344 rat tracheal transplants were exposed to 7,12-dimethylbenz(a)anthracene (DMBA) delivered at different release rates from intraluminal pellets made of various matrices to study the effect of carcinogen dose rate on the induction of lesions