Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alan P. Venook"'
Autor:
Sorbarikor Piawah, Kimmie Ng, Alan P. Venook, Federico Innocenti, Charles D. Blanke, Eileen M. O'Reilly, Marla Lipsyc-Sharf, Jeffrey A. Meyerhardt, Andrew B. Nixon, Katherine Van Loon, Tiffany M Bainter, Richard M. Goldberg, Chao Ma, Heinz-Josef Lenz, Robert J. Mayer, Sui Zhang, Fang-Shu Ou, Nadine Jackson McCleary, C. Fuchs, Donna Niedzwiecki, I-Wen Chang
Publikováno v:
J Natl Cancer Inst
BackgroundThe incidence of young-onset colorectal cancer (yoCRC) is increasing. It is unknown if there are survival differences between young and older patients with metastatic colorectal cancer (mCRC).MethodsWe studied the association of age with su
Autor:
Chia-Ching Jackie Wang, Stephanie Kim, Mary Feng, Andrew H. Ko, Matthew S. Susko, Chloe E. Atreya, Katherine Van Loon, Alan P. Venook, Mekhail Anwar, Angela Laffan, Ann A. Lazar
Publikováno v:
Oncologist
Background Anal squamous cell carcinoma (ASCC) is uncommon, yet seen more frequently in the setting of the human immunodeficiency virus (HIV). Chemoradiotherapy is the definitive modality of treatment for patients with ASCC; this study examines facto
Autor:
Robert J. Mayer, Emily Valentino, Alexander Zukiwski, Michele Ly, Allison F. O'Neill, David Markowitz, G. Leonard, Peter T. Kingham, Ghassan K. Abou-Alfa, Alan P. Venook, Cameron Brennan, Olca Basturk, Emir Hoti, James J. Harding, Adam C. Yopp, Michael P. LaQuaglia, John D. Gordan, Muhammad Shaalan Beg, Stephen Leong, Mikaela Bradley, Ken Ren, John Crown, Rachel Kobos
Publikováno v:
Oncologist
Lessons Learned The fibrolamellar carcinoma-associated DNAJB1-PRKACA gene fusion transcript RNA codes for the catalytic domain of protein kinase A and, thus, overexpression of Aurora kinase A. ENMD-2076 showed a favorable toxicity profile. The limite
Autor:
Robert J. Mayer, Donna Niedzwiecki, Sui Zhang, Alexander Hantel, Eric G. Wolfe, Shuji Ogino, Al B. Benson, Leonard B. Saltz, Daniel Atienza, Chao Ma, Michael J. Messino, Alan P. Venook, Rex B. Mowat, Hedy L. Kindler, Seohyuk Lee, Charles S. Fuchs, Cary P. Gross, Fang-Shu Ou, Melinda L. Irwin, Jeffrey A. Meyerhardt, Renaud Whittom
Publikováno v:
JNCI Cancer Spectrum
Background Disparities in colon cancer outcomes have been reported across race and socioeconomic status, which may reflect, in part, access to care. We sought to assess the influences of race and median household income (MHI) on outcomes among colon
Autor:
Heinz-Josef Lenz, Blase N. Polite, Donna Niedzwiecki, Crystal S. Denlinger, Justin C. Brown, Robert J. Mayer, Sui Zhang, Jeffrey A. Meyerhardt, Fang-Shu Ou, Bert H. O'Neil, Alan P. Venook, Kimmie Ng, Federico Innocenti, Eileen M. O'Reilly, Richard M. Goldberg, Charles D. Blanke, James N. Atkins, James E. Shaw, Charles S. Fuchs
Publikováno v:
JNCI Cancer Spectrum
Background Diabetes is a prognostic factor for some malignancies, but its association with outcome in patients with advanced or metastatic colorectal cancer (CRC) is less clear. Methods This cohort study was nested within a randomized trial of first-
Autor:
Chloe E. Atreya, Li Zhang, Mekhail Anwar, Alan P. Venook, Jeffrey R. Smith, Marissa B Savoie, Tami S. Rowen, E.L. Van Blarigan, Anna O. Levin, K. Van Loon, Angela Laffan, Stacey A. Kenfield, Alan Paciorek
Publikováno v:
The Journal of Sexual Medicine. 17:S221-S221
Autor:
Renaud Whittom, Justin C. Brown, Edward Giovannucci, Robert J. Mayer, Walter C. Willett, Leonard B. Saltz, Al B. Benson, Yanping Li, Xuehong Zhang, Sui Zhang, Alexander Hantel, Hedy L. Kindler, Daniel Atienza, Charles S. Fuchs, Donna Niedzwiecki, Kimmie Ng, Shuji Ogino, Michael J. Messino, Jeffrey A. Meyerhardt, Alan P. Venook, Rex B. Mowat
Publikováno v:
Jnci Cancer Spectrum
Background Energy balance–related risk factors for colon cancer recurrence and mortality—type II diabetes, hyperinsulinemia, inflammation, and visceral obesity—are positively correlated with consumption of refined grains and negatively correlat
Publikováno v:
The Oncologist. 15:42-52
Hepatocellular carcinoma (HCC) is a complex condition associated with a poor prognosis. Treatment outcomes are affected by multiple variables, including liver function, performance status of the patient, and tumor stage, making a multidisciplinary ap
Autor:
Bert H. O'Neil, Alan P. Venook
Publikováno v:
The Oncologist. 12:1425-1432
Hepatocellular carcinoma (HCC) is a disease that requires multidisciplinary management. There has been no widely accepted standard for systemic therapy for this disease until recently. This article briefly discusses the management of earlier stage HC
Autor:
Alan P. Venook
Publikováno v:
The Oncologist. 10:250-261
Learning Objectives After completing this course, the reader will be able to: Describe the evolution of cancer chemotherapy for patients with colorectal cancer.Discuss the current relevance of VEGF as a therapeutic target in colorectal cancer.Discuss