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pro vyhledávání: '"Aditi P. Singh"'
Autor:
Charu Aggarwal, Alisha P Maity, Joshua M Bauml, Qi Long, Tomas Aleman, Christine Ciunci, Christopher D’Avella, Melissa Volpe, Evan Anderson, Lisa Mc Cormick Jones, Lova Sun, Aditi P Singh, Melina E Marmarelis, Roger B Cohen, Corey J Langer, Ravi Amaravadi
Publikováno v:
The Oncologist.
Background In RAS-mutant tumors, combined MEK and autophagy inhibition using chloroquine demonstrated synthetic lethality in preclinical studies. This phase II trial evaluated the safety and activity of the MEK inhibitor binimetinib combined with hyd