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Autor:
Sacha Flammier, Sandrine Lemoine, Justine Bacchetta, Laurence Dubourg, Laurence Chardon, Manon Aurelle
Publikováno v:
Nephrology Dialysis Transplantation. 37:2150-2156
Background The assessment of phosphate homeostasis in clinical practice relies not only on circulating phosphate levels but also on phosphate tubular reabsorption, ideally assessed using the tubular maximum phosphate reabsorption per glomerular filtr
Publikováno v:
Nephrology Dialysis Transplantation. 38:819-825
Klotho is a transmembrane anti-ageing protein that exists in three forms, i.e. α-Klotho, β-Klotho and γ-Klotho, with distinct organ-specific expression and functions in the body. Here we focus on α-Klotho (hereafter Klotho), abundantly expressed
Autor:
Xiaomeng Chen, Dorry L. Segev, Jingyao Hong, Nadia M. Chu, Mara McAdams-DeMarco, Oksana Harasemiw, Indranil Dasgupta, Clara Bohm, Kevin J Fowler
Publikováno v:
Nephrol Dial Transplant
Background Cognitive impairment is common among persons with chronic kidney disease (CKD), due in part to reduced kidney function. Given that physical activity (PA) is known to mitigate cognitive decline, we examined whether associations between CKD
Autor:
Michał Nowicki, Bergur V. Stefánsson, C. David Sjöström, Fan Fan Hou, Dapa-Ckd Trial Committees, Niels Jongs, John J.V. McMurray, Peter Rossing, Ricardo Correa-Rotter, Glenn M. Chertow, Robert D. Toto, Investigators, David C. Wheeler, István Wittmann, Hiddo J.L. Heerspink, Anna Maria Langkilde, Tom Greene
Publikováno v:
Wheeler, D C, Jongs, N, Stefansson, B, Chertow, G M, Greene, T, Hou, F F, Langkilde, A M, McMurray, J J, Rossing, P, Nowicki, M, Wittmann, I, Correa-Rotter, R, Sjostrom, C D, Toto, R D, Heerspink, H J L & DAPA-CKD Trial Comm Investigators 2022, ' Safety and efficacy of dapagliflozin in patients with focal segmental glomerulosclerosis : a prespecified analysis of the dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial ', Nephrology Dialysis Transplantation, vol. 37, no. 9, pp. 1647–1656 . https://doi.org/10.1093/ndt/gfab335
Background Despite renin–angiotensin–aldosterone system blockade and immunosuppressive treatment, focal segmental glomerulosclerosis (FSGS) often progresses to kidney failure. The objective of this prespecified analysis of the dapagliflozin and p
Publikováno v:
Nephrology Dialysis Transplantation. 38:811-818
Spot determinations of the urine creatinine concentration are widely used as a substitute for 24-h urine collections. Expressed as the amount excreted per gram of creatinine, urine concentrations in a single-voided sample are often used to estimate 2
Autor:
Martin Tepel, Xin Chen, Angelika Szakallova, Berthold Hocher, Bernhard K. Krämer, Chang Chu, Ahmed A. Hasan
Publikováno v:
Nephrology Dialysis Transplantation. 37:1348-1356
Background Angiopoietin-2 (Ang-2) plays a pivotal role in pathological vascular remodeling and angiogenesis. Both vascular mechanisms are active in patients with end-stage renal disease (ESRD) and may contribute to the high mortality in these patient
Autor:
Anne Monique Nuyt, Anik Cloutier, Adrien Flahault, Thuy Mai Luu, Guillaume Bollée, Anne-Laure Lapeyraque, Robson A.S. Santos, Ramy El-Jalbout
Publikováno v:
Clinical Kidney Journal. 15:709-717
Background Plasma copeptin, a surrogate marker for vasopressin levels, is increased in neonates born preterm, particularly in those with a more severe neonatal course, as reflected by bronchopulmonary dysplasia. Copeptin levels in adulthood are unkno
Autor:
Praveen Thokala, James Fotheringham, Gill Rooney, Edith Poku, Susan Harnan, Marrissa Martyn-St James, Monica Hernández, Thilo Schaufler
Publikováno v:
Clinical Kidney Journal. 15:484-499
Background Chronic kidney disease–associated pruritus (CKD-aP) is a common and burdensome condition for end-stage kidney disease (ESKD) patients, especially those receiving haemodialysis. High-quality evidence of the relationship between CKD-aP and
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss S2, Pp S75-S84 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Autologous hematopoietic stem cell transplantation (ASCT) remains an important postremission treatment for acute leukemia (AL). It is known that some prognostic factors, such as age, cytogenetic and molecular risk stratification, and minimal residual
Autor:
Rachel E. Patzer, Jonathan E. Shaw, Jessica L Harding, Stephen P. McDonald, Jedidiah I. Morton, Dianna J Magliano
Publikováno v:
Nephrol Dial Transplant
Background The number of people with diabetes-related end-stage kidney disease (ESKD-DM) has doubled in the last two decades. We examined changes in excess mortality for people with ESKD-DM in the USA and Australia. Methods In this retrospective coho