Zobrazeno 1 - 10
of 98
pro vyhledávání: ''
Autor:
Xiaoli Luo, Pedro A. Jose, Caiyu Chen, Xue Gong, Cong Lan, Cheng Yu, Cuimei Hu, Chao Fan, Zaicheng Xu, Chunyu Zeng, Jialiang Wang, Hao Luo
Publikováno v:
Cardiovasc Res
Aims Exposure to maternal diabetes is associated with increased prevalence of hypertension in the offspring. The mechanisms underlying the prenatal programming of hypertension remain unclear. Because endoplasmic reticulum (ER) stress plays a key role
Autor:
Zhihao Liu, Guannan Meng, Xiaoxing Jin, Liping Zhou, Xiaoya Zhou, Lilei Yu, Hu Chen, Hong Jiang, Fuding Guo, Yanqiu Lai
Publikováno v:
Cardiovascular Research. 118:1821-1834
Aims The clinical use of antitumor agent doxorubicin (DOX) is hampered by its dose-dependent cardiotoxicity. Development of highly efficient and safe adjuvant intervention for preventing DOX-induced adverse cardiac events is urgently needed. We aimed
Autor:
Sisareuth Tan, Jean-Sébastien Silvestre, Kamaleswaran Keirththana, Alain Brisson, Thi Anh-Dao Tran, José Vilar, Philippe Menasché, Paul Alayrac, Thomas Hamada, Maria Franca Perotto, Nadia El Harane, Reem Al-Daccak, Dominique Charron, Laetitia Pidial, Valérie Bellamy, Nisa Renault, Hocine Rachid Hocine, Chloé Guillas, Manon Desgres, Ingrid Gomez, Bruna Lima Correa
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
AimsThe cardioprotective effects of human induced pluripotent stem cell-derived cardiovascular progenitor cells (CPC) are largely mediated by the paracrine release of extracellular vesicles (EV). We aimed to assess the immunological behaviour of EV-C
Autor:
Victoria C. Cogger, Jordi Gracia-Sancho, Carmen A. Peralta, Raquel Maeso-Díaz, Anabel Fernández-Iglesias, Alessandra Warren, Diana Hide, Jaime Bosch, David G. Le Couteur
Publikováno v:
Hide, Diana; Warren, Alessandra; Fernández-Iglesias, Anabel; Maeso-Díaz, Raquel; Peralta, Carmen; Le Couteur, David G; Bosch, Jaime; Cogger, Victoria C; Gracia-Sancho, Jordi (2020). Ischemia/reperfusion injury in the aged liver: The importance of the sinusoidal endothelium in developing therapeutic strategies for the elderly. The journals of gerontology. Series A, Biological sciences and medical sciences, 75(2), pp. 268-277. Oxford University Press 10.1093/gerona/glz012
The liver endothelium plays a key role in the progression and resolution of liver diseases in young and adult individuals. However, its role in older people remains unknown. We have herein evaluated the importance of the sinusoidal endothelium in the
Autor:
Koji Hashimoto, Alan C. Spector
Publikováno v:
Chemical Senses. 39:57-71
Although damage to gustatory cortex (GC) in the rat has been reported to severely impair, if not eliminate, retention of a presurgically conditioned taste aversion (CTA), it has equivocal effects on taste preference as measured by intake tests. Becau
Autor:
Jeremy P.T. Ward, Ievgen V. Strielkov, Igor V. Kizub, Silke Becker, Jesus Prieto-Lloret, Anatoly Soloviev, Yasin Shaifta, Philip I. Aaronson, Vladimir A. Snetkov
Publikováno v:
Kizub, I V, Strielkov, I V, Shaifta, Y, Becker, S, Prieto-Lloret, J, Snetkov, V A, Soloviev, A I, Aaronson, P I & Ward, J P T 2013, ' Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization ', Cardiovascular Research, vol. 99, no. 3, pp. 404-411 . https://doi.org/10.1093/cvr/cvt129
Cardiovascular Research
Cardiovascular Research
Aims: To determine the role of gap junctions (GJ) in hypoxic pulmonary vasoconstriction (HPV).Methods and results: Studies were performed in rat isolated intrapulmonary arteries (IPA) mounted on a myograph, and in anesthetized rats. Hypoxia induced a
Autor:
Hirokuni Arai, Shuki Mizutani, Susumu Muto, Akiko Itai, Akihito Sasaki, Go Haraguchi, Shozaburo Doi, Susumu Hosokawa, Mitsuaki Isobe
Publikováno v:
Cardiovascular Research. 99:35-43
Aims Proliferation of pulmonary arterial smooth muscle cells (PASMCs) is one histological sign of pulmonary arterial hypertension (PAH). We hypothesized that a signalling cascade from fibroblast growth factor 2 (FGF2) to plasminogen activator inhibit
Autor:
Anthie Ellis, Caryl E. Hill, Daniel J. Chaston, Hee-Sup Shin, Pernille B. Lærkegaard Hansen, Lauren Howitt, Ivana Y. Kuo
Publikováno v:
Howitt, L, Kuo, I Y, Ellis, A, Chaston, D J, Shin, H-S, Hansen, P B & Hill, C E 2013, ' Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles ', Advances in Cardiovascular Research, vol. 98, no. 3, pp. 449-457 . https://doi.org/10.1093/cvr/cvt043
Aims As cardiovascular disease is characterized by reduced nitric oxide bioavailability, our aim was to determine the impact of this change on the mechanism underlying vascular tone of pressurized arteries in vitro and in vivo . Methods and results W
Autor:
Roselyn White, Monir Ahmad, Bing S. Huang, Yannick Marc, Frans H. H. Leenen, Catherine Llorens-Cortes
Publikováno v:
Cardiovascular Research. 97:424-431
Aims In rats post-myocardial infarction (MI), activation of angiotensinergic pathways in the brain contributes to sympathetic hyperactivity and progressive left ventricle (LV) dysfunction. The present study examined whether angiotensin III (Ang III)
Autor:
Seock Won Youn, Yoo Wook Kwon, Hyun Jai Cho, Byung Hee Oh, Hae Young Lee, Sung Jin Kim, Hyo-Soo Kim, Sae Won Lee, Young Bae Park
Publikováno v:
Cardiovascular Research. 97:143-152
Aims Kruppel-like factor 2 (KLF2) is implicated as a key molecule maintaining endothelial function. This study was designed to evaluate the reciprocal regulation of KLF2 by the forkhead transcription factor FOXO1, and the 3-hydroxy-3-methylglutaryl c