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Publikováno v:
Nephrology Dialysis Transplantation. 38:819-825
Klotho is a transmembrane anti-ageing protein that exists in three forms, i.e. α-Klotho, β-Klotho and γ-Klotho, with distinct organ-specific expression and functions in the body. Here we focus on α-Klotho (hereafter Klotho), abundantly expressed
Autor:
Xiaomeng Chen, Dorry L. Segev, Jingyao Hong, Nadia M. Chu, Mara McAdams-DeMarco, Oksana Harasemiw, Indranil Dasgupta, Clara Bohm, Kevin J Fowler
Publikováno v:
Nephrol Dial Transplant
Background Cognitive impairment is common among persons with chronic kidney disease (CKD), due in part to reduced kidney function. Given that physical activity (PA) is known to mitigate cognitive decline, we examined whether associations between CKD
Autor:
Michał Nowicki, Bergur V. Stefánsson, C. David Sjöström, Fan Fan Hou, Dapa-Ckd Trial Committees, Niels Jongs, John J.V. McMurray, Peter Rossing, Ricardo Correa-Rotter, Glenn M. Chertow, Robert D. Toto, Investigators, David C. Wheeler, István Wittmann, Hiddo J.L. Heerspink, Anna Maria Langkilde, Tom Greene
Publikováno v:
Wheeler, D C, Jongs, N, Stefansson, B, Chertow, G M, Greene, T, Hou, F F, Langkilde, A M, McMurray, J J, Rossing, P, Nowicki, M, Wittmann, I, Correa-Rotter, R, Sjostrom, C D, Toto, R D, Heerspink, H J L & DAPA-CKD Trial Comm Investigators 2022, ' Safety and efficacy of dapagliflozin in patients with focal segmental glomerulosclerosis : a prespecified analysis of the dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial ', Nephrology Dialysis Transplantation, vol. 37, no. 9, pp. 1647–1656 . https://doi.org/10.1093/ndt/gfab335
Background Despite renin–angiotensin–aldosterone system blockade and immunosuppressive treatment, focal segmental glomerulosclerosis (FSGS) often progresses to kidney failure. The objective of this prespecified analysis of the dapagliflozin and p
Publikováno v:
Nephrology Dialysis Transplantation. 38:811-818
Spot determinations of the urine creatinine concentration are widely used as a substitute for 24-h urine collections. Expressed as the amount excreted per gram of creatinine, urine concentrations in a single-voided sample are often used to estimate 2
Autor:
Praveen Thokala, James Fotheringham, Gill Rooney, Edith Poku, Susan Harnan, Marrissa Martyn-St James, Monica Hernández, Thilo Schaufler
Publikováno v:
Clinical Kidney Journal. 15:484-499
Background Chronic kidney disease–associated pruritus (CKD-aP) is a common and burdensome condition for end-stage kidney disease (ESKD) patients, especially those receiving haemodialysis. High-quality evidence of the relationship between CKD-aP and
Autor:
Rachel E. Patzer, Jonathan E. Shaw, Jessica L Harding, Stephen P. McDonald, Jedidiah I. Morton, Dianna J Magliano
Publikováno v:
Nephrol Dial Transplant
Background The number of people with diabetes-related end-stage kidney disease (ESKD-DM) has doubled in the last two decades. We examined changes in excess mortality for people with ESKD-DM in the USA and Australia. Methods In this retrospective coho
Autor:
Kamyar Kalantar-Zadeh, Supriya Kumar, James A Sloand, Eric Wittbrodt, Glen James, Heleen van Haalen, Hungta Chen
Publikováno v:
Clinical Kidney Journal. 15:244-252
Background Long-term clinical outcome data from patients with non-dialysis-dependent (NDD) chronic kidney disease (CKD) are lacking. We characterized patients with NDD-CKD and anemia using real-world data from the USA. Methods This retrospective long
Autor:
Sara González-Pastor, Mercedes Lopez-Gonzalez, Esther Simarro-Rueda, Juan Alberto Piñero-Fernández, Andrea Domingo-Gallego, Laia Ejarque-Vila, Marc Pybus, Roser Torra, María Luisa Matoses-Ruipérez, Gema Ariceta, María Luisa Quintanilla-Mata, Leire Madariaga, Lluis Guirado, Elisabet Ars, Emilie Cornec-Le Gall
Publikováno v:
NEPHROLOGY DIALYSIS TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Background Proteinuria is a well-known risk factor for progressive kidney impairment. Recently, C-terminal cubilin (CUBN) variants have been associated with isolated proteinuria without progression of kidney disease. Methods Genetic testing of 347 fa
Publikováno v:
Nephrology Dialysis Transplantation. 38:291-299
Nephrologists may encounter many systemic problems in their patients, including involvement of the neurological system and the development of seizures. Seizures are defined as abnormal neurological functions that cause overstimulation of neurons in t
Autor:
Elisa Conde-Moreno, NATALIA CARRILLO-LOPEZ, Manuel A Fernandez-Rodriguez, Lara Valiño Rivas, Jordi Rovira, Maria jose Ramirez-bajo, Rafael Sanchez-Villanueva, Alberto Ortiz Arduan
Publikováno v:
Clinical Kidney Journal. 15:372-387
Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insuffici