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Autor:
Britt J. Andersen, Vanga K Marius, Olivier Kouadio Kouadio, Charles W. Goss, Gary J. Weil, Allassane Ouattara, Catherine M. Bjerum, Daphne Lew, Meite Aboulaye, Benjamin G. Koudou, Christopher L. King
Publikováno v:
Clinical Infectious Diseases. 74:2200-2208
Background Ivermectin (IVM) plus albendazole (ALB), or IA, is widely used in mass drug administration (MDA) programs that aim to eliminate lymphatic filariasis (LF) in Africa. However, IVM can cause severe adverse events in persons with heavy Loa loa
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1413-1416
Background Ivermectin is an antiparasitic drug being investigated in clinical trials for the prevention of COVID-19. However, there are concerns about the quality of some of these trials. Objectives To conduct a meta-analysis with randomized controll
Autor:
Dima Kabbani, Ashlesha Sonpar, Benson Weyant, Keith CK Lau, Mark Robbins, Sandra Campbell, Karen Doucette, Juan G. Abraldes, Tamara Loutfi, Marlene Chakhtoura, Elie Akl, Carlos Cervera
Publikováno v:
Open Forum Infectious Diseases. 10
Background Immune-based therapies are standard-of-care treatment for coronavirus disease 2019 (COVID-19) patients requiring hospitalization. However, safety concerns related to the potential risk of secondary infections may limit their use. Methods W
Autor:
Russell R. Kempker, Charles A. Peloquin, Henry M. Blumberg, Zaza Avaliani, Jeffrey M. Collins, Shorena Sabanadze, Maia Kipiani, Mariam Gujabidze, Tinatin Bakuradze, Alison Smith, Mohammad H. Al-Shaer, Teona Avaliani
Publikováno v:
Clin Infect Dis
Background The ability of antituberculosis drugs to cross the blood–brain barrier and reach the central nervous system is critical to their effectiveness in treating tuberculosis meningitis (TBM). We sought to fill a critical knowledge gap by provi
Autor:
Atefeh Bonyadi, Fariborz Mansour-Ghanaei, Farhang Babamahmoodi, Esmat Radmanesh, Hadiseh Hosamirudsari, Javad Khodadadi, Sara Sayar, Zeinab Mehrabi, Amir Reza Bahadori, Shahin Merat, Minoo Moghimi, Gholamali Eslami, Hashem Mousavi, Lotfollah Davoodi, Mona Ebrahimzadeh, Farahnaz Joukar, Amir Anushiravani, Ali Ali Asgari, Ali Reza Davoudi Badabi, Elham Barahimi, Saeed Jelvay, Zahra Poormontaseri, Aida Zeinali, Nasim Khajavirad, Minoosh Shabani, Hamideh Abbaspour Kasgari, Zohreh Azarkar, Rohollah Moslemi, Ahmad Hormati, Azadeh Ebrahimzadeh, Hani Esmaeilian, Shokrollah Salmanzadeh, Elham Akbarpour, Lili Rezaie Keikhaie, Kaitlyn McCann, Amir Mohammad Shabani, Abdolali Tousi, Mohammad Abdollahi, Sara Mobarak, Mohammadreza Naghipour, Hadi Mirzaei, Mohammadreza Salehi, Shervin Shokouhi, Bryony Simmons, Morteza Mobarak, Helia Nateghi Baygi, Jacob Levi, Mehdi Hassaniazad, Andrew Hill, Zahra Arizavi, Nasrollah Hasooni Bahrini, Seyed Ali Dehghan Manshadi, Fatemeh Dehghani, Hannah Wentzel, Hossein Pourmasoomi, Masoome Noori Jangi, Shoeleh Yaghoubi, Alireza Nateghi Baygi, Mehdi Salasi, Farnaz Zolfaghari, Sara Yeganeh, Elmira Azimi, Jalal Karimi, Hafez Fakheri, Mahdi Afshari, Tofigh Yaghubi Kalurazi, Anahita Sadeghi, Farshid Abedi, Sajedeh Mousaviasl, Zahra Nekoukar, Dorsa Merat, Masood Ziaee
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background: The combination of sofosbuvir (SOF) and daclatasvir (DCV) has shown preliminary efficacy for patients with COVID-19 in five open-label studies with small sample sizes. This larger trial aimed to assess if the addition of sofosbuvir and da
Autor:
Aaron MacCosham, François Coutlée, Ann N. Burchell, Eduardo L. Franco, Mariam El-Zein, Talía Malagón, Pierre-Paul Tellier
Publikováno v:
Clin Infect Dis
Background Infections with human papillomaviruses (HPVs) may enter a latent state, and eventually become reactivated following loss of immune control. It is unclear what proportion of incident HPV detections are reactivations of previous latent infec
Autor:
Ilaria Coledan, Rossella Gottardo, Lorenza Lambertenghi, Massimiliano Lanzafame, Silvia Gambino, Emanuela Lattuada, Stefano Nicolè, Sebastiano Rizzardo, Dora Luise, Sandro Vento
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:747-752
Background Short-cycle therapy (SCT) is the administration of ART for 4 or 5 consecutive days a week, followed by 3 or 2 days off therapy. Its benefits include improving patient satisfaction and reducing ART toxicity and costs. Methods In this observ
Autor:
Jennifer Yan, Susana Vaz Nery, Paul Arkell, Merita Monteiro, Daniel Bailey, Salvador Amaral, Sung Hye Kim, Johanna Wapling, Alberina do Carmo Vieira, Julia Angelina, Virginia da Conceicao, Jane E. Francis, Nicholas S S Fancourt's, Ian Marr, Alexander Matthews
Publikováno v:
Transactions of The Royal Society of Tropical Medicine and Hygiene. 116:531-537
Background Acute febrile illnesses (AFIs), including dengue, scrub typhus and leptospirosis, cause significant morbidity and mortality in Southeast Asia. Serological surveillance can be used to investigate the force and distribution of infections. Dr
Autor:
Luisa Galli, Daniel Blázquez-Gamero, Begoña Santiago-García, Robindra Basu Roy, Svetlana Velizarova, Ralph Schilling, Florian Götzinger, Elisabetta Venturini, Marc Tebruegge, Lola Falcón-Neyra, Maria Tsolia, Nuria Martinez-Alier, Cristina Lillo, Folke Brinkmann, Danilo Buonsenso, Steven B. Welch, Stephanie Thee, Renate Krüger, Antoni Noguera-Julian, Olaf Neth
Publikováno v:
Clinical Infectious Diseases. 75:372-381
[Background]: Currently, data on treatment, outcome, and prognostic factors in children with tuberculous meningitis (TBM) in Europe are limited. To date, most existing data on TBM originate from adult studies, or studies conducted in low-resource set
Autor:
Maureen B. Taylor, Emily M Panousis, Amna Faheem, Samira Mubareka, Elizabeth Bryce, Shiva Barati, Lily Yip, Patryk Aftanas, Andrew G Mc Arthur, Kuganya Nirmalarajah, Jeff Powis, Alainna J Jamal, Hamza Mbareche, Henna P Mistry, Kevin Katz, Allison J Mc Geer, Marc Veillette, Titus Wong, Simon Plenderleith, Natalie G Bell, Mohammad Mozafarihashjin, Robert A. Kozak, Jalees A. Nasir, Karren Prost, Angel X Li, Gloria Crowl, Saman Khan, Xi Zoe Zhong, Jonathon D Kotwa, Eric A. Coomes, Ryan J. Hiebert, Renee Schryer, Caroline Duchaine, Aimee Paterson, Lubna Farooqi
Publikováno v:
The Journal of Infectious Diseases. 225:768-776
Background We determined the burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in air and on surfaces in rooms of patients hospitalized with coronavirus disease 2019 (COVID-19) and investigated patient characteristics associated