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Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1413-1416
Background Ivermectin is an antiparasitic drug being investigated in clinical trials for the prevention of COVID-19. However, there are concerns about the quality of some of these trials. Objectives To conduct a meta-analysis with randomized controll
Autor:
Gagandeep Kang, Nathan Lo, Jacob John, Dilesh Kumar, Yanjia Cao, Theresa Ryckman, Arun S Karthikeyan, Jason R. Andrews, Jeremy D. Goldhaber-Fiebert
Publikováno v:
The Journal of Infectious Diseases. 224:S612-S624
Background Typhoid fever causes substantial global mortality, with almost half occurring in India. New typhoid vaccines are highly effective and recommended by the World Health Organization for high-burden settings. There is a need to determine wheth
Autor:
Venkata Raghava Mohan, Mathew Santosh Thomas, Madhu Gupta, Atul Sharma, Shankar Prinja, Christina Dhas Sankhro, Sulochana Putli Bai Perumal, Arti Kapil, Pallab Ray, Roshine Mary Koshy, Akashdeep Singh Chauhan, Reshma Raju, Arun S Karthikeyan, Gagandeep Kang, Saroj Kumar Rana, Shajin Thankaraj, Dasaratha Ramaiah Jinka, Karthikeyan Ramanujam, Savitha Nagaraj, Prasanna S. Premkumar, Swathi Krishna Njarekkattuvalappil, Karnika Saigal, Jayanthi Shastri, Sheena Evelyn Ebenezer, Shalini Anandan, Jacob John, Maria Thomas, Dilesh Kumar, Ashita Singh
Publikováno v:
The Journal of Infectious Diseases. 224:S540-S547
Background Lack of robust data on economic burden due to enteric fever in India has made decision making on typhoid vaccination a challenge. Surveillance for Enteric Fever network was established to address gaps in typhoid disease and economic burden
Autor:
Christian Eckmann, Paul M. Tulkens
Publikováno v:
Journal of Antimicrobial Chemotherapy
Bacterial skin and soft tissue infections are among the most common bacterial infections and constitute a major burden for patients and healthcare systems. Care is complicated by the variety of potential pathogens, some with resistance to previously
Autor:
Jonathan D. Crews, Matthew M Sattler
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:S27-S33
Children with Clostridioides difficile infection (CDI) can experience recurrent or severe disease. Recurrent CDI occurs in 20%-30% of children with an initial CDI episode. A careful clinical evaluation is important to distinguish recurrent CDI from o
Autor:
Matthew Dryden, Mark H. Wilcox
Publikováno v:
Journal of Antimicrobial Chemotherapy
Healthcare-associated infections (HCAIs) are a threat to patient safety and cause substantial medical and economic burden in acute care and long-term care facilities. Risk factors for HCAIs include patient characteristics, the type of care and the se
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:S16-S21
Although the pathogenesis of Clostridioides difficile infection (CDI) is complex and incompletely understood, it is believed that the elaboration of C. difficile toxins is necessary for disease. There are a variety of tests available for the detectio
Autor:
Jason C. Gallagher, Yngve Falck-Ytter, William J. Muller, Shmuel Shoham, Adarsh Bhimraj, John C. O’Horo, Lindsey R. Baden, Dana Swartzberg Wollins, Rajesh T. Gandhi, Amy Hirsch Shumaker, Vincent C.C. Cheng, Valery Lavergne, Kathryn M. Edwards, Rebecca L. Morgan
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Given the urgent need for treatments during the coronavirus disease 2019 pandemic, the US Food and Drug Administration issued emergency use authorizations (EUAs) for multiple therapies. In several instances, however, these EUAs were issued before suf
Autor:
Amy Hirsch Shumaker, Rajesh T. Gandhi, Kathryn M. Edwards, Vincent C.C. Cheng, Rebecca L. Morgan, Jason C. Gallagher, Lindsey R. Baden, William J. Muller, Adarsh Bhimraj, Dana Swartzberg Wollins, Yngve Falck-Ytter, John C. O’Horo, Shmuel Shoham
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Despite the challenges of the pandemic, there has been substantial progress with coronavirus disease 2019 (COVID-19) therapies. Pivotal COVID-19 trials like SOLIDARITY, RECOVERY, and ACCT-1 were rapidly conducted and data disseminated to support effe
Autor:
Michael Price, Hung S. Luu, Jennifer Fuchs, Michael E. Sebert, Ami Waters, Erin McElvania, Laura M. Filkins, Michelle S. Hsiang, Leigh Anna Stubbs, Daniel K. Noland
Publikováno v:
Journal of the Pediatric Infectious Diseases Society
In non-endemic settings, transfusion-transmitted malaria (TTM) is rare but potentially fatal and becoming more common with globalization. We present two pediatric cases that demonstrate donor screening using questionnaires is subject to error and tha