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Publikováno v:
Journal of Antimicrobial Chemotherapy
The long-acting antiretroviral cabotegravir and rilpivirine combination has just received FDA, EMA and Health Canada approval. This novel drug delivery approach is about to revolutionize the therapy of people living with HIV, decreasing the 365 daily
Publikováno v:
J Antimicrob Chemother
In 2020, new vancomycin guidelines were released, recommending the transition from trough-based to AUC24 monitoring for adult and paediatric patients. Given the resources required to achieve this transition, there has been debate about the costs and
Autor:
Anne-Sophie Lemaire-Hurtel, Touria Mernissi, Loay Kontar, Sandra Bodeau, Aurélien Mary, Camille André, Youssef Bennis, Noël Zahr, Hervé Dupont
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:1643-1646
Autor:
Jing Zhang, Jiuhong Wu, Suodi Zhai, Rongsheng Zhao, Yingchun Xu, Aidong Wen, Xianglin Zhang, Gaolin Liu, Na He, Zhiping Li, Rongsheng Tong, Wei Zhao, Zhigang Chen, Li Wang, Shan Su, Kehu Yang, Xin Hu, Wenting Zhang, Wei Zhou, Xiao Chen, Huizhi Zhang, Guanhua Du, Yang Yang, Daihong Guo, Ruichen Guo, Yalin Dong, Siyan Zhan, Yaolong Chen, Wei Lu, Xin'an Wu, Zhigang Zhao, Minggui Wang, Bikui Zhang, Bei He, Rui Wang, Fan Yang, Jieming Qu, Guang Du, Limei Zhao, Jie Zhang, Youning Liu, Jun Zhang, Zhikang Ye, Dakui Li, Yuan Lv, Huande Li, Xian-Tao Zeng, Chao Zhang, Libo Zhao, Zheng Jiao, Jian Gu, Liyan Miao, Tieying Sun, Yingyuan Zhang
Publikováno v:
Clinical Infectious Diseases. 71:S363-S371
BackgroundClinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off. The scientific process of developing and updating guidelines accompanied b
Publikováno v:
Clinical Infectious Diseases. 72:e675-e681
Vancomycin is commonly prescribed to hospitalized patients. Decades of pharmacokinetic/pharmacodynamic research culminated in recommendations to monitor the ratio of the area under the concentration-time curve (AUC) to the minimum inhibitory concentr
Autor:
Nathaniel J. Rhodes, Michael Neely, Sean N. Avedissian, Nicolás Cortés-Penfield, Michael J. Rybak, John S. Bradley, Jennifer Le
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:2486-2488
Publikováno v:
Med Mycol
Pneumocystis jirovecii can cause life-threatening pneumonia in immunocompromised patients. Traditional diagnostic testing has relied on staining and direct visualization of the life-forms in bronchoalveolar lavage fluid. This method has proven insens
Publikováno v:
Open Forum Infectious Diseases
Background For the management of serious S. aureus infections, area-under-the curve to minimum inhibitory concentration (AUC/MIC) applied dosing is recommended as the preferred method to goal trough-based monitoring. This pharmacodynamic dosing demon
Publikováno v:
Oxford Medical Case Reports
An unresponsive paediatric patient may present a diagnostic challenge for health professionals, as rapid identification of the cause is needed to provide proper interventions. The following report details a challenging diagnosis of unresponsiveness i
Publikováno v:
Journal of Tropical Pediatrics. 64:426-433
Background Malaria and acute bacterial meningitis (ABM) are the leading infectious causes of febrile encephalopathy in malaria endemic settings. The clinical distinction of the two conditions is complicated by overlap in clinical features. Objective