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Autor:
Jose Marquez, Zayd Al Rawi, Elizabeth C. Bryda, Daniel J. Davis, Mona O. Garro-Kacher, Caley E. Smith, Christian L. Lorson, Catherine L Smith, Nicole L. Nichols, Amy N Keilholz, Jiude Mao, Eric Villalón, Sara M. Ricardez Hernandez, Toni I. Morcos, Monique A. Lorson
Publikováno v:
Hum Mol Genet
Spinal muscular atrophy with respiratory distress type I (SMARD1) is a neurodegenerative disease defined by respiratory distress, muscle atrophy and sensory and autonomic nervous system defects. SMARD1 is a result of mutations within the IGHMBP2 gene
Autor:
Claudia F. Lucchinetti, Sean J. Pittock, Yong Guo, Vanda A. Lennon, Charles L. Howe, Joseph E. Parisi, Christina Vasquez, Bogdan F. Gh. Popescu
Publikováno v:
Brain. 145:1379-1390
Neuromyelitis optica is an autoimmune inflammatory disorder targeting aquaporin-4 water channels in CNS astrocytes. Histopathological descriptions of astrocytic lesions reported in neuromyelitis optica so far have emphasized a characteristic loss of
Autor:
Toshiyuki Kakumoto, Meiko Hashimoto Maeda, Akatsuki Kubota, Keishi Fujio, Masanori Kono, Hayato Yuki, Toshihiko Komai, Tatsushi Toda, Norio Hanata, Hirofumi Shoda
Publikováno v:
Modern Rheumatology Case Reports. 6:64-68
Idiopathic inflammatory myopathies (IIMs) are autoimmune diseases predominantly affecting proximal muscles; paraspinal muscle involvement is relatively rare. Because paraspinal myopathies do not always cause clinically evident symptoms, the diagnosis
Autor:
Kristian Nygaard Mortensen, Genaro Olveda, Hajime Hirase, Benjamin T. Kress, Douglas H. Kelley, Guojun Liu, John H. Thomas, Edna R Toro, Amanda M. Sweeney, Poul G. Hjorth, Weiguo Peng, Andrew J. Samson, Erik A. Martens, Rupal I Mehta, Peter A. R. Bork, Yuki Mori, Jeffrey Tithof, Logan Bashford, Ting Du, Humberto Mestre, Martin Kaag Rasmussen
Publikováno v:
Du, T, Mestre, H, Kress, B T, Liu, G, Sweeney, A M, Samson, A J, Rasmussen, M K, Mortensen, K N, Bork, P A R, Peng, W, Olveda, G E, Bashford, L, Toro, E R, Tithof, J, Kelley, D H, Thomas, J H, Hjorth, P G, Martens, E A, Mehta, R I, Hirase, H, Mori, Y & Nedergaard, M 2022, ' Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema ', Brain, vol. 145, no. 2, pp. 787–797 . https://doi.org/10.1093/brain/awab293
Brain
Brain
Cerebral oedema develops after anoxic brain injury. In two models of asphyxial and asystolic cardiac arrest without resuscitation, we found that oedema develops shortly after anoxia secondary to terminal depolarizations and the abnormal entry of CSF.
Autor:
John W. Prineas, John Parratt
Publikováno v:
Journal of Neuropathology and Experimental Neurology
This study examined the roles of microglia and monocytes in myelin destruction in patients with early multiple sclerosis (MS). Twenty-two cases were studied; the clinical duration was
Autor:
Soraya Mezouar, Sophie Collardeau-Frachon, Laurent Daniel, Florence Bretelle, Delphine Sirgant, Julia Torrents, Emmanuelle Lesieur, Hubert Lepidi, Christine Zandotti, Radia Fritih, Frédéric Fina, Jean-Louis Mege, Myriem Otmani Idrissi, Celine Gazin, Julie Blanc
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases, 2022, 75 (1), pp.E1092-E1100. ⟨10.1093/cid/ciab840⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 2022, 75 (1), pp.E1092-E1100. ⟨10.1093/cid/ciab840⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Observations of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from mother to fetus have recently been described in the literature. However, the consequences of such transmission, whether fe
Publikováno v:
American Journal of Clinical Pathology. 157:202-211
Objectives In this retrospective study, we report a series of benign lymph nodes showing small populations of normal B-cell precursors characterized by flow cytometry and immunohistochemistry. Methods Ten cases identified during clinical flow cytomet
Autor:
Yan Zhao, Jasper Fuk-Woo Chan, Kelvin K. W. To, Can Li, Yanxia Chen, Wan-Man Wong, Ivan Hung, Fei-Fei Liu, David Christopher Lung, Kin-Hang Kok, Wenchen Song, Dong-Yan Jin, Kwok-Yung Yuen, Zhanhong Ye, Hin Chu, Anna Jinxia Zhang, Jian-Piao Cai, Siddharth Sridhar, Cyril C. Y. Yip
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Post-vaccination myopericarditis is reported after immunization with coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccines. The effect of inadvertent intravenous injection of this vaccine on the heart is unknown. Methods We com
Autor:
Moe R Takeda, Maria E. Vergara-Lluri
Publikováno v:
The Journal of Applied Laboratory Medicine. 6:1677-1682
Publikováno v:
Rheumatology. 61:1690-1698
Objectives To investigate whether physical activity interferes with joint homeostasis in the presence of distant inflammation originating at barrier tissues such as skin or gut. Methods Eight-week-old male C57/Bl6 mice were treated with imiquimod cre