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Autor:
Sara González-Pastor, Mercedes Lopez-Gonzalez, Esther Simarro-Rueda, Juan Alberto Piñero-Fernández, Andrea Domingo-Gallego, Laia Ejarque-Vila, Marc Pybus, Roser Torra, María Luisa Matoses-Ruipérez, Gema Ariceta, María Luisa Quintanilla-Mata, Leire Madariaga, Lluis Guirado, Elisabet Ars, Emilie Cornec-Le Gall
Publikováno v:
NEPHROLOGY DIALYSIS TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Background Proteinuria is a well-known risk factor for progressive kidney impairment. Recently, C-terminal cubilin (CUBN) variants have been associated with isolated proteinuria without progression of kidney disease. Methods Genetic testing of 347 fa
Autor:
Mohan Rajapurkar, Arpita Ghosh, Vivekanand Jha, Vivek Kumar, Banibrata Mukhopadhyay, Smita Divyaveer, Monica Kundu, Suhas S. Lele, Ashok Kumar Yadav
Publikováno v:
Nephrology Dialysis Transplantation. 37:1879-1887
Background The non-transferrin-bound catalytic iron moiety catalyses production of toxic reactive oxygen species and is associated with adverse outcomes. We hypothesized that serum catalytic iron (SCI) is associated with progression of chronic kidney
Autor:
Yuki Oba, Hirofumi Makino, Daisuke Ikuma, Norihiko Sakai, Miho Shimizu, Tatsuya Suwabe, Takashi Wada, Masayuki Yamanouchi, Yukio Yuzawa, Ken-ichi Samejima, Seiichi Matsuo, Megumi Oshima, Yuta Yamamura, Shinichi Nishi, Tomoya Nishino, Shusaku Matsuoka, Tadashi Toyama, Yoshihiko Ueda, Yoshiki Suzuki, Hiroki Mizuno, Akinori Hara, Yugo Shibagaki, Hiroshi Kitamura, Shinji Kitajima, Yasunori Iwata, Junichi Hoshino, Hiroshi Sato, Noriko Uesugi, Naoki Sawa, Hitoshi Yokoyama, Kentaro Kohagura, Yoshifumi Ubara, Kengo Furuichi
Publikováno v:
Nephrology Dialysis Transplantation. 37:489-497
Background Prognosticating disease progression in patients with diabetic kidney disease (DKD) is challenging, especially in the early stages of kidney disease. Anemia can occur in the early stages of kidney disease in diabetes. We therefore postulate
Autor:
Esteban Porrini, Justo Sandino, Lucia Aubert, Florencio García-Martín, Julian Segura, Elena Gutierrez-Solis, Enrique Morales
Publikováno v:
Nephrology Dialysis Transplantation. 37:1125-1131
Background The increasing prevalence of type 2 diabetes mellitus (T2DM) has influenced in an increasing prevalence of chronic kidney disease (CKD). Little is known about the influence of non-alcoholic fatty liver disease (NAFLD) on the progression of
Autor:
Ciro Esposito, Avtandil Tataradze, Udaya Valluri, Władysław Sułowicz, Michael Reusch, Evgeny Shutov, Nada Dimkovic, Branislav Andric
Publikováno v:
Nephrology Dialysis Transplantation
Background Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of chronic kidney disease (CKD) anemia. Methods This Phase 3, multicenter, randomized, double-blind, placebo-controlled study examined p
Autor:
Francis Verbeke, Eva Schepers, Raymond Vanholder, Anneleen Pletinck, Marijn M. Speeckaert, Nathalie Neirynck, Dirk De Bacquer, Wim Van Biesen, Griet Glorieux
Publikováno v:
Nephrology Dialysis Transplantation. 36:998-1005
Background Several protein-bound uraemic toxins (PBUTs) have been associated with cardiovascular (CV) and all-cause mortality in chronic kidney disease (CKD) but the degree to which this is the case per individual PBUT and the pathophysiological mech
Publikováno v:
Clinical Kidney Journal
Vrije Universiteit Brussel
Vrije Universiteit Brussel
Background The disease course of adult immunoglobulin A (IgA) vasculitis (IgAV; Henoch–Schönlein purpura) has not been well defined. Methods In a retrospective survey, we studied 85 adult IgAV patients with extended follow-up (median 43 months) fo
Autor:
Alejandro Best Rocha, Anthony M. Valeri, Christopher P. Larsen, Mohamad Sandid, Mary E. Fidler, Samar M. Said, Mariam P. Alexander, Samih H. Nasr, Anhisekh Sinha Ray
Publikováno v:
Clinical Kidney Journal
Background Coexistence of fibrillary glomerulonephritis (FGN) and immunoglobulin A (IgA) nephropathy (IgAN) in the same kidney biopsy (FGN–IgAN) is rare, and the clinicopathologic characteristics and outcome of this dual glomerulopathy are unknown.
Autor:
Jing Chen, Matthew R. Weir, Dominic S. Raj, Anand Srivastava, Sophia Zhao, Sagar U. Nigwekar, Anne Frydrych, Tariq Shafi, Andrew S. Allegretti, Rajat Deo, James H. Sondheimer, James P. Lash, Ravi Thadhani, Anders H. Berg, Subbian Ananth Karumanchi, Cric Study Investigators, Sahir Kalim
Publikováno v:
Nephrology Dialysis Transplantation. 37:139-147
Background Protein carbamylation is a post-translational protein modification caused, in part, by exposure to urea’s dissociation product cyanate. Carbamylation is linked to cardiovascular outcomes and mortality in dialysis-dependent end-stage kidn
Autor:
Marie Essig, Guy Touchard, Eve Vilaine, Aymeric Couturier, Elyanne Gault, Ziad A. Massy, Sihem Kaaki, Jean-Michel Goujon, Mathilde Dargelos, A.-M. Roque-Afonso, Sophie Ferlicot, Cecile Ory
Publikováno v:
Clinical Kidney Journal
Background The objectives were to characterize Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease 2019 (COVID-19) in patients with acute kidney injury (AKI). Methods Kidney biopsy samples in two Caucasian patients and one African wi