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Autor:
Hugo Navarrete, Manuel Echeverría, Camilo Zurita, Gabriela Sevillano, Ariane Paz y Miño, Vicente Peñaherrera, Jeannete Zurita
Publikováno v:
Journal of Applied Microbiology. 132:2694-2704
Aims We described the presence of Helicobacter pylori (HP) and estimated the prevalence of primary and secondary resistance using molecular detection in gastric biopsies of Ecuadorian patients. Methods and Results 66.7% (238/357) of the patients demo
Autor:
Takashi Akamizu, Mako Hisakado, Takumi Kudo, Mitsushige Nishikawa, Shuji Fukata, Akira Miyauchi, Eijun Nishihara, Mikiko Okazaki-Hada, Mitsuru Ito
Publikováno v:
European Journal of Endocrinology. 186:73-82
Objective Resistance to thyroid hormone beta (RTHβ) is an inherited syndrome caused by mutations in the thyroid hormone receptor β (THRB) gene. Patients with RTHβ typically have elevated thyroid hormone levels with non-suppressed serum thyroid-sti
Publikováno v:
European Journal of Endocrinology. 185:819-829
Background Obesity is associated with impaired immune function and chronic low-grade inflammation. Metabolic surgery is one of the most effective therapies for treating obesity and related metabolic disorders. We aimed to explore the pathophysiologic
Autor:
Nadezda Machkova, Martin Lukas, Kristyna Kastylova, D. Duricova, Marta Kostrejová, Katarina Mitrova, Vladimír Teplan, Milan Lukáš, Martin Vašátko, Kristyna Kubickova, Veronika Hruba, Karin Cerna
Publikováno v:
Inflammatory Bowel Diseases. 28:1506-1512
Background Patients with inflammatory bowel disease (IBD) on immune-modifying treatment could be at an increased risk for severe coronavirus disease 2019 (COVID-19); thus, data on the efficacy and safety of severe acute respiratory syndrome coronavir
Autor:
Jacqueline McBride, Bartosz Korczowksi, K T Park, Gaohong She, Astrid Scalori, Regan Li, Jaroslaw Kierkus, Franklin Fuh, AK Kadva, Mariam Abouhossein, Meina Tao Tang, Wenhui Zhang
Publikováno v:
Inflammatory Bowel Diseases. 28:1348-1356
Background Etrolizumab, a humanized anti-β7 antibody, has not been studied in children. Here, we evaluate the pharmacokinetics, pharmacodynamics, and safety of etrolizumab in children with inflammatory bowel disease. Methods Patients age 4 to 17 yea
Autor:
Russell R. Kempker, Charles A. Peloquin, Henry M. Blumberg, Zaza Avaliani, Jeffrey M. Collins, Shorena Sabanadze, Maia Kipiani, Mariam Gujabidze, Tinatin Bakuradze, Alison Smith, Mohammad H. Al-Shaer, Teona Avaliani
Publikováno v:
Clin Infect Dis
Background The ability of antituberculosis drugs to cross the blood–brain barrier and reach the central nervous system is critical to their effectiveness in treating tuberculosis meningitis (TBM). We sought to fill a critical knowledge gap by provi
Autor:
M. Larue, T. Comont, Arsène Mekinian, L. Terriou, T. Cluzeau, Y. Jamilloux, M. Roux-Sauvat, Benjamin Terrier, J. Graveleau, J. Vinit, M. Gerfaud-Valentin, C. Arnaud, P. Biscay, H. Lobbes, Marie Sebert, A.F. Guedon, P. Henneton, P. Sujobert, M. Ebbo, V. Jachiet, T. Moulinet, F. Carrat, Jean-David Bouaziz, S. Ardois, A. Aouba, François Chasset, M. Heiblig, J. Rossignol, B. Faucher, Lionel Ades, E. Lazaro, E. Duroyon, N. Magy-Bertrand, A. Meyer, G. Vial, G. Boursier, B. Bienvenu, T. Hanslik, L. Sailler, Claude Bachmeyer, S. Audia, Pierre Fenaux, M. Samson, E. Flamarion, A. Audemard-Verger, B. de Sainte Marie, L.P. Zhao, E. Liozon, R. Outh, T. Weitten, R. Bourguiba, O. Kosmider, Sophie Georgin-Lavialle, J. Jeannel, G. Le Guenno, P. Hirsch, V. Lacombe, A. Mathian, S. Humbert, J. Galland, V. Guillotin, C. Deligny, Laurence Bouillet, M. Kostine, C. Dieval, P. Marianetti, A. Servettaz, B. Henriot, F. Borlot, O. Fain, A. Bigot, G. Sarrabay, S. Vinzio
Publikováno v:
British Journal of Dermatology. 186:564-574
A new autoinflammatory syndrome related to somatic mutations of UBA1 was recently described and called VEXAS syndrome ('Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic syndrome').To describe clinical characteristics, laboratory findings and
Publikováno v:
Modern Rheumatology Case Reports. 6:189-193
Dermatomyositis (DM) is an inflammatory myopathy (IIM) characterized by proximal muscle weakness and pathognomonic skin lesions. A 69-year-old woman with a recent diagnosis of DM 1 month prior, treated with corticosteroids and immunomodulators, prese
Autor:
R K Shandil, Nathella Pavankumar, Hemanth Kumar, Devaraju Reddy, Anant Mohan, Jaykumar Menon, L Sekar, Chandrasekaran Padmapriydarsini, Metrif Team, P. Ramesh, Megha Mamulwar, Randeep Guleria, N S Gomathy, Prema Shanmugam, Shaheed M Jawahar, Chandra Suresh, Poornaganga Devi, Abhijeet Kadam, Manjula Singh, Urvashi B. Singh, Aarti Mane
Publikováno v:
Clinical Infectious Diseases. 75:425-434
Background Metformin, by reducing intracellular Mycobacterium tuberculosis growth, can be considered an adjunctive therapy to anti-tuberculosis treatment (ATT). We determined whether metformin with standard ATT reduces time to sputum culture conversi
Publikováno v:
Modern Rheumatology. 32:1035-1040
Objectives Indeed, serum amyloid A (SAA) and C-reactive protein (CRP) reportedly seem to have moderate correlation, but discrepancies between CRP and SAA levels have often been reported in patients with early rheumatoid arthritis (ERA). This study ai