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Autor:
Rachel L. Byrne, Derek Cocker, Ghaith Alyayyoussi, M. Mphasa, Mary Charles, Tamandani Mandula, Christopher T. Williams, Jonathan Rigby, Jack Hearn, Nicholas Feasey, Emily R. Adams, Thomas Edwards
Publikováno v:
Journal of Applied Microbiology. 133:3191-3200
BackgroundEnvironmental water samples are increasingly recognised as an important reservoir of antimicrobial resistance (AMR) genes. Polymerase chain reaction (PCR) and next generation sequencing (NGS) offer a potentially inclusive surveillance platf
Autor:
Christian Eckmann, Paul M. Tulkens
Publikováno v:
Journal of Antimicrobial Chemotherapy
Bacterial skin and soft tissue infections are among the most common bacterial infections and constitute a major burden for patients and healthcare systems. Care is complicated by the variety of potential pathogens, some with resistance to previously
Publikováno v:
J Antimicrob Chemother
Background The cyclic anionic lipopeptide daptomycin is used in the treatment of severe infections caused by Gram-positive pathogens, including MRSA. Daptomycin resistance, although rare, often results in treatment failure. Paradoxically, in MRSA, da
Publikováno v:
Journal of AOAC INTERNATIONAL. 105:346-351
Background Ochratoxin A (OTA) is a harmful mycotoxin and secondary metabolite produced by several species of Aspergillus and Penicillium. It is of vital importance to establish a sensitive method to detect OTA in various grains. Objective A novel, hi
Autor:
Michael Constantine, Romualdo Barroso-Sousa, Tianyu Li, Eric P. Winer, Meredith Faggen, Antonio Di Meglio, Nabihah Tayob, Harold J. Burstein, Caroline Block, Natalie Faye Sinclair, Rebecca Rees, Nan Lin, Ann H. Partridge, Ines Vaz-Luis, Sara M. Tolaney, Jiani Hu, Michael J. Hassett, Jose Pablo Leone, Lindsey Milisits, Frederick Briccetti, Lorenzo Trippa, Adrienne G. Waks
Publikováno v:
The Oncologist
Background In early trials, hypersensitivity reactions (HSRs) to paclitaxel were common, thus prompting the administration of antihistamines and corticosteroids before every paclitaxel dose. We tested the safety of omitting corticosteroids after cycl
Autor:
Teresa R Gray, Crystal Arndt
Publikováno v:
Journal of Analytical Toxicology. 46:e73-e77
Phenibut, a GABAB agonist structurally similar to baclofen, is not approved for medical use in the USA but is available through internet suppliers for recreational use. Calls to poison control centers for phenibut have increased over the last 5 years
Publikováno v:
Letters in Applied Microbiology. 73:544-552
Biofilms are oft cited as a factor in the unwanted persistence and recalcitrance of microbial life and a strong research initiative exists to identify, understand, and target vulnerabilities. Phytoglycogen is a biodegradable nanoparticulate biomateri
Publikováno v:
Toxicological Sciences. 183:363-377
Aflatoxin B1 (AFB1) induced intestinal epithelial damage in rodent models, which indicates that long-term exposure to AFB1 may cause chronic gut disorders. In this study, we tested the hypothesis that AFB1-induced adverse effects on gut is mediated b
Autor:
Yan Guo, Bo Zheng, Ziyong Sun, Yunsong Yu, Ying Zhu, Zhongju Chen, Yingchun Xu, Ge Zhang, Wei Kang, Jingjia Zhang, Peiyao Jia, Jie Lin, Simeng Duan, Haixia Li, Qiwen Yang, Tong Wang, Xue Li, Yuan Lv, Ran Jing, Yun Li, Fupin Hu, Minggui Wang
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:2593-2599
Objectives To establish the epidemiological cut-off values (ECOFFs) for cefoselis against Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis and Pseudomonas aeruginosa. Methods We collected 2288 non-repetitive clinical i
Autor:
Supanat Burinkul, Punkavee Tuntiviriyapun, Ammarin Suwan, Sorawit Wainipitapong, Krasean Panyakhamlerd
Publikováno v:
The Journal of Sexual Medicine. 18:1299-1307
Background Spironolactone and cyproterone acetate are commonly used in feminizing hormone therapy to achieve the goal of female range testosterone level; however, the data on the efficacy comparing between these two anti-androgens are scarce. Aim To