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Publikováno v:
Journal of Applied Microbiology. 132:2121-2130
Aims Escherichia albertii is an emerging diarrheagenic pathogen causing food- and water-borne infection in humans. However, no selective enrichment broths for E. albertii have ever been reported. In this study, we tested several basal media, selectiv
Autor:
Russell R. Kempker, Charles A. Peloquin, Henry M. Blumberg, Zaza Avaliani, Jeffrey M. Collins, Shorena Sabanadze, Maia Kipiani, Mariam Gujabidze, Tinatin Bakuradze, Alison Smith, Mohammad H. Al-Shaer, Teona Avaliani
Publikováno v:
Clin Infect Dis
Background The ability of antituberculosis drugs to cross the blood–brain barrier and reach the central nervous system is critical to their effectiveness in treating tuberculosis meningitis (TBM). We sought to fill a critical knowledge gap by provi
Publikováno v:
American Journal of Health-System Pharmacy. 79:467-471
Purpose Stenotrophomonas maltophilia has emerged as a critical opportunistic pathogen associated with significant morbidity and mortality. Tetracycline derivatives have been recognized as alternative treatment options, but they have varied pharmacoki
Autor:
Sacha Flammier, Sandrine Lemoine, Justine Bacchetta, Laurence Dubourg, Laurence Chardon, Manon Aurelle
Publikováno v:
Nephrology Dialysis Transplantation. 37:2150-2156
Background The assessment of phosphate homeostasis in clinical practice relies not only on circulating phosphate levels but also on phosphate tubular reabsorption, ideally assessed using the tubular maximum phosphate reabsorption per glomerular filtr
Autor:
Josef S Smolen, Daniel Aletaha, Ruediger B Mueller, Manuel Bécède, Rudolf Puchner, Michael Bonelli, Paul Studenic, Martina Olejarova, Thomas Perkmann, Dmitry Karateev, Karel Pavelka, Andreas Kerschbaumer, Elisabeth Puchhammer-Stöckl, Carl-Walter Steiner, Martina Durechova, Michaela Loiskandl, Jutta Stieger, Gregor Bond, E. L. Luchikhina
Publikováno v:
Rheumatology. 61:2815-2825
Objectives RA patients who fail to respond to MTX can receive biologic dMARDs (bDMARDs). The Torque Teno Virus (TTV) is a potential novel candidate for monitoring of immunosuppression. We explore TTV in these patients and its association with clinica
Autor:
Kenji Tsukigawa, Keishi Yamasaki, Hakaru Seo, Masaki Otagiri, Koji Nishi, Kazuaki Taguchi, Keiki Sakurama
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:88-93
Objectives Echinocandins are widely used for the treatment of invasive fungal diseases. While they bind strongly to plasma proteins, our knowledge of this process is not sufficient to permit their pharmacokinetics and pharmacodynamics targets to be d
Autor:
Geraldine Cambridge, David A. Isenberg, Loren Kell, Samuel J Taylor, Maria J. Leandro, Kavina Shah, Ruth J Pepper, Venkat Reddy, Mark S. Cragg, Scott R. Henderson, Christian Klein
Publikováno v:
Rheumatology. 61:2894-2904
Objectives To investigate key factors that may contribute to the variability of rituximab-mediated peripheral and renal B cell depletion (BCD) in SLE. Methods We analysed: (i) CD19+ B cell counts in patients with SLE before and 1, 2, 3 and 6 months a
Publikováno v:
Nicotine & Tobacco Research. 24:581-589
Introduction Waterpipe smoking is gaining popularity and becoming a major global public health concern. An understanding of factors that predict waterpipe smoking cessation is necessary for targeting tobacco control efforts. Methods This is a seconda
Autor:
Gilles Peytavin, Florence Damond, Sophie Matheron, A. Bachelard, Samuel Lebourgeois, Gilles Collin, Charlotte Charpentier, Jade Ghosn, Quentin Le Hingrat, Diane Descamps, Valentine Marie Ferré
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:409-412
Background HIV-2 resistance to integrase strand-transfer inhibitors (INSTIs) is characterized by two main pathways: (i) mutations at codons 143, 148 and155; and (ii) amino acid insertion after integrase codon 231 (231ins). Objectives To complete INST
Publikováno v:
Rheumatology. 61:3071-3081
Objective To identify the role of fatty acid binding protein 3 (FABP3) in vascular fibrosis in Takayasu’s arteritis (TAK) and to explore the underlying molecular mechanism. Methods The expression of FABP3 and extracellular matrix proteins (ECMs) we