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Autor:
Daniel Wolff, Andreas Hiergeist, André Gessner, Joachim Hahn, Wolfgang Herr, Katja Dettmer, Markus Weber, Daniela Weber, Ernst Holler
Publikováno v:
Clinical Infectious Diseases. 68:1303-1310
Background Maintaining gastrointestinal (GI) microbiome diversity plays a key role during allogeneic stem cell transplantation (ASCT), and loss of diversity correlates with acute GI graft versus host disease (GvHD) and poor outcomes. Methods In this
Autor:
Kiyoshi Okazuka, Tadao Ishida
Publikováno v:
Japanese Journal of Clinical Oncology. 48:785-793
Therapeutic strategies for multiple myeloma have dramatically changed in the last two decades, especially after the introduction of proteasome inhibitors. The first-in-class proteasome inhibitor, bortezomib, was approved by the US Food and Drug Admin
Publikováno v:
Journal of Tropical Pediatrics. 65:264-272
Background: Methylxanthines have cardiac stimulant effects. The current study aimed to compare acute hemodynamic changes between caffeine and aminophylline in �34 weeks’ preterm neonates. Methods: The study was performed using information on echo
Publikováno v:
Journal of Antimicrobial Chemotherapy, 73(11), 2916-2926. Oxford University Press
Nitrofurantoin and nitroxoline are oral antibiotics for the treatment or prophylaxis of acute urinary tract infections. New interest in both these drugs is increasing because of the emergence of resistance to other antibiotics, but knowledge of their
Autor:
Abhijit Takawale, Marc-Antoine Gillis, Xiao-Yan Qi, Nipon Chattipakorn, Jean-Claude Tardif, Stanley Nattel, Yu Chen, Mona Aflaki, Sirirat Surinkaew, Yanfen Shi
Publikováno v:
Cardiovascular Research. 115:94-106
Aims Heart failure (HF) produces left atrial (LA)-selective fibrosis and promotes atrial fibrillation. HF also causes adrenergic activation, which contributes to remodelling via a variety of signalling molecules, including the exchange protein activa
Autor:
Yuan-Yang Lai, Kung-Chiao Hsieh, Jerome M. Siegel, Lalini Ramanathan, Yu-Hsuan Cheng, Keng-Tee Chew, Darian Nguyen
Publikováno v:
Sleep
Study ObjectivesRestless legs syndrome (RLS) has been hypothesized to be generated by abnormal striatal dopamine transmission. Dopaminergic drugs are effective for the treatment of RLS. However, long-term use of dopaminergic drugs causes adverse effe
Autor:
Peter T. Donnan, Charis Marwick, Samira Bell, Tobias Dreischulte, Trijntje J.W. Rennie, Peter Davey, Nicosha De Souza
Publikováno v:
Nephrology Dialysis Transplantation. 34:1910-1916
Background Development of acute kidney injury (AKI) following the use of antibiotics such as sulphonamides, trimethoprim and aminoglycosides is a frequently described phenomenon. More recently, an association between fluoroquinolone use and AKI has b
Autor:
Daria B. Trushina, Georgy I. Kovalev, Tatiana Borodina, Irina I. Marchenko, Evgeny A. Kondrakhin, Yulia A. Volkova, Igor V. Zavarzin, Valerii Z. Shirinian, Mikhail V. Kovalchuk, Tatiana Bukreeva
Publikováno v:
Journal of Pharmacy and Pharmacology. 70:1164-1173
Objectives Anxiolytic drug zolpidem was incorporated into the microcontainers based on mesoporous calcium carbonate particles modified by diethylaminoethyl-dextran/hyaluronic acid shell. The release of zolpidem in saline solution and in polymer film
Autor:
Guy L. Weinberg, Matthew Lindeblad, Richard B. van Breemen, Kamil Gierszal, Douglas L. Feinstein, Israel Rubinstein, Aleksander V. Lyubimov
Publikováno v:
Toxicological Sciences. 165:389-395
Patients exposed to long acting anticoagulant rodenticides (LAARs) are typically administered large amounts of oral vitamin K1 (VK1) to counteract life-threatening anticoagulant effects. Although VK1 treatment effectively prevents mortality, addition
Autor:
Walter Ageno, Beverley J. Hunt
Publikováno v:
European Heart Journal Supplements : Journal of the European Society of Cardiology
Hospitalized acute medically ill patients are vulnerable to venous thromboembolism (VTE), known as hospital-acquired thrombosis (HAT). The elevated risk of HAT is usually due to a combination of factors, with immobility and a prothrombotic state due