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Publikováno v:
Journal of Applied Microbiology. 132:2262-2269
Aims Dietary protein, as an important macronutrient, widely participates in host growth and metabolism. In this study, effects of different protein levels (14, 20 and 26%) on the gut development, microbial compositions and mucin expressions were stud
Publikováno v:
Human Molecular Genetics. 31:1417-1429
The common null polymorphism (R577X) in the ACTN3 gene is present in over 1.5 billion people worldwide and results in the absence of the protein α-actinin-3 from the Z-discs of fast-twitch skeletal muscle fibres. We have previously reported that thi
Autor:
Kim Brint Pedersen, Jin-Ran Chen, Vasilis Vasiliou, Cole Maimone, Michelle L. Osborn, Shana Littleton, James Watt, Allison R Norman, Martin J. J. Ronis, Alexandra Denys
Publikováno v:
Toxicol Sci
Excessive ethanol consumption is a risk factor for osteopenia. Since a previous study showed that transgenic female mice with overexpression of catalase are partially protected from ethanol-mediated trabecular bone loss, we investigated the role of e
Autor:
Roberta J. Ward, Abdelkader Dahchour
Publikováno v:
Alcohol and Alcoholism. 57:165-175
Aims The purpose of this review is to evaluate microdialysis studies where alterations in the dopaminergic system have been evaluated after different intoxication states, in animals showing preference or not for alcohol, as well as during alcohol wit
Autor:
Tomoya Sano, Tadahiro Shinozawa, Takeshi Watanabe, Hironobu Yasuno, Yasushi Masuda, Masaaki Kakehi
Publikováno v:
Toxicological Sciences
Neurotoxicity is a principal concern in nonclinical drug development. However, standardized and universally accepted fluid biomarkers for evaluating neurotoxicity are lacking. Increasing clinical evidence supports the potential use of neurofilament l
Autor:
Thaigra Souza Soares, Antonio Marcus de Andrade Paes, Franciane Quintanilha Gallego Souza, Rafaianne Queiroz Moraes Souza, Yuri Karen Sinzato, Débora Cristina Damasceno, José Eduardo Corrente, Verônyca Gonçalves Paula, Barshana Karki, Gustavo Tadeu Volpato
Publikováno v:
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-28T17:22:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-20 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) We evaluated the influence of the hyperglycemic intrauterine environment an
Autor:
Kazunori Hamamura, Takuma Sato, Ken Miyazawa, Kenjiro Tanaka, Akifumi Togari, Hisataka Kondo, Kaori Hayashi, Eiichiro Ariji, Mayo Kondo, Shigemi Goto, Takao Hirai, Yoshiko Ariji, Sae Kusafuka, Daisuke Kodama
Publikováno v:
European Journal of Orthodontics. 44:404-411
Summary Objectives Orthodontic tooth movement (OTM) increases sympathetic and sensory neurological markers in periodontal tissue. However, the relationship between the sympathetic and sensory nervous systems during OTM remains unclear. Therefore, the
Autor:
Koichi Yano, Makoto Ikenoue, Naohiro Sugita, Deokcheol Lee, Narantsog Choijookhuu, Noboru Taniguchi, Fidya, Etsuo Chosa, Yoshitaka Hishikawa
Publikováno v:
Biology of Reproduction. 105:1510-1520
High-mobility group box 2, a chromatin-associated protein that interacts with deoxyribonucleic acid, is implicated in multiple biological processes, including gene transcription, replication, and repair. High-mobility group box 2 is expressed in seve
Autor:
Berta Victoria, Andrzej Bartke, Erin R. Hascup, Maria Isabel Schiavon Cousen, Justin Darcy, Samuel McFadden, Kevin N. Hascup, Michal M. Masternak, Yimin Fang, Adam Gesing, Augusto Schneider
Publikováno v:
J Gerontol A Biol Sci Med Sci
Growth hormone receptor knockout (GHRKO) mice are smaller, long living, and have an increased metabolic rate compared with normal (N) littermates. However, it is known that thermoneutral conditions (30–32°C) elicit metabolic adaptations in mice, i
Publikováno v:
The Journals of Gerontology: Series A. 77:424-432
Nitric oxide (NO)-mediated vasodilatation is a fundamental response of vasculature, however, regulation of NO signaling pathway on resistance vessels in the older adult with hypertension is still unclear. The 16-week-spontaneously hypertensive rats (