Zobrazeno 1 - 10
of 1 521
pro vyhledávání: ''
Autor:
Jessica J Jowais, Marina Rieder, Lucilla Giammarino, Katja E. Odening, Michael Brunner, Christoph Bode, Sara I. Liin, Alessandro Castiglione, Manfred Zehender, Stefanie Perez-Feliz, Eike M. Wülfers, Gideon Koren, Hans Peter Larsson, Tibor Hornyik, István Baczkó, Iask Edler, András Varró, Zsuzsanna Bősze
Publikováno v:
Europace
Aim Long QT syndrome (LQTS) is a cardiac channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Since current therapies often fail to prevent arrhythmic events in certain LQTS subtypes, new therapeutic strategies are needed.
Autor:
G J du Marchie Sarvaas, Ella M. Poels, Paula A. da Costa Martins, Rudolphus Berger, Lara Ottaviani, C Dos Remedios, F S De Man, L. J. de Windt, Anne-Marie C. Koop, André Lourenço, K W Van De Kolk, Diana S. Nascimento, Jordy M. M. Kocken, Raquel Figuinha Videira, P. Mendes-Ferreira, Aida Llucià-Valldeperas, Inês Falcão-Pires
Publikováno v:
Cardiovascular Research, 118(12), 2688-2702. Oxford University Press
Videira, R F, Koop, A M C, Ottaviani, L, Poels, E M, Kocken, J M M, Dos Remedios, C, Mendes-Ferreira, P, van de Kolk, K W, du Marchie Sarvaas, G J, Lourenço, A, Llucià-Valldeperas, A, Nascimento, D AS, de Windt, L J, de Man, F S, Falcão-Pires, I, Berger, R M F & da Costa Martins, P A 2022, ' The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload ', Cardiovascular Research, vol. 118, no. 12, pp. 2688-2702 . https://doi.org/10.1093/cvr/cvab299, https://doi.org/10.1093/cvr/cvab299
Videira, R F, Koop, A M C, Ottaviani, L, Poels, E M, Kocken, J M M, Dos Remedios, C, Mendes-Ferreira, P, van de Kolk, K W, du Marchie Sarvaas, G J, Lourenço, A, Llucià-Valldeperas, A, Nascimento, D AS, de Windt, L J, de Man, F S, Falcão-Pires, I, Berger, R M F & da Costa Martins, P A 2022, ' The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload ', Cardiovascular Research, vol. 118, no. 12, pp. 2688-2702 . https://doi.org/10.1093/cvr/cvab299, https://doi.org/10.1093/cvr/cvab299
Aims Research on the pathophysiology of right ventricular (RV) failure has, in spite of the associated high mortality and morbidity, lagged behind compared to the left ventricle (LV).Previous work from our lab revealed that the embryonic basic helix-
Autor:
Xiaoli Luo, Pedro A. Jose, Caiyu Chen, Xue Gong, Cong Lan, Cheng Yu, Cuimei Hu, Chao Fan, Zaicheng Xu, Chunyu Zeng, Jialiang Wang, Hao Luo
Publikováno v:
Cardiovasc Res
Aims Exposure to maternal diabetes is associated with increased prevalence of hypertension in the offspring. The mechanisms underlying the prenatal programming of hypertension remain unclear. Because endoplasmic reticulum (ER) stress plays a key role
Autor:
Hind Lal, Qinkun Zhang, Beth Weber, Sidney L. Satterfield, Guy Salama, Michael S Glennon, Jason R Becker, Soumojit Pal, Eric J Hall, Puneeth Shridhar
Publikováno v:
Cardiovasc Res
Aims The cardiac natriuretic peptides (atrial natriuretic peptide [ANP] and B-type natriuretic peptide [BNP]) are important regulators of cardiovascular physiology, with reduced natriuretic peptide (NP) activity linked to multiple human cardiovascula
Autor:
Ulrich Kintscher, Nicola Wilck, Arne Thiele, Hendrik Bartolomaeus, Anna Katharina Migglautsch, Elia Smeir, Robert Klopfleisch, Jana Grune, Michael Schupp, Katja Luettges, Michael Rothe, Rolf Breinbauer, Daniel Ritter, Erin E. Kershaw, Anna Foryst-Ludwig, Gernot F. Grabner, Niklas Beyhoff, Julia S. Steinhoff, Rudolf Zechner
Publikováno v:
Cardiovasc Res
Aims Heart failure (HF) is characterized by an overactivation of β-adrenergic signaling that directly contributes to impairment of myocardial function. Moreover, β-adrenergic overactivation induces adipose tissue lipolysis, which may further worsen
Autor:
Yasuko K Bando, Rei Shibata, Tomonobu Takikawa, Yuta Ozaki, Koji Ohashi, Lixin Fang, Noriyuki Ouchi, Katsuhiro Kato, Yuuki Shimizu, Hiroshi Kawanishi, Hayato Ogawa, Mikito Takefuji, Toyoaki Murohara, Naoya Otaka, Mizuho Hiramatsu-Ito
Publikováno v:
Cardiovascular Research. 118:1597-1610
Aims Abdominal aortic aneurysm (AAA) is an increasing and life-threatening disease. Obesity contributes to an increased risk of AAA. Omentin is a circulating adipokine, which is downregulated in obese complications. Here, we examined whether omentin
Publikováno v:
Cardiovascular Research
Despite significant advances in its detection, understanding and management, atrial fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on morbidity and mortality of millions of patients. AF results from complex, dynam
Publikováno v:
Cardiovascular Research. 118:1126-1137
Aims Cardiomyocyte Ca2+ homoeostasis is altered with ageing and predisposes the heart to Ca2+ intolerance and arrhythmia. Transient receptor potential vanilloid 4 (TRPV4) is an osmotically activated cation channel with expression in cardiomyocytes of
Autor:
Gaspare Mostacciuolo, Claudio Bussadori, Shih-Che Hsu, E. Boz, Claudia Altomare, Martina Arici, Gwo-Jyh Chang, Marcella Rocchetti, Giuseppe Bianchi, Alessandra Maria Lodrini, Emanuela Sala, Paolo Barassi, Mara Ferrandi, Sara Vagni, Patrizia Ferrari, Eleonora Torre
Publikováno v:
Cardiovascular Research. 118:1020-1032
Aims Diabetic cardiomyopathy is a multifactorial disease characterized by an early onset of diastolic dysfunction (DD) that precedes the development of systolic impairment. Mechanisms that can restore cardiac relaxation improving intracellular Ca2+ d
Autor:
Bernd Hewing, Karl Stangl, Verena Stangl, Andrea Weller, Jana Grune, Carmen Hannemann, Edward A. Fisher, Antje Ludwig, Alica Brettschneider, Nicole Rösener, Johannes H Schecker
Publikováno v:
Cardiovasc Res
Aims Atherosclerosis is a chronic inflammatory disease of the arterial vessel wall and anti-inflammatory treatment strategies are currently pursued to lower cardiovascular disease burden. Modulation of recently discovered inactive rhomboid protein 2