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Autor:
Jennie Taylor, Gayathri Warrier, Helen M. Hansen, Pranathi Chunduru, Annette M. Molinaro, Ji Yoon Lee, Sean Lee, Brock C. Christensen, Paige M. Bracci, Karl T. Kelsey, Joaquin Anguiano, Devin C. Koestler, Margaret Wrensch, John K. Wiencke, Lucie McCoy, Jennifer Clarke, Lucas A. Salas, Terri Rice
Publikováno v:
Journal of the National Cancer Institute, vol 114, iss 3
J Natl Cancer Inst
J Natl Cancer Inst
Background Tumor-based classification of human glioma portends patient prognosis, but considerable unexplained survival variability remains. Host factors (eg, age) also strongly influence survival times, partly reflecting a compromised immune system.
Autor:
Rui Liang, Jianyu Wang, Shusen Wang, Jing Yang, Ming Liu, Na Li, Jinyang Zhen, Yumeng Huang, Tengli Liu
Publikováno v:
European Journal of Endocrinology. 185:565-576
Objective Progressive beta-cell dysfunction is a hallmark of type 2 diabetes (T2D). Increasing evidence indicates that over-stimulating proinsulin synthesis causes proinsulin misfolding and impairs insulin maturation and storage in db/db mice. Howeve
Autor:
Brenda Su Ping Lim, S. Sendhil Velan, Navin Michael, Priya Govindharajulu, Siew Pang Chan, Christiani Jeyakumar Henry, Melvin Khee-Shing Leow, Suresh Anand Sadananthan, Wai Han Hoi, Yingshan Lee, Timothy Peng Lim Quek, Shaikh A K K Abdul Shakoor, Pei Shan Yeo, Yaligar Jadegoud, Daniel Ek Chew, Huiling Liew, Sanjay Kumar Verma, Hui Jen Goh, Rinkoo Dalan, Lijuan Sun, Chee Kian Chew
Publikováno v:
European Journal of Endocrinology
Objective Brown adipose tissue (BAT) controls metabolic rate through thermogenesis. As its regulatory factors during the transition from hyperthyroidism to euthyroidism are not well established, our study investigated the relationships between suprac
Publikováno v:
The Journal of Infectious Diseases. 224:S443-S451
This manuscript describes the history, background, and current structure of the United States Immunization Program, founded upon public- and private-sector partnerships that include federal agencies, state and local health departments, tribal nations
Autor:
Shannon R. Miles, Risa Nakase Richardson, Heather G. Belanger, Kristen Dams-O'Connor, Laura Bajor, Marc A. Silva, Tea Reljic, Amanda Garcia
Publikováno v:
Military Medicine. 187:1412-1421
Introduction Special Operations Forces (SOF) personnel are at increased risk for traumatic brain injury (TBI), when compared with conventional forces (CF). Prior studies of TBI in military samples have not typically investigated SOF vs. CF as specifi
Autor:
Yong Pil Chong, Seongman Bae, Sang-Ho Choi, Min Jae Kim, Sung-Han Kim, Moonsuk Bae, Yang Soo Kim, Yunseo Jeong, Jiwon Jung, Sang-Oh Lee
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:223-228
Background The optimal duration of antimicrobial therapy for uncomplicated Pseudomonas aeruginosa bloodstream infection (BSI) is unknown. We compared the outcomes of short and prolonged courses of antimicrobial therapy in adults with uncomplicated ps
Autor:
Saraschandra Vallabhajosyula, Rajkumar Doshi, Ardaas Kanwar, Sri Harsha Patlolla, Pranathi R Sundaragiri, Wisit Cheungpasitporn, Singh Mandeep
Publikováno v:
QJM: An International Journal of Medicine. 115:530-536
Summary Background There are limited data on the influence of seasons on the outcomes of acute myocardial infarction-cardiac arrest (AMI-CA). Aim To evaluate the outcomes of AMI-CA by seasons in the United States Design Retrospective cohort study Met
Publikováno v:
Family Practice. 39:610-615
In order to integrate genomic medicine into routine patient care and stratify personal risk, it is increasingly important to record family history (FH) information in general/family practice records. This is true for classic genetic disease as well a
Autor:
Steen Hoffmann, Palle Valentiner-Branth, Håkon Sandholdt, Lene Fogt Lundbo, Thomas Benfield, Lars Smith-Hansen, Zitta Barrella Harboe
Publikováno v:
Clinical Infectious Diseases. 75:125-130
Background Risk of invasive meningococcal disease (IMD) is increased in patients with complement deficiency and human immunodeficiency virus (HIV) infection. Risk associated with comorbidity is not well described. Methods This was a nationwide adult
Autor:
Azim Pothiawala, Leomar Y. Ballester, Meenakshi B. Bhattacharjee, Cole T. Lewis, Antonio Dono, Nitin Tandon
Publikováno v:
J Neuropathol Exp Neurol
Meningioangiomatosis (MA) is a rare process at the intersection of cerebral developmental and neoplastic disorders that often results in epilepsy. We evaluated molecular alterations in MA to characterize its biology and pathogenesis. We searched a co