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Publikováno v:
J Natl Cancer Inst
Background Incidence of estrogen receptor (ER)-negative breast cancer, an aggressive subtype, is highest in US African American women and in Southern residents but has decreased overall since 1992. We assessed whether ER-negative breast cancer is dec
Autor:
Yolanda M Lenzy, Patricia F. Coogan, Lynn Rosenberg, Yvette C. Cozier, Julie R. Palmer, Kimberly A. Bertrand
Publikováno v:
Carcinogenesis
Hair relaxers and leave-in conditioners and oils, commonly used by Black/African American women, may contain estrogens or estrogen-disrupting compounds. Thus, their use may contribute to breast cancer risk. Results of the few previous studies on this
Autor:
Ava Kwong, Cuizhi Geng, Qingyuan Zhang, Donggeng Liu, Ning Liao, Wei Li, Zhimin Shao, Da Pang, Youngsen Yang, Ling-Ming Tseng, Chiun-Sheng Huang, Binghe Xu
Publikováno v:
Japanese Journal of Clinical Oncology. 51:345-353
Background The addition of pertuzumab to trastuzumab plus standard chemotherapy as adjuvant therapy following surgery significantly improved invasive disease-free survival (IDFS) in patients with HER2-positive early breast cancer in the multinational
Autor:
Yaara Ber, David Margel, Rachel Ozlavo, Rinat Yerushalmi, Ahuvah Grubsrein, Adi Pomerantz, Tuval Sivan, Sharon Bargil, Yael Rapson, Eran Sharon, Opher Caspi, Daliah Tsoref
Publikováno v:
Carcinogenesis
Women who carry the BRCA mutation are at high lifetime risk of breast cancer, but there is no consensus regarding an effective and safe chemoprevention strategy. A large body of evidence suggests that 3,3-diindolylmethane (DIM), a dimer of indole-3-c
Autor:
Giulia Viale, Veronica Zuber, Patrizia Zucchinelli, Giovanna Petrella, Nadia Di Muzio, Luca Licata, Oreste Gentilini, Pietro Panizza, Maria Grazia Rodighiero, Daniela Aldrighetti, Lorenzo Sica, Rosa Di Micco, Giampaolo Bianchini, Alessia Rognone, Stefania Zambelli, M. Pasetti, Stefano Cascinu, Isabella Sassi
Publikováno v:
The Oncologist
Northern Italy has been one of the European regions reporting the highest number of COVID‐19 cases and deaths. The pandemic spread has challenged the National Health System, requiring reallocation of most of the available health care resources to t
Autor:
Clément Barjon, Didier Pourquier, Florence Boissière-Michot, Nathalie Bonnefoy, Virginie Lafont, Evelyne Lopez-Crapez, Cécile Dejou, Ghita Chabab, Henri-Alexandre Michaud, William Jacot, Naoill Abdellaoui, Lucie Salvador-Prince
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, In press, ⟨10.1002/JLB.3MA0420-278RR⟩
Journal of Leukocyte Biology, Society for Leukocyte Biology, In press, ⟨10.1002/JLB.3MA0420-278RR⟩
γδ T cells contribute to the immune response against many cancers, notably through their powerful effector functions that lead to the elimination of tumor cells and the recruitment of other immune cells. However, their presence in the tumor microen
Autor:
Jeong Eon Lee, Byung Joo Chae, Jonghan Yu, Jai Min Ryu, Seok Jin Nam, Seok Won Kim, Se Kyung Lee
Publikováno v:
Japanese Journal of Clinical Oncology. 50:104-113
Objective Demands for genetic counseling with BRCA1/2 examination have markedly increased. Accordingly, the incidence of uninformative results on BRCA1/2 mutation status has also increased. Because most patients examined for BRCA1/2 mutation have a h
Autor:
Norikazu Masuda, Nobuaki Sato, Shoichiro Ohtani, Nobuki Matsunami, Masahiro Kashiwaba, Jun Yamamura, Takayuki Ueno, Satoshi Morita, Masato Takahashi, Shinji Ohno, Toshimi Takano, Masakazu Toi, Koji Kaneko
Publikováno v:
Japanese Journal of Clinical Oncology
Background The original aim of this study was to evaluate the treatment sequence and anthracycline requirement in docetaxel, cyclophosphamide and trastuzumab therapy. After one death in the anthracycline-containing arm, the protocol was amended to te
Autor:
Kumar Abhishek, Sherri Z. Millis, Venkataprasanth P. Reddy, Katherine A. Janeway, Jeffrey S. Ross, Breelyn A. Wilky, Phil Stephens, Ethan Sokol, Umut Disel, Mehmet Akif Ozturk, Alexa B. Schrock, Sumanta K. Pal, Viola W. Zhu, Mrinal M. Gounder, Sai-Hong Ignatius Ou, Samuel J. Klempner, Chaitali Singh Nangia, Ruben Cabanillas, Vincent A. Miller, Nuri Karadurmus, Jennifer Webster, Jon Chung, Christine M. Lovly, Shridar Ganesan, Lee A. Albacker, Salil Soman, Asli O. Matos, Adam Benson, Garrett M. Frampton, Sally E. Trabucco, Russell Madison, Siraj M. Ali, Semra Paydas
Publikováno v:
The oncologist, vol 25, iss 1
The Oncologist
The Oncologist
Purpose Amplifications of receptor tyrosine kinases (RTKS) are therapeutic targets in multiple tumor types (e.g. HER2 in breast cancer), and amplification of the chromosome 4 segment harboring the three RTKs KIT, PDGFRA, and KDR (4q12amp) may be simi
Autor:
Zoe Guan, Giovanni Parmigiani, Suzanne B. Coopey, Ahmet Acar, Kevin S. Hughes, Molly Griffin, Anne Marie McCarthy, Alan Semine, Dorothy A. Sippo, Zhengyi Deng, Michaela Welch, Danielle Braun
Publikováno v:
J Natl Cancer Inst
Background Several breast cancer risk-assessment models exist. Few studies have evaluated predictive accuracy of multiple models in large screening populations. Methods We evaluated the performance of the BRCAPRO, Gail, Claus, Breast Cancer Surveilla