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Autor:
Jacqueline McBride, Bartosz Korczowksi, K T Park, Gaohong She, Astrid Scalori, Regan Li, Jaroslaw Kierkus, Franklin Fuh, AK Kadva, Mariam Abouhossein, Meina Tao Tang, Wenhui Zhang
Publikováno v:
Inflammatory Bowel Diseases. 28:1348-1356
Background Etrolizumab, a humanized anti-β7 antibody, has not been studied in children. Here, we evaluate the pharmacokinetics, pharmacodynamics, and safety of etrolizumab in children with inflammatory bowel disease. Methods Patients age 4 to 17 yea
Autor:
Ayşegül İnci Sezen, Cemal Aker, Levent Cansever, Muzaffer Metin, Mehmet Ali Bedirhan, Celal Bugra Sezen, Mustafa Vedat Dogru, Merve Özbek
Publikováno v:
Interactive Cardiovascular and Thoracic Surgery
OBJECTIVES In this study, we aimed to establish risk factors for primary spontaneous pneumomediastinum associated with Coronavirus disease 2019 (COVID-19) and reveal those which are significant. METHODS The study included 62 patients with primary spo
Autor:
Jonathan I. Silverberg, Donald Lei, Rajeev Chavda, S Gabriel, Adnan Ahmed, Gabrielle Schwartzman
Publikováno v:
Clinical and Experimental Dermatology. 47:359-372
Background The real-world course of health-related quality of life (HRQoL) in atopic dermatitis (AD) is not well established. Aim To examine predictors, longitudinal course and phenotypes of HRQoL in adult patients with AD. Methods This was a prospec
Autor:
Gary Butler, Mehul Dattani, Leo Dunkel, Helen L Storr, Kausik Banerjee, Tansit Saengkaew, Heena R Patel, Ruben H Willemsen, Michael McGuigan, Sasha Howard
Publikováno v:
European Journal of Endocrinology
Context Pubertal delay can be the clinical presentation of both idiopathic hypogonadotropic hypogonadism (IHH) and self-limited delayed puberty (SLDP). Distinction between these conditions is a common but important diagnostic challenge in adolescents
Autor:
Silvia Modamio-Høybjør, Isabel González-Casado, Angel Campos-Barros, Francisca Díaz-González, José Antonio Bermúdez de la Vega, Fernando Santos-Simarro, Atilano Carcavilla, Ana C Barreda-Bonis, Carolina de la Torre, Purificación Ros-Pérez, Inés Mulero-Collantes, Sara Benito-Sanz, Angela del Pozo, Mario Solís, Jesús González de Buitrago Amigo, Julián Nevado, Lucia Sentchordi-Montané, André M. Travessa, Pablo Prieto, Miriam Aza-Carmona, Pilar Bahíllo-Curieses, Elena Vallespín, Jaime Cruz-Rojo, Manuel Parrón-Pajares, Joaquín Ramírez-Fernández, Karen E. Heath, Pablo Ruiz-Ocaña, Carlos Goetz, Carolina Bezanilla-López
Publikováno v:
European Journal of Endocrinology. 185:691-705
Objective Next generation sequencing (NGS) has expanded the diagnostic paradigm turning the focus to the growth plate. The aim of the study was to determine the prevalence of variants in genes implicated in skeletal dysplasias in probands with short
Publikováno v:
European Journal of Endocrinology. 185:629-635
Objective The diagnosis of growth hormone deficiency (GHD) in children is not always straightforward because insulin-like growth factor 1 (IGF-I) or GH stimulation tests may not be able to discriminate GHD from constitutional delay of growth and pube
Publikováno v:
International Journal of Epidemiology. 51:749-758
Background We aimed to study whether pre-eclampsia is associated with childhood asthma, allergic and non-allergic asthma, accounting for family factors and intermediate variables. Methods The study population comprised 779 711 children born in 2005
Autor:
B. Ganatra, R. Amarnani, Y. Alfallouji, K. Dear, E. Twigg, J. P. Westwood, B. Goulden, V. Morris, T. Hillman, S. Goolamali, Z. Naderi, R. Sidwell, P. Ellery, E. Calonje, G. Kravvas, C. B. Bunker
Publikováno v:
Clinical and Experimental Dermatology
Acute pseudoperniosis (PP) has a recognized association with COVID-19 and tends to occur without cold precipitation in young, healthy patients, often without a clear history of COVID-19. These lesions usually resolve within 2 weeks and without long-t
Autor:
John Jims Veeravalli, Li-Tzu Wang, Eshwar Thota, Monica Maria Illescas Ralda, Chia-Tze Kao, Kevin Sheng-Kai Ma, James Cheng-Chung Wei, Cory M. Resnick, Jing-Yang Huang
Publikováno v:
European Journal of Orthodontics. 44:226-231
Summary Background and objectives Juvenile idiopathic arthritis (JIA), an autoimmune disease, has been proposed to be comorbid with obstructive sleep apnoea (OSA). We aimed at testing the hypothesis that patients with JIA may presented with high risk
Autor:
Hui Zhang, Erin MacArthur, Valerie McLaughlin Crabtree, Haitao Pan, Matthew W. Wilson, Alberto S. Pappo, Kayla N. LaRosa, Fang Wang, Jane Brigden
Publikováno v:
Journal of Pediatric Psychology. 47:306-317
Objective Secondary outcomes from a published feasibility and acceptability trial were examined to explore the effect of bright white light (BWL) on quality of life (QoL) and depressive symptoms compared to dim red light (DRL) control in adolescents