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Autor:
Azim Pothiawala, Leomar Y. Ballester, Meenakshi B. Bhattacharjee, Cole T. Lewis, Antonio Dono, Nitin Tandon
Publikováno v:
J Neuropathol Exp Neurol
Meningioangiomatosis (MA) is a rare process at the intersection of cerebral developmental and neoplastic disorders that often results in epilepsy. We evaluated molecular alterations in MA to characterize its biology and pathogenesis. We searched a co
Autor:
John W. Prineas, John Parratt
Publikováno v:
Journal of Neuropathology and Experimental Neurology
This study examined the roles of microglia and monocytes in myelin destruction in patients with early multiple sclerosis (MS). Twenty-two cases were studied; the clinical duration was
Publikováno v:
American Journal of Clinical Pathology. 157:202-211
Objectives In this retrospective study, we report a series of benign lymph nodes showing small populations of normal B-cell precursors characterized by flow cytometry and immunohistochemistry. Methods Ten cases identified during clinical flow cytomet
Autor:
Katsushi Igarashi, Masanori Fujimoto, Hisashi Koide, Tomohiko Ichikawa, Kumiko Naito, Yutarou Ruike, Shinichi Sakamoto, Sawako Suzuki, Yusuke Imamura, Jun-ichiro Ikeda, Akiko Ishida, Kazuki Ishiwata, Hanna Deguchi-Horiuchi, Koutaro Yokote
Publikováno v:
European Journal of Endocrinology. 185:155-165
Introduction Although 18F-FDG PET was originally developed to evaluate benign and malignant tumors, the frequency of detection of benign adrenocortical adenomas showing FDG-PET accumulation has increased. However, the details of FDG-PET-accumulated b
Autor:
Margaret Fink, Carsten G. Bönnemann, Gina Norato, Diana Bharucha-Goebel, Sandra Donkervoort, A. Reghan Foley, G. Averion, Victoria Biancavilla, Sarah Debs, Dimah Saade, Eduardo Paredes, Ying Hu, Minal S. Jain, Rupleen Kaur, Wadih M. Zein, Diane Armao, M. Waite, Steven J. Gray, Tanya J. Lehky
Publikováno v:
Brain
Giant axonal neuropathy (GAN) is an ultra-rare autosomal recessive, progressive neurodegenerative disease with early childhood onset that presents as a prominent sensorimotor neuropathy and commonly progresses to affect both the peripheral nervous sy
Autor:
Xiao Xiao, Hongqi Zhang, Gao Zeng, Xinru Xiao, Jie Tang, Guilin Li, Jian Ren, Yuru Zong, Wei Yukui, Yibo Wang, Nan Jiang, Jiantao Liang, Shan Yongzhi, Peng Hu, Ming Ye, Zqi Kou, Jian Zou, Hao Wu, Bing Cui, Guolu Meng, Liyong Sun, Zan Chen, Tao Hong, Rutai Hui
Publikováno v:
Brain. 144:2648-2658
Cavernous malformations affecting the CNS occur in ∼0.16–0.4% of the general population. The majority (85%) of cavernous malformations are in a sporadic form, but the genetic background of sporadic cavernous malformations remains enigmatic. Of th
Autor:
Catalina Amador, Andrew L. Feldman
Publikováno v:
American Journal of Clinical Pathology. 155:479-497
ObjectivesThis review describes our approach to the diagnosis of all 4 anaplastic large cell lymphoma (ALCL) entities.MethodsALCLs are a group of CD30-positive mature T-cell lymphomas with similar morphologic and phenotypic characteristics but variab
Publikováno v:
Am J Clin Pathol
Objectives The SWI/SNF complex core subunit SMARCB1 is inactivated in a variety of neoplasms that share characteristic “rhabdoid” cytomorphology. The aim of this study was to evaluate SMARCB1-deficient soft tissue neoplasms on cytology to identif
Autor:
Johannes A. Hainfellner, Victoria-Elisabeth Gruber, Thomas Czech, Angelika Mühlebner, Martha Feucht, Gregor Kasprian, Theresa Scholl, Lisette Hoogendijk, Eleonora Aronica, Sharon Samueli, Roy J. Reinten, Reinhard Lehner
Publikováno v:
Journal of neuropathology and experimental neurology, 80(3), 274-282. Lippincott Williams and Wilkins
Complex cortical malformations (CCMs), such as hemimegalencephaly and polymicrogyria, are associated with drug-resistant epilepsy and developmental impairment. They share certain neuropathological characteristics including mammalian target of rapamyc
Autor:
Claudia Kronnerwetter, Barbara Kornek, Assunta Dal-Bianco, Paulus S. Rommer, Fritz Leutmezer, Günther Grabner, Gregor Kasprian, Thomas Berger, Hans Lassmann, Simon Hametner, Michael Weber, Siegfried Trattnig
Publikováno v:
Brain. 144:833-847
Recent data suggest that multiple sclerosis white matter lesions surrounded by a rim of iron containing microglia, termed iron rim lesions, signify patients with more severe disease course and a propensity to develop progressive multiple sclerosis. S