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Autor:
Mary W Montgomery, Bianca Martin, Christin N. Price, Daniel Solomon, Jennifer A A Johnson, Joji Suzuki
Publikováno v:
Open Forum Infectious Diseases
Background While there is a growing body of evidence that suggests outpatient parental antibiotic treatment (OPAT) for people who inject drugs (PWID) may be safe, research on integrating OPAT with addiction treatment for PWID has been limited. Method
Publikováno v:
Open Forum Infectious Diseases
Background Antimicrobial stewardship (AS) efforts have led to improved patient outcomes, reduction in unnecessary costs, and decrease in antimicrobial resistance (AR). Loyola University Medical Center (LUMC) is a quaternary care system that has prima
Publikováno v:
Open Forum Infectious Diseases
Background An antibiotic stewardship program (ASP) is critical to ensure the appropriateness of treatment for infections and to help avert Clostridium difficile infection (CDI). In a three-hospital system, infection preventionists (IP) found that hos
Autor:
Raymond Lamore Iii, Wei Hsiang Lin, Christo Cimino, Jimish Mehta, Amanda Binkley, Naasha J Talati
Publikováno v:
Open Forum Infectious Diseases
Background Adverse drug events are associated with an increase in hospital stay and cost. Risks from these events are minimized by adjusting a medication’s dose or frequency, and changes in renal function may necessitate adjustments. Currently, the
Publikováno v:
Open Forum Infectious Diseases
Background Hospital-acquired CDI contribute to significant morbidity, mortality, and cost burden in hospitalized patients. Clinical practice guidelines recommend strict testing criteria when employing nucleic acid amplification testing alone as to no
Publikováno v:
Open Forum Infectious Diseases
Background Patients frequently remain in the hospital for prolonged intravenous (IV) antibiotic therapy for serious infections when outpatient IV antibiotic therapy is unsafe or unfeasible. A protocol was developed to facilitate early discharge by ad
Publikováno v:
Open Forum Infectious Diseases
Background The annual incidence of invasive β-hemolytic group A streptococcus (GAS) infections in the United States is approximately 3.8 cases per 100,000 patients with 10–30% mortality. But data in GAS orthopedic infections is limited. We sought
Autor:
Jeremy J Frens, Erin Deja
Publikováno v:
Open Forum Infectious Diseases
Background Sepsis mortality is greatly affected by the timely receipt of appropriate antibiotics. FilmArray Blood Culture Identification (BCID) is used at Cone Health to identify organisms in blood cultures within one to 2 hours after growth detected
Autor:
Amy Parks Taylor, Kurt B. Stevenson, Erica E Reed, Kelci E Coe, Lynn Wardlow, Zeinab El Boghdadly
Publikováno v:
Open Forum Infectious Diseases
Background The Infectious Diseases Society of America’s guideline for implementing antibiotic (abx) stewardship recommends routine review of abx use. Several studies demonstrate antibiotic time out (ATO) programs result in de-escalation, but there
Autor:
Catherine DeVoe, Alexandra Hilts-Horeczko, Samantha Shenoy, Lusha Wang, Sarah B Doernberg, John H Dzundza, Larissa R. Graff, Rebecca L. Olin, Rosa Rodriguez-Monguio, Luke Strnad, Lloyd E. Damon, Trang D Trinh, Laura M Griffith
Publikováno v:
Open Forum Infectious Diseases
Background Febrile neutropenia (FN) is a common complication of cancer therapy and often necessitates prolonged antibiotic treatment. Antibiotic de-escalation can be challenging given tenuous clinical status. Furthermore, a microbiological or clinica