Zobrazeno 1 - 10
of 13
pro vyhledávání: ''
Autor:
Jing-Jing Jiang, Masaaki Murakami, Ikuma Nakagawa, Shuhei Shimoyama, Shintaro Hojyo, Osamu Ohara, Tatsuya Atsumi, Mona Uchida, Isao Matsumoto, John A. Chiorini, Mitsutoshi Ota, Yuki Tanaka, Rie Hasebe, Daisuke Kamimura, Yoshinori Hasegawa
Publikováno v:
Int Immunol
Sjögren’s syndrome (SS) is an autoimmune disease characterized by inflammation with lymphoid infiltration and destruction of the salivary glands. Although many genome-wide association studies have revealed disease-associated risk alleles, the func
Impact of RAS mutations on the immune infiltrate of colorectal liver metastases: A preliminary study
Autor:
Barbara Franceschini, Matteo Donadon, Flavio Milana, Luca Di Tommaso, Achille Anselmo, Federico Colombo, Sébastien Jaillon, Silvia Carnevale, Cristiana Soldani, Ana Lleo, Guido Torzilli, Matteo Cimino, Michela Anna Polidoro
Publikováno v:
Journal of Leukocyte Biology. 108:715-721
Kirsten rat sarcoma viral oncogene homolog KRAS proto-oncogene is the most common altered gene in colorectal cancer (CRC). Determining its mutational status, which is associated with worse prognosis and resistance to anti-epidermal growth factor rece
Autor:
Takayuki Kanazawa, Motohide Uemura, Yujiro Kidani, Makoto Yamasaki, Naganari Ohkura, Michinari Hirata, Taigo Kato, Kota Iwahori, Ryo Kato, Tetsuya Yoshida, Masaaki Sawada, Atsunari Kawashima, Yuichiro Doki, Shimon Sakaguchi, Akiko Morimoto-Okazawa, Takeshi Ujike, Kei Yamamoto, Kazutoshi Fujita, Koji Hatano, Yoko Yamamoto, Norio Nonomura, Hisashi Wada, Kentaro Nishida
Publikováno v:
International Immunology. 32:347-357
Objective CD4+CD8+ T cells are expressed in some cancer patients including those with renal cell carcinoma (RCC). However, no reports have mentioned the clinical importance of this expression. We evaluated the expression of CD4+CD8+ T cells in patien
Autor:
Tatsuhiro Shibata, Masafumi Ikeda, Naoto Gotohda, Kumiko Umemoto, Hiromi Nakamura, Takeshi Kuwata, Shinichiro Takahashi, Motohiro Kojima, Yosuke Togashi, Tokiyoshi Tanegashima, Tsubasa Nishikawa, Hiroyoshi Nishikawa, Yasuhito Arai, Mikiya Kato, Daisuke Sugiyama
Publikováno v:
International Immunology. 32:273-281
Biliary tract cancer (BTC) is an aggressive cancer with a poor prognosis partially due to the limited success in developing novel therapies, including molecularly targeted therapies and immunotherapies. Programmed cell death-1 (PD-1) blockade therapy
Autor:
Li Pan, Wei Liu, Xuedong Zhang, Zheng Zheng, Qingbo Guo, Bo Fu, Meng An, Xinqian Dong, Wenqiang Tang, Guotao Jia, Jinqiang Yan, Bin Zhang, Yingxue Li, Shuwei Liu, Anqi Zhang, Keyi Li
Publikováno v:
Clin Exp Immunol
Summary Tertiary lymphoid structure (TLS) provides a local and critical microenvironment for both cellular and humoral immunity and supports effective antigen presentation and lymphocyte activation. However, the gene expression profile and prognostic
Autor:
Caio Perez Gomes, Celso Arrais Rodrigues, João Bosco Pesquero, Ana Flavia Popi, Olivia Fonseca Souza, Bárbara Bomfim Muniz Moraes, Nilmar Silvio Moretti, Marcelo Pitombeira de Lacerda, Sergio Schenkman, Vivian Cristina de Oliveira, Juliana Terzi Maricato
Publikováno v:
Journal of Leukocyte Biology. 106:581-594
Chronic lymphocytic leukemia (CLL) is a chronic form of leukemia that originates from an abnormal expansion of CD5+B-1 cells. Deregulation in the BCR signaling is associated with B-cell transformation. Contrariwise to B-2 cells, BCR engagement in B-1
Autor:
Jesus Paula Carvalho, Paulo Francisco Ramos Margarido, Renata Ariza Marques Rossetti, Karla Alvarez, Enrique Boccardo, Edmund Chada Baracat, Simone Cardozo Stone, Noely Paula Cristina Lorenzi, Kaori Yokochi, Maricy Tacla, Ana Paula Lepique
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cervical cancer continues to be a public health problem in developing countries. Previous studies have shown that cervical cancer cells display markers of aerobic glycolysis, indicating that these tumors are likely to secrete lactate. Mostly, lactate
Publikováno v:
JNCI: Journal of the National Cancer Institute. 110:166-175
Despite increasing evidence supporting the clinical utility of immune infiltration in the estrogen receptor-negative (ER-) subtype, the prognostic value of immune infiltration for ER+ disease is not well defined.Quantitative immune scores of cell abu
Autor:
Yong-Bing Xiang, Xiao-Ou Shu, Ligia A. Pinto, Gloriana Shelton, Yu-Tang Gao, Troy J. Kemp, Anil K. Chaturvedi, Meredith S Shiels, Qiuyin Cai, Wei Hu, Bu Tian Ji, Wei Zheng, Qing Lan, Allan Hildesheim, Nathaniel Rothman
Publikováno v:
Carcinogenesis. 38:1004-1010
There is a paucity of data on risk factors for lung cancer among never smokers. Here, we have carried out the first large study of circulating inflammation markers and lung cancer risk among female never smokers in Shanghai. A study of 248 lung cance
Publikováno v:
Journal of Leukocyte Biology. 102:953-964
Leukocyte extravasation is a crucial feature of the normal immune response to disease and infection and is implicated in various pathologies during chronic inflammatory disease. P-Selectin glycoprotein ligand-1 (PSGL-1) is critical for leukocyte extr