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Publikováno v:
Journal of Antimicrobial Chemotherapy
The long-acting antiretroviral cabotegravir and rilpivirine combination has just received FDA, EMA and Health Canada approval. This novel drug delivery approach is about to revolutionize the therapy of people living with HIV, decreasing the 365 daily
Autor:
Hawazin A Shaikh, Mohammed E Mohammed Ali, Zied Gaifer, Basmah H AlJehani, Sheikheldin B Hussein
Publikováno v:
Transactions of The Royal Society of Tropical Medicine and Hygiene. 116:133-138
Background Brucellosis causes a disabling human disease and loss of animals' lives. The clinical significance of Brucella bacteremia is still unclear and Brucella identification in blood culture is suboptimal. Methods This was a retrospective study c
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:891-900
Background Pneumonia causes significant morbidity and mortality in children worldwide, especially in resource-poor settings. Accurate identification of bacterial etiology leads to timely antibiotic initiation, minimizing overuse, and development of r
Publikováno v:
J Antimicrob Chemother
In 2020, new vancomycin guidelines were released, recommending the transition from trough-based to AUC24 monitoring for adult and paediatric patients. Given the resources required to achieve this transition, there has been debate about the costs and
Autor:
Deepa Bhat, Shaily B Surti, Manoranjan Ranjit, Godi Sudhakar, P. Sridevi, Yogita Sharma, Bontha V. Babu, Jatin Sarmah
Publikováno v:
Transactions of The Royal Society of Tropical Medicine and Hygiene. 115:1434-1444
Background Sickle cell disease (SCD) is a serious public health problem, with >300 000 affected births worldwide each year. About 73% of the SCD-affected people in India belong to the tribal population. The Government of India is planning to implemen
Autor:
Kathryn Schlaffer, Yunyun Jiang, Kimberly C. Claeys, Surbhi Leekha, Stephanie Hitchcock, J. Kristie Johnson, Scott R. Evans, Richard J.H. Smith
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Three rapid diagnostic test panels (Verigene BC-GN, BioFire BCID, and BCID 2 [RUO]) were compared using the Desirability of Outcome Ranking Management of Antimicrobial Therapy (DOOR-MAT) to evaluate potential downstream antimicrobial prescribing deci
Autor:
Thomas P. Lodise, George L. Drusano
Publikováno v:
Clinical Infectious Diseases. 72:1497-1501
The revised vancomycin consensus guidelines recommended area under the curve (AUC)–guided dosing/monitoring for patients with serious invasive methicillin-resistant Staphylococcus aureus (MRSA) infections as a measure to minimize vancomycin-associa
Autor:
Kathryn Timberlake, Bruce R Dalton, Jackson J Stewart, Linda Dresser, Alfred S. Gin, Deonne Dersch-Mills, Sarah C J Jorgensen
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:2237-2251
The revised vancomycin guidelines recommend implementing AUC24-based therapeutic drug monitoring (TDM) using Bayesian methods in both adults and paediatrics. The motivation for this change was accumulating evidence showing aggressive dosing to achiev
Autor:
Lucy Lum Chai See, Devi Peramalah, Sharifah Faridah Syed Omar, Mohd Syis Zulkipli, Maznah Dahlui, Rafdzah Ahmad Zaki, Nor’Ashikin Jamil, Awang Bulgiba, Sanjay Rampal
Publikováno v:
Transactions of The Royal Society of Tropical Medicine and Hygiene. 115:764-771
Introduction: Dengue, an acute infectious disease caused by a flavivirus, is a threat to global health. There is sparse evidence exploring obesity and the development of a more severe dengue cases in adults. With increasing prevalence of obesity in a
Autor:
Amanda Gwee, Georgia Loane
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:682-685
This is a retrospective audit of teicoplanin dosing, drug-level monitoring, and outcomes in 29 children who received 31 courses of teicoplanin. Our study of noncritically ill children showed that the majority (35/43, 81%) of trough concentrations wer